Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease RTY Teo, X Hong, L Yu-Taeger, Y Huang, LJ Tan, Y Xie, XV To, L Guo, ... Human molecular genetics 25 (13), 2621-2632, 2016 | 107 | 2016 |
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease M Garcia-Miralles, X Hong, LJ Tan, NS Caron, Y Huang, XV To, RY Lin, ... Scientific reports 6 (1), 31652, 2016 | 77 | 2016 |
ABCA8 regulates cholesterol efflux and high-density lipoprotein cholesterol levels L Trigueros-Motos, JC van Capelleveen, F Torta, D Castano, LH Zhang, ... Arteriosclerosis, thrombosis, and vascular biology 37 (11), 2147-2155, 2017 | 69 | 2017 |
Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease M Garcia-Miralles, J Ooi, CF Bardile, LJ Tan, M George, CL Drum, RY Lin, ... Experimental neurology 278, 4-10, 2016 | 52 | 2016 |
Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice M Garcia-Miralles, M Geva, JY Tan, NABM Yusof, Y Cha, R Kusko, LJ Tan, ... JCI insight 2 (23), 2017 | 42 | 2017 |
Laquinimod treatment improves myelination deficits at the transcriptional and ultrastructural levels in the YAC128 mouse model of Huntington disease M Garcia-Miralles, NABM Yusof, JY Tan, CI Radulescu, H Sidik, LJ Tan, ... Molecular neurobiology 56, 4464-4478, 2019 | 41 | 2019 |
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse R Kusko, J Dreymann, J Ross, Y Cha, R Escalante-Chong, ... Molecular Neurodegeneration 13, 1-15, 2018 | 39 | 2018 |
Impaired remyelination in a mouse model of Huntington disease RTY Teo, C Ferrari Bardile, YL Tay, NABM Yusof, CA Kreidy, LJ Tan, ... Molecular neurobiology 56, 6873-6882, 2019 | 22 | 2019 |
Connectomic imaging reveals Huntington‐related pathological and pharmaceutical effects in a mouse model WT Chang, F Puspitasari, M Garcia‐Miralles, LY Yeow, HC Tay, KB Koh, ... NMR in Biomedicine 31 (12), e4007, 2018 | 16 | 2018 |
Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult A Ziaei, M Garcia‐Miralles, CI Radulescu, H Sidik, A Silvin, HG Bae, ... Brain Pathology 32 (5), e13064, 2022 | 10 | 2022 |
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease. Sci Rep 6: 31652 M Garcia-Miralles, X Hong, LJ Tan, NS Caron, Y Huang, XV To, RY Lin, ... | 7 | 2016 |
L6 Evaluation of pridopidine in the transgenic yac128 mouse model of huntington’s disease MG Miralles, LJ Tan, M Lim, M Geva, MR Hayden, MA Pouladi Journal of Neurology, Neurosurgery & Psychiatry 87 (Suppl 1), A92-A92, 2016 | 4 | 2016 |
Ermin deficiency as an inside-out model of inflammatory dysmyelination A Ziaei, M Garcia-Miralles, CI Radulescu, H Sidik, A Silvin, HG Bae, ... BioRxiv, 2020.06. 16.154781, 2020 | 1 | 2020 |
Understanding early molecular mechanisms of abnormal myelination in neurological conditions by characterising Ermin deficiency SL Oh, A Ziaei, LJ Tan, KH Utami, MA Pouladi, SR Langley | | 2024 |
Evaluation of pridopidine in the transgenic YAC128 mouse model of Huntington disease M Garcia-Miralles, N Yosuf, JY Tan, R Kusko, LJ Tan, X Xu, A Orbach, ... JOURNAL OF NEUROCHEMISTRY 142, 219-219, 2017 | | 2017 |
L8 Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of huntington’s disease MG Miralles, X Hong, NS Caron, LJ Tan, Y Huang, XV To, RY Lin, ... Journal of Neurology, Neurosurgery & Psychiatry 87 (Suppl 1), A92-A93, 2016 | | 2016 |
TBM and DTI reveal structural changes by memantine treatment in YAC128 mouse model of Huntington disease X Hong, M Garcia-Miralles, LY Yeow, XV To, BCM Yeo, F Puspitasari, ... Proc. Intl. Soc. Mag. Reson. Med 24, 4440, 2016 | | 2016 |
Imaging effects of memantine treatment in a mouse model of Huntington disease using evoked and resting-state fMRI WT Chang, F Puspitasari, LY Yeow, HC Tay, MG Miralles, KB Koh, LJ Tan, ... | | |