Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands. EL Barker, RS Westphal, D Schmidt, E Sanders-Bush Journal of Biological Chemistry 269 (16), 11687-11690, 1994 | 340 | 1994 |
Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor JE Burdette, J Liu, S Chen, DS Fabricant, CE Piersen, EL Barker, ... Journal of Agricultural and Food Chemistry 51 (19), 5661-5670, 2003 | 301 | 2003 |
Norepinephrine and serotonin transporters: molecular targets of antidepressant drugs EL Barker, RD Blakely Psychopharmacology: the fourth generation of progress 28, 321-333, 1995 | 288 | 1995 |
Serotonin 5-hydroxytryptamine2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves DM Kurrasch-Orbaugh, VJ Watts, EL Barker, DE Nichols Journal of Pharmacology and Experimental Therapeutics 304 (1), 229-237, 2003 | 207 | 2003 |
Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter EL Barker, KR Moore, F Rakhshan, RD Blakely Journal of Neuroscience 19 (12), 4705-4717, 1999 | 207 | 1999 |
Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster. LL Demchyshyn, ZB Pristupa, KS Sugamori, EL Barker, RD Blakely, ... Proceedings of the National Academy of Sciences 91 (11), 5158-5162, 1994 | 195 | 1994 |
High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis: an aromatic residue in transmembrane domain I dictates species-selective … EL Barker, MA Perlman, EM Adkins, WJ Houlihan, ZB Pristupa, HB Niznik, ... Journal of Biological Chemistry 273 (31), 19459-19468, 1998 | 187 | 1998 |
Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide TA Day, F Rakhshan, DG Deutsch, EL Barker Molecular Pharmacology 59 (6), 1369-1375, 2001 | 176 | 2001 |
D2 dopamine receptors modulate Gα-subunit coupling of the CB1 cannabinoid receptor A Jarrahian, VJ Watts, EL Barker Journal of Pharmacology and Experimental Therapeutics 308 (3), 880-886, 2004 | 174 | 2004 |
Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines JB Blair, D Kurrasch-Orbaugh, D Marona-Lewicka, MG Cumbay, VJ Watts, ... Journal of medicinal chemistry 43 (24), 4701-4710, 2000 | 174 | 2000 |
Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells F Rakhshan, TA Day, RD Blakely, EL Barker Journal of Pharmacology and Experimental Therapeutics 292 (3), 960-967, 2000 | 174 | 2000 |
A role for caveolae/lipid rafts in the uptake and recycling of the endogenous cannabinoid anandamide MJ McFarland, AC Porter, FR Rakhshan, DS Rawat, RA Gibbs, EL Barker Journal of Biological Chemistry 279 (40), 41991-41997, 2004 | 170 | 2004 |
Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing. H Canton, RB Emeson, EL Barker, JR Backstrom, JT Lu, MS Chang, ... Molecular pharmacology 50 (4), 799-807, 1996 | 166 | 1996 |
Assessing Cholesterol Storage in Live Cells and C. elegans by Stimulated Raman Scattering Imaging of Phenyl-Diyne Cholesterol HJ Lee, W Zhang, D Zhang, Y Yang, B Liu, EL Barker, KK Buhman, ... Scientific reports 5 (1), 7930, 2015 | 149 | 2015 |
Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands. EL Barker, HL Kimmel, RD Blakely Molecular pharmacology 46 (5), 799-807, 1994 | 149 | 1994 |
Anandamide transport MJ McFarland, EL Barker Pharmacology & therapeutics 104 (2), 117-135, 2004 | 142 | 2004 |
Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter. EL Barker, RD Blakely Molecular Pharmacology 50 (4), 957-965, 1996 | 115 | 1996 |
Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition EM Adkins, EL Barker, RD Blakely Molecular pharmacology 59 (3), 514-523, 2001 | 105 | 2001 |
Serotonin transporters: implications for antidepressant drug development KJ White, CC Walline, EL Barker Drug Addiction: From Basic Research to Therapy, 193-215, 2008 | 100 | 2008 |
5-hydroxytryptamine1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2, 5-dimethoxyphenyl)-2-aminopropane. EL Barker, E Sanders-Bush Molecular pharmacology 44 (4), 725-730, 1993 | 75 | 1993 |