Fate of haem iron in the malaria parasite Plasmodium falciparum. TJ Egan, JM Combrinck, J Egan, GR Hearne, HM Marques, S Ntenteni, ... Biochemical Journal 365 (Pt 2), 343, 2002 | 394 | 2002 |
Insights into the role of heme in the mechanism of action of antimalarials JM Combrinck, TE Mabotha, KK Ncokazi, MA Ambele, D Taylor, PJ Smith, ... ACS chemical biology 8 (1), 133-137, 2013 | 288 | 2013 |
Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts CC Musonda, D Taylor, J Lehman, J Gut, PJ Rosenthal, K Chibale Bioorganic & medicinal chemistry letters 14 (15), 3901-3905, 2004 | 101 | 2004 |
Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration R van der Westhuyzen, S Winks, CR Wilson, GA Boyle, RK Gessner, ... Journal of Medicinal Chemistry 58 (23), 9371-9381, 2015 | 94 | 2015 |
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box J Reader, ME van der Watt, D Taylor, C Le Manach, N Mittal, S Ottilie, ... Nature communications 12 (1), 269, 2021 | 75 | 2021 |
In vitro antimalarial activity, β-haematin inhibition and structure–activity relationships in a series of quinoline triazoles MC Joshi, KJ Wicht, D Taylor, R Hunter, PJ Smith, TJ Egan European journal of medicinal chemistry 69, 338-347, 2013 | 72 | 2013 |
UCT943, a next-generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria C Brunschwig, N Lawrence, D Taylor, E Abay, M Njoroge, GS Basarab, ... Antimicrobial agents and chemotherapy 62 (9), 10.1128/aac. 00012-18, 2018 | 67 | 2018 |
Synthesis and evaluation of new polynuclear organometallic Ru (II), Rh (III) and Ir (III) pyridyl ester complexes as in vitro antiparasitic and antitumor agents P Chellan, KM Land, A Shokar, A Au, SH An, D Taylor, PJ Smith, T Riedel, ... Dalton Transactions 43 (2), 513-526, 2014 | 61 | 2014 |
Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy MN Aminake, A Mahajan, V Kumar, R Hans, L Wiesner, D Taylor, ... Bioorganic & medicinal chemistry 20 (17), 5277-5289, 2012 | 58 | 2012 |
Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1 C Le Manach, D Gonzàlez Cabrera, F Douelle, AT Nchinda, Y Younis, ... Journal of medicinal chemistry 57 (6), 2789-2798, 2014 | 55 | 2014 |
Identification of a potential antimalarial drug candidate from a series of 2-aminopyrazines by optimization of aqueous solubility and potency across the parasite life cycle C Le Manach, AT Nchinda, T Paquet, D Gonzàlez Cabrera, Y Younis, ... Journal of medicinal chemistry 59 (21), 9890-9905, 2016 | 51 | 2016 |
Mathematics and science teacher education in South Africa: A review of research, policy and practice in times of change J Adler, C Pournara, D Taylor, B Thorne, G Moletsane African Journal of Research in Mathematics, Science and Technology Education …, 2009 | 51 | 2009 |
Structure-activity relationship studies of antiplasmodial cyclometallated ruthenium (II), rhodium (III) and iridium (III) complexes of 2-phenylbenzimidazoles L Rylands, A Welsh, K Maepa, T Stringer, D Taylor, K Chibale, GS Smith European Journal of Medicinal Chemistry 161, 11-21, 2019 | 50 | 2019 |
Secondary physical science teachers' conceptions of science teaching in a context of change DL Taylor, S Booth International Journal of Science Education 37 (8), 1299-1320, 2015 | 43 | 2015 |
Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a softfocus kinase library: Part 2 C Le Manach, T Paquet, D Gonzàlez Cabrera, Y Younis, D Taylor, ... Journal of medicinal chemistry 57 (21), 8839-8848, 2014 | 43 | 2014 |
Di-and trinuclear ruthenium-, rhodium-, and iridium-functionalized pyridyl aromatic ethers: a new class of antiparasitic agents P Chellan, KM Land, A Shokar, A Au, SH An, D Taylor, PJ Smith, ... Organometallics 32 (17), 4793-4804, 2013 | 42 | 2013 |
Synthesis, characterization and antimalarial activity of new chromium arene–quinoline half sandwich complexes L Glans, D Taylor, C de Kock, PJ Smith, M Haukka, JR Moss, ... Journal of inorganic biochemistry 105 (7), 985-990, 2011 | 42 | 2011 |
Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors … N Kandepedu, D Gonzàlez Cabrera, S Eedubilli, D Taylor, C Brunschwig, ... Journal of medicinal chemistry 61 (13), 5692-5703, 2018 | 41 | 2018 |
Valuing IKS in successive South African physical sciences curricula DL Taylor, A Cameron African Journal of Research in Mathematics, Science and Technology Education …, 2016 | 41 | 2016 |
Heterometallic half-sandwich complexes containing a ferrocenyl motif: Synthesis, molecular structure, electrochemistry and antiplasmodial evaluation W Nkoana, D Nyoni, P Chellan, T Stringer, D Taylor, PJ Smith, AT Hutton, ... Journal of Organometallic Chemistry 752, 67-75, 2014 | 39 | 2014 |