α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson’s disease PM Levine, A Galesic, AT Balana, AL Mahul-Mellier, MX Navarro, ... Proceedings of the National Academy of Sciences 116 (5), 1511-1519, 2019 | 193 | 2019 |
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity AT Balana, PM Levine, TW Craven, S Mukherjee, NJ Pedowitz, SP Moon, ... Nature chemistry 13 (5), 441-450, 2021 | 66 | 2021 |
O-GlcNAc engineering of GPCR peptide-agonists improves their stability and in vivo activity PM Levine, AT Balana, E Sturchler, C Koole, H Noda, B Zarzycka, ... Journal of the American Chemical Society 141 (36), 14210-14219, 2019 | 39 | 2019 |
O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein PM Levine, CA De Leon, A Galesic, A Balana, NP Marotta, YE Lewis, ... Bioorganic & medicinal chemistry 25 (18), 4977-4982, 2017 | 35 | 2017 |
Mechanistic roles for altered O-GlcNAcylation in neurodegenerative disorders AT Balana, MR Pratt Biochemical Journal 478 (14), 2733-2758, 2021 | 33 | 2021 |
Ubiquitination can change the structure of the α-synuclein amyloid fiber in a site selective fashion SP Moon, AT Balana, A Galesic, A Rakshit, MR Pratt The Journal of organic chemistry 85 (3), 1548-1555, 2019 | 25 | 2019 |
Comparison of N-Acetyl-Glucosamine to Other Monosaccharides Reveals Structural Differences for the Inhibition of α-Synuclein Aggregation A Galesic, A Rakshit, G Cutolo, RP Pacheco, AT Balana, SP Moon, ... ACS chemical biology 16 (1), 14-19, 2021 | 24 | 2021 |
O-GlcNAcylation of high mobility group box 1 (HMGB1) alters its DNA binding and DNA damage processing activities AT Balana, A Mukherjee, H Nagpal, SP Moon, B Fierz, KM Vasquez, ... Journal of the American Chemical Society 143 (39), 16030-16040, 2021 | 20 | 2021 |
Consequences of post-translational modifications on amyloid proteins as revealed by protein semisynthesis SP Moon, AT Balana, MR Pratt Current opinion in chemical biology 64, 76-89, 2021 | 14 | 2021 |
O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology AT Balana, AL Mahul-Mellier, BA Nguyen, M Horvath, A Javed, ER Hard, ... Biorxiv, 2023 | 11 | 2023 |
Multifaceted regulation of Akt by diverse C-terminal post-translational modifications AL Salguero, M Chen, AT Balana, N Chu, H Jiang, BA Palanski, H Bae, ... ACS chemical biology 17 (1), 68-76, 2021 | 10 | 2021 |
O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology AT Balana, AL Mahul-Mellier, BA Nguyen, M Horvath, A Javed, ER Hard, ... Nature chemical biology, 1-10, 2024 | 8 | 2024 |
O-GlcNAcylated peptides and proteins for structural and functional studies AT Balana, SP Moon, MR Pratt Current opinion in structural biology 68, 84-93, 2021 | 6 | 2021 |
Generation of Potent and Stable GLP-1 Analogues Via “Serine Ligation” PM Levine, TW Craven, X Li, AT Balana, GH Bird, M Godes, PJ Salveson, ... ACS chemical biology 17 (4), 804-809, 2022 | 3 | 2022 |
Top/Middle-Down Characterization of α-Synuclein Glycoforms SA Miller, K Jeanne Dit Fouque, ER Hard, AT Balana, D Kaplan, ... Analytical chemistry 95 (49), 18039-18045, 2023 | 1 | 2023 |
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants S Liu, EJ Daley, LML Tran, Z Yu, M Reyes, T Dean, A Khatri, PM Levine, ... Journal of the American Chemical Society 146 (10), 6522-6529, 2024 | | 2024 |