Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin MOW Grimm, HS Grimm, AJ Pätzold, EG Zinser, R Halonen, M Duering, ... Nature cell biology 7 (11), 1118-1123, 2005 | 554 | 2005 |
Altered gut microbiome composition and tryptic activity of the 5xFAD Alzheimer’s mouse model C Brandscheid, F Schuck, S Reinhardt, KH Schäfer, CU Pietrzik, M Grimm, ... Journal of Alzheimer's Disease 56 (2), 775-788, 2017 | 269 | 2017 |
Docosahexaenoic acid reduces amyloid β production via multiple pleiotropic mechanisms MOW Grimm, J Kuchenbecker, S Grösgen, VK Burg, B Hundsdörfer, ... Journal of Biological Chemistry 286 (16), 14028-14039, 2011 | 257 | 2011 |
Alzheimer’s disease: the lipid connection T Hartmann, J Kuchenbecker, MOW Grimm Journal of neurochemistry 103, 159-170, 2007 | 254 | 2007 |
24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial H Soininen, A Solomon, PJ Visser, SB Hendrix, K Blennow, M Kivipelto, ... The Lancet Neurology 16 (12), 965-975, 2017 | 223 | 2017 |
Neprilysin and Aβ clearance: impact of the APP intracellular domain in NEP regulation and implications in Alzheimer’s disease MOW Grimm, J Mett, CP Stahlmann, VJ Haupenthal, VC Zimmer, ... Frontiers in aging neuroscience 5, 98, 2013 | 198 | 2013 |
Independent inhibition of Alzheimer disease β-and γ-secretase cleavage by lowered cholesterol levels MOW Grimm, HS Grimm, I Tomic, K Beyreuther, T Hartmann, C Bergmann Journal of Biological Chemistry 283 (17), 11302-11311, 2008 | 162 | 2008 |
Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study VK Burg, HS Grimm, TL Rothhaar, S Grösgen, B Hundsdörfer, ... Journal of Neuroscience 33 (41), 16072-16087, 2013 | 152 | 2013 |
From brain to food: Analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin–plasmalogens derivates in Alzheimer's disease human post mortem brains and … MOW Grimm, S Grösgen, M Riemenschneider, H Tanila, HS Grimm, ... Journal of Chromatography A 1218 (42), 7713-7722, 2011 | 141 | 2011 |
Mean age of onset in familial Alzheimer's disease is determined by amyloid beta 42 M Duering, MOW Grimm, HS Grimm, J Schröder, T Hartmann Neurobiology of aging 26 (6), 785-788, 2005 | 136 | 2005 |
Plasmalogen synthesis is regulated via alkyl‐dihydroxyacetonephosphate‐synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease MOW Grimm, J Kuchenbecker, TL Rothhaar, S Grösgen, B Hundsdörfer, ... Journal of neurochemistry 116 (5), 916-925, 2011 | 130 | 2011 |
The impact of vitamin E and other fat-soluble vitamins on Alzheimer s disease MOW Grimm, J Mett, T Hartmann International journal of molecular sciences 17 (11), 1785, 2016 | 126 | 2016 |
36‐month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease H Soininen, A Solomon, PJ Visser, SB Hendrix, K Blennow, M Kivipelto, ... Alzheimer's & dementia 17 (1), 29-40, 2021 | 121 | 2021 |
Dietary intake of plant sterols stably increases plant sterol levels in the murine brain T Vanmierlo, O Weingärtner, S van der Pol, C Husche, A Kerksiek, ... Journal of lipid research 53 (4), 726-735, 2012 | 120 | 2012 |
Unfolded protein response signaling by transcription factor XBP‐1 regulates ADAM10 and is affected in Alzheimer's disease S Reinhardt, F Schuck, S Grösgen, M Riemenschneider, T Hartmann, ... The FASEB Journal 28 (2), 978-997, 2014 | 114 | 2014 |
Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention: Thematic Review Series: ApoE and Lipid Homeostasis … MOW Grimm, DM Michaelson, T Hartmann Journal of lipid research 58 (11), 2083-2101, 2017 | 110 | 2017 |
Role of amyloid beta in lipid homeostasis S Grösgen, MOW Grimm, P Frieß, T Hartmann Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 110 | 2010 |
APP function and lipids: a bidirectional link MOW Grimm, J Mett, HS Grimm, T Hartmann Frontiers in molecular neuroscience 10, 63, 2017 | 103 | 2017 |
The impact of cholesterol, DHA, and sphingolipids on Alzheimer’s disease MOW Grimm, VC Zimmer, J Lehmann, HS Grimm, T Hartmann BioMed research international 2013 (1), 814390, 2013 | 102 | 2013 |
Alzheimer's disease pathology is attenuated in a CD 38‐deficient mouse model E Blacher, T Dadali, A Bespalko, VJ Haupenthal, MOW Grimm, ... Annals of neurology 78 (1), 88-103, 2015 | 100 | 2015 |