关注
Aaron John Balana
Aaron John Balana
Scientist, Genentech
在 gene.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson’s disease
PM Levine, A Galesic, AT Balana, AL Mahul-Mellier, MX Navarro, ...
Proceedings of the National Academy of Sciences 116 (5), 1511-1519, 2019
1932019
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
AT Balana, PM Levine, TW Craven, S Mukherjee, NJ Pedowitz, SP Moon, ...
Nature chemistry 13 (5), 441-450, 2021
662021
O-GlcNAc engineering of GPCR peptide-agonists improves their stability and in vivo activity
PM Levine, AT Balana, E Sturchler, C Koole, H Noda, B Zarzycka, ...
Journal of the American Chemical Society 141 (36), 14210-14219, 2019
392019
O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein
PM Levine, CA De Leon, A Galesic, A Balana, NP Marotta, YE Lewis, ...
Bioorganic & medicinal chemistry 25 (18), 4977-4982, 2017
352017
Mechanistic roles for altered O-GlcNAcylation in neurodegenerative disorders
AT Balana, MR Pratt
Biochemical Journal 478 (14), 2733-2758, 2021
332021
Ubiquitination can change the structure of the α-synuclein amyloid fiber in a site selective fashion
SP Moon, AT Balana, A Galesic, A Rakshit, MR Pratt
The Journal of organic chemistry 85 (3), 1548-1555, 2019
252019
Comparison of N-Acetyl-Glucosamine to Other Monosaccharides Reveals Structural Differences for the Inhibition of α-Synuclein Aggregation
A Galesic, A Rakshit, G Cutolo, RP Pacheco, AT Balana, SP Moon, ...
ACS chemical biology 16 (1), 14-19, 2021
242021
O-GlcNAcylation of high mobility group box 1 (HMGB1) alters its DNA binding and DNA damage processing activities
AT Balana, A Mukherjee, H Nagpal, SP Moon, B Fierz, KM Vasquez, ...
Journal of the American Chemical Society 143 (39), 16030-16040, 2021
202021
Consequences of post-translational modifications on amyloid proteins as revealed by protein semisynthesis
SP Moon, AT Balana, MR Pratt
Current opinion in chemical biology 64, 76-89, 2021
142021
O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology
AT Balana, AL Mahul-Mellier, BA Nguyen, M Horvath, A Javed, ER Hard, ...
Biorxiv, 2023
112023
Multifaceted regulation of Akt by diverse C-terminal post-translational modifications
AL Salguero, M Chen, AT Balana, N Chu, H Jiang, BA Palanski, H Bae, ...
ACS chemical biology 17 (1), 68-76, 2021
102021
O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology
AT Balana, AL Mahul-Mellier, BA Nguyen, M Horvath, A Javed, ER Hard, ...
Nature chemical biology, 1-10, 2024
82024
O-GlcNAcylated peptides and proteins for structural and functional studies
AT Balana, SP Moon, MR Pratt
Current opinion in structural biology 68, 84-93, 2021
62021
Generation of Potent and Stable GLP-1 Analogues Via “Serine Ligation”
PM Levine, TW Craven, X Li, AT Balana, GH Bird, M Godes, PJ Salveson, ...
ACS chemical biology 17 (4), 804-809, 2022
32022
Top/Middle-Down Characterization of α-Synuclein Glycoforms
SA Miller, K Jeanne Dit Fouque, ER Hard, AT Balana, D Kaplan, ...
Analytical chemistry 95 (49), 18039-18045, 2023
12023
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants
S Liu, EJ Daley, LML Tran, Z Yu, M Reyes, T Dean, A Khatri, PM Levine, ...
Journal of the American Chemical Society 146 (10), 6522-6529, 2024
2024
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