R loops and their composite cancer connections JP Wells, J White, PC Stirling Trends in cancer 5 (10), 619-631, 2019 | 75 | 2019 |
MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts EYC Chang, S Tsai, MJ Aristizabal, JP Wells, Y Coulombe, FF Busatto, ... Nature communications 10 (1), 4265, 2019 | 73 | 2019 |
ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork S Kim, N Kang, SH Park, J Wells, T Hwang, E Ryu, B Kim, S Hwang, ... Nucleic acids research 48 (13), 7218-7238, 2020 | 66 | 2020 |
ARID1A regulates R-loop associated DNA replication stress S Tsai, LA Fournier, EY Chang, JP Wells, SW Minaker, YD Zhu, ... PLoS Genetics 17 (4), e1009238, 2021 | 65 | 2021 |
Structure and function of a lignostilbene-α,β-dioxygenase orthologue from Pseudomonas brassicacearum PC Loewen, J Switala, JP Wells, F Huang, AT Zara, JS Allingham, ... BMC biochemistry 19, 1-13, 2018 | 17 | 2018 |
RAD18 opposes transcription-associated genome instability through FANCD2 recruitment JP Wells, EYC Chang, L Dinatto, J White, S Ryall, PC Stirling PLoS Genetics 18 (12), e1010309, 2022 | 7 | 2022 |
R loops and their composite cancer connections. Trends Cancer 5, 619–631 JP Wells, J White, PC Stirling | 5 | 2019 |
MRE11-RAD50-NBS1 activates Fanconi Anemia R-loop suppression at transcription-replication conflicts EY Chang, JP Wells, SH Tsai, Y Coulombe, YA Chan, YD Zhu, ... bioRxiv, 472654, 2018 | 1 | 2018 |
Genome-Wide CRISPR Screen Identifies KEAP1 Perturbation as a Vulnerability of ARID1A-Deficient Cells LA Fournier, F Kalantari, JP Wells, JS Lee, G Trigo-Gonzalez, MM Moksa, ... Cancers 16 (17), 2949, 2024 | | 2024 |
Genome-wide CRISPR screen identifies KEAP1 as a genetic dependency of ARID1A in an ovarian clear cell carcinoma model LA Fournier, F Kalantari, JP Wells, JS Lee, G Trigo-Gonzalez, MM Moksa, ... bioRxiv, 2023.11. 14.566591, 2023 | | 2023 |
Proliferating cell nuclear antigen ubiquitination as a central regulator of transcriptional stress JP Wells University of British Columbia, 2023 | | 2023 |