The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli SM Brierley, PA Hughes, AJ Page, KY Kwan, CM Martin, TA O'Donnell, ... Gastroenterology 137 (6), 2084-2095. e3, 2009 | 313 | 2009 |
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3′, 5′-monophosphate J Castro, AM Harrington, PA Hughes, CM Martin, P Ge, CM Shea, H Jin, ... Gastroenterology 145 (6), 1334-1346. e11, 2013 | 312 | 2013 |
Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes PA Hughes, AM Harrington, J Castro, T Liebregts, B Adam, DJ Grasby, ... Gut 62 (10), 1456-1465, 2013 | 211 | 2013 |
A novel role for TRPM8 in visceral afferent function AM Harrington, PA Hughes, CM Martin, J Yang, J Castro, NJ Isaacs, ... Pain® 152 (7), 1459-1468, 2011 | 172 | 2011 |
TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity SM Brierley, J Castro, AM Harrington, PA Hughes, AJ Page, GY Rychkov, ... The Journal of physiology 589 (14), 3575-3593, 2011 | 158 | 2011 |
Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ... Nature communications 5 (1), 3165, 2014 | 138 | 2014 |
Diabetes‐related major lower limb amputation incidence is strongly related to diabetic foot service provision and improves with enhancement of services: peer review of the … RB Paisey, A Abbott, R Levenson, A Harrington, D Browne, J Moore, ... Diabetic Medicine 35 (1), 53-62, 2018 | 114 | 2018 |
Cholinergic neurotransmission and muscarinic receptors in the enteric nervous system AM Harrington, JM Hutson, BR Southwell Progress in histochemistry and cytochemistry 44 (4), 173-202, 2010 | 106 | 2010 |
Gastric vagal afferent modulation by leptin is influenced by food intake status SJ Kentish, TA O'Donnell, NJ Isaacs, RL Young, H Li, AM Harrington, ... The Journal of physiology 591 (7), 1921-1934, 2013 | 98 | 2013 |
α-Conotoxin Vc1. 1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors J Castro, AM Harrington, S Garcia-Caraballo, J Maddern, L Grundy, ... Gut 66 (6), 1083-1094, 2017 | 95 | 2017 |
Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1 MC Inserra, MR Israel, A Caldwell, J Castro, JR Deuis, AM Harrington, ... Scientific reports 7 (1), 42810, 2017 | 84 | 2017 |
Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity J Castro, AM Harrington, TM Lieu, S Garcia-Caraballo, J Maddern, ... JCI insight 4 (20), 2019 | 73 | 2019 |
Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction L Grundy, AM Harrington, J Castro, S Garcia-Caraballo, A Deiteren, ... JCI insight 3 (19), 2018 | 68 | 2018 |
Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1 L Grundy, A Caldwell, SG Caraballo, A Erickson, G Schober, J Castro, ... American Journal of Physiology-Renal Physiology, 2020 | 63 | 2020 |
Sprouting of colonic afferent central terminals and increased spinal mitogen‐activated protein kinase expression in a mouse model of chronic visceral hypersensitivity AM Harrington, SM Brierley, N Isaacs, PA Hughes, J Castro, ... Journal of Comparative Neurology 520 (10), 2241-2255, 2012 | 63 | 2012 |
Localization of muscarinic receptors M1R, M2R and M3R in the human colon AM Harrington, CJ Peck, L Liu, E Burcher, JM Hutson, BR Southwell Neurogastroenterology & Motility 22 (9), 999-e263, 2010 | 63 | 2010 |
Contribution of membrane receptor signalling to chronic visceral pain M Sadeghi, A Erickson, J Castro, A Deiteren, AM Harrington, L Grundy, ... The international journal of biochemistry & cell biology 98, 10-23, 2018 | 46 | 2018 |
Voltage‐gated sodium channels: (NaV)igating the field to determine their contribution to visceral nociception A Erickson, A Deiteren, AM Harrington, S Garcia‐Caraballo, J Castro, ... The Journal of physiology 596 (5), 785-807, 2018 | 44 | 2018 |
Fall in density, but not number of myenteric neurons and circular muscle nerve fibres in guinea‐pig colon with ageing CJ Peck, SD Samsuria, AM Harrington, SK King, JM Hutson, ... Neurogastroenterology & Motility 21 (10), 1075-e90, 2009 | 42 | 2009 |
Cyclic analogues of α‐conotoxin Vc1. 1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain J Castro, L Grundy, A Deiteren, AM Harrington, T O'Donnell, J Maddern, ... British journal of pharmacology 175 (12), 2384-2398, 2018 | 41 | 2018 |