Unity in the biochemistry of the iron-storage proteins ferritin and bacterioferritin K Honarmand Ebrahimi, PL Hagedoorn, WR Hagen Chemical reviews 115 (1), 295-326, 2015 | 289 | 2015 |
The catalytic center of ferritin regulates iron storage via Fe(II)-Fe(III) displacement K Honarmand Ebrahimi, E Bill, PL Hagedoorn, WR Hagen Nature chemical biology 8 (11), 941-948, 2012 | 139 | 2012 |
A conserved tyrosine in ferritin is a molecular capacitor KH Ebrahimi, PL Hagedoorn, WR Hagen ChemBioChem 14 (9), 1123-1133, 2013 | 50 | 2013 |
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics TM Quinn, EE Gaughan, A Bruce, J Antonelli, R O'Connor, F Li, ... EBioMedicine 76, 2022 | 44 | 2022 |
Mechanistic insights into the three steps of poly (ADP-ribosylation) reversal JGM Rack, Q Liu, V Zorzini, J Voorneveld, A Ariza, ... Nature Communications 12 (1), 4581, 2021 | 44 | 2021 |
Catalysis of iron core formation in Pyrococcus furiosus ferritin K Honarmand Ebrahimi, PL Hagedoorn, JA Jongejan, WR Hagen JBIC Journal of Biological Inorganic Chemistry 14, 1265-1274, 2009 | 44 | 2009 |
A unifying view of the broad-spectrum antiviral activity of RSAD2 (viperin) based on its radical-SAM chemistry K Honarmand Ebrahimi Metallomics 10 (4), 539-552, 2018 | 42 | 2018 |
Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium A Vaughan-Jackson, S Stodolak, KH Ebrahimi, C Browne, PK Reardon, ... Stem Cell Reports 16 (7), 1735-1748, 2021 | 38 | 2021 |
The workings of ferritin: a crossroad of opinions WR Hagen, PL Hagedoorn, K Honarmand Ebrahimi Metallomics 9 (6), 595-605, 2017 | 38 | 2017 |
Viperin, through its radical‐SAM activity, depletes cellular nucleotide pools and interferes with mitochondrial metabolism to inhibit viral replication KH Ebrahimi, D Howie, JS Rowbotham, J McCullagh, FA Armstrong, ... FEBS letters 594 (10), 1624-1630, 2020 | 35 | 2020 |
Iron–sulfur clusters as inhibitors and catalysts of viral replication K Honarmand Ebrahimi, S Ciofi-Baffoni, PL Hagedoorn, Y Nicolet, ... Nature Chemistry 14 (3), 253-266, 2022 | 33 | 2022 |
The radical‐SAM enzyme Viperin catalyzes reductive addition of a 5′‐deoxyadenosyl radical to UDP‐glucose in vitro K Honarmand Ebrahimi, SB Carr, J McCullagh, J Wickens, NH Rees, ... FEBS Letters, 2017 | 33 | 2017 |
A synthetic peptide with the putative iron binding motif of amyloid precursor protein (APP) does not catalytically oxidize iron KH Ebrahimi, PL Hagedoorn, WR Hagen Public Library of Science 7 (8), e40287, 2012 | 33 | 2012 |
SARS‐CoV‐2 spike glycoprotein‐binding proteins expressed by upper respiratory tract bacteria may prevent severe viral infection K Honarmand Ebrahimi FEBS Letters, 2020 | 31 | 2020 |
ddhCTP produced by the radical‐SAM activity of RSAD2 (viperin) inhibits the NAD+‐dependent activity of enzymes to modulate metabolism K Honarmand Ebrahimi, J Vowles, C Browne, J McCullagh, WS James FEBS letters 594 (10), 1631-1644, 2020 | 29 | 2020 |
Mechanism of diol dehydration by a promiscuous radical‐SAM enzyme homologue of the antiviral enzyme viperin (RSAD2) K Honarmand Ebrahimi, JS Rowbotham, J McCullagh, WS James ChemBioChem 21, 2020 | 28 | 2020 |
The amyloid precursor protein (APP) does not have a ferroxidase site in its E2 domain K Honarmand Ebrahimi, C Dienemann, S Hoefgen, ME Than, ... PLoS One 8 (8), e72177, 2013 | 27 | 2013 |
Inhibition and stimulation of formation of the ferroxidase center and the iron core in Pyrococcus furiosus ferritin K Honarmand Ebrahimi, PL Hagedoorn, WR Hagen JBIC Journal of Biological Inorganic Chemistry 15, 1243-1253, 2010 | 24 | 2010 |
Ion-exchange chromatography coupled to mass spectrometry in life science, environmental, and medical research JB Ngere, KH Ebrahimi, R Williams, E Pires, J Walsby-Tickle, ... Analytical Chemistry 95 (1), 152-166, 2023 | 23 | 2023 |
A novel mechanism of iron-core formation by Pyrococcus furiosus archaeoferritin, a member of an uncharacterized branch of the ferritin-like superfamily KH Ebrahimi, PL Hagedoorn, L van der Weel, PDEM Verhaert, WR Hagen JBIC Journal of Biological Inorganic Chemistry 17, 975-985, 2012 | 23 | 2012 |