Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel … N Lolak, S Akocak, C Türkeş, P Taslimi, M Işık, Ş Beydemir, İ Gülçin, ... Bioorganic chemistry 100, 103897, 2020 | 142 | 2020 |
One-pot three-component synthesis of 2-Amino-4H-Chromene derivatives by using monodisperse Pd nanomaterials anchored graphene oxide as highly efficient and recyclable catalyst S Akocak, B Şen, N Lolak, A Şavk, M Koca, S Kuzu, F Şen Nano-Structures & Nano-Objects 11, 25-31, 2017 | 96 | 2017 |
Synthesis, characterization, and inhibition study of novel substituted phenylureido sulfaguanidine derivatives as α‐glycosidase and cholinesterase inhibitors S Akocak, P Taslimi, N Lolak, M Işık, M Durgun, Y Budak, C Türkeş, ... Chemistry & biodiversity 18 (4), e2000958, 2021 | 72 | 2021 |
Synthesis, characterization, biological evaluation, and in silico studies of novel 1, 3‐diaryltriazene‐substituted sulfathiazole derivatives M Işık, S Akocak, N Lolak, P Taslimi, C Türkeş, İ Gülçin, M Durgun, ... Archiv Der Pharmazie 353 (9), 2000102, 2020 | 69 | 2020 |
Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors C Türkeş, S Akocak, M Işık, N Lolak, P Taslimi, M Durgun, İ Gülçin, ... Journal of Biomolecular Structure and Dynamics 40 (19), 8752-8764, 2022 | 67 | 2022 |
Design and synthesis of novel 1, 3-diaryltriazene-substituted sulfonamides as potent and selective carbonic anhydrase II inhibitors N Lolak, S Akocak, S Bua, M Koca, CT Supuran Bioorganic chemistry 77, 542-547, 2018 | 63 | 2018 |
Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators S Akocak, N Lolak, D Vullo, M Durgun, CT Supuran Journal of enzyme inhibition and medicinal chemistry 32 (1), 1305-1312, 2017 | 63 | 2017 |
Composites of palladium–nickel alloy nanoparticles and graphene oxide for the Knoevenagel condensation of aldehydes with malononitrile N Lolak, E Kuyuldar, H Burhan, H Goksu, S Akocak, F Sen ACS omega 4 (4), 6848-6853, 2019 | 61 | 2019 |
Synthesis and biological evaluation of novel aromatic and heterocyclic bis-sulfonamide Schiff bases as carbonic anhydrase I, II, VII and IX inhibitors S Akocak, N Lolak, A Nocentini, G Karakoc, A Tufan, CT Supuran Bioorganic & medicinal chemistry 25 (12), 3093-3097, 2017 | 61 | 2017 |
Discovery of new ureido benzenesulfonamides incorporating 1, 3, 5-triazine moieties as carbonic anhydrase I, II, IX and XII inhibitors N Lolak, S Akocak, S Bua, RKK Sanku, CT Supuran Bioorganic & medicinal chemistry 27 (8), 1588-1594, 2019 | 58 | 2019 |
Discovery of novel 1, 3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors S Akocak, N Lolak, S Bua, CT Supuran Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 1575-1580, 2018 | 56 | 2018 |
Design, synthesis and biological evaluation of novel ureido benzenesulfonamides incorporating 1, 3, 5-triazine moieties as potent carbonic anhydrase IX inhibitors N Lolak, S Akocak, S Bua, CT Supuran Bioorganic Chemistry 82, 117-122, 2019 | 55 | 2019 |
Bimetallic PdRu/graphene oxide based Catalysts for one-pot three-component synthesis of 2-amino-4H-chromene derivatives B Şen, N Lolak, Ö Paralı, M Koca, A Şavk, S Akocak, F Şen Nano-structures & Nano-objects 12, 33-40, 2017 | 51 | 2017 |
Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase G Yapar, HE Duran, N Lolak, S Akocak, C Türkeş, M Durgun, M Işık, ... Bioorganic chemistry 117, 105473, 2021 | 47 | 2021 |
Sulphonamides incorporating 1, 3, 5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile N Lolak, M Boga, M Tuneg, G Karakoc, S Akocak, CT Supuran Journal of enzyme inhibition and medicinal chemistry 35 (1), 424-431, 2020 | 40 | 2020 |
Synthesis and biological evaluation of novel N, N′-diaryl cyanoguanidines acting as potent and selective carbonic anhydrase II inhibitors S Akocak, N Lolak, S Bua, I Turel, CT Supuran Bioorganic Chemistry 77, 245-251, 2018 | 39 | 2018 |
Biological effects of a new set 1,2,4-triazolo[1,5-a]quinazolines on heart rate and blood pressure R Al-Salahi, KE El-Tahir, I Alswaidan, N Lolak, M Hamidaddin, M Marzouk Chemistry Central Journal 8, 1-8, 2014 | 37 | 2014 |
Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors N Lolak, S Akocak, M Durgun, HE Duran, A Necip, C Türkeş, M Işık, ... Molecular Diversity 27 (4), 1735-1749, 2023 | 33 | 2023 |
Synthesis and cytotoxic activities of novel copper and silver complexes of 1, 3-diaryltriazene-substituted sulfonamides D Canakci, I Koyuncu, N Lolak, M Durgun, S Akocak, CT Supuran Journal of enzyme inhibition and medicinal chemistry 34 (1), 110-116, 2019 | 33 | 2019 |
α-Carbonic anhydrases are strongly activated by spinaceamine derivatives S Akocak, N Lolak, S Bua, A Nocentini, G Karakoc, CT Supuran Bioorganic & Medicinal Chemistry 27 (5), 800-804, 2019 | 27 | 2019 |