Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma CA Clark, HB Gupta, G Sareddy, S Pandeswara, S Lao, B Yuan, JM Drerup, A ... Cancer Research 76 (23), 6964-74, 2016 | 385 | 2016 |
Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer HB Gupta, CA Clark, B Yuan, G Sareddy, S Pandeswara, AS Padron, ... Signal transduction and targeted therapy 1 (1), 1-9, 2016 | 116 | 2016 |
Adipose PD-L1 Modulates PD-1/PD-L1 Checkpoint Blockade Immunotherapy Efficacy in Breast Cancer Harshita B. Gupta, Bogang Wu, Xiujie Sun, Bin Yuan, Jingwei Li, Fei Ge ... OncoImmunology, 2018 | 86 | 2018 |
Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction P Shivshankar, GV Halade, C Calhoun, GP Escobar, AJ Mehr, F Jimenez, C ... Journal of Molecular and Cellular Cardiology 76, 84-93, 2014 | 85 | 2014 |
A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B-and T-cell malignancies M Ortega, H Bhatnagar, AP Lin, L Wang, JC Aster, H Sill, RCT Aguiar Leukemia 29 (4), 968-976, 2015 | 76 | 2015 |
A phosphodiesterase 4B-dependent interplay between tumor cells and the microenvironment regulates angiogenesis in B-cell lymphoma AN Suhasini, L Wang, KN Holder, AP Lin, H Bhatnagar, SW Kim, ... Leukemia 30 (3), 617-626, 2016 | 63 | 2016 |
Tumor cell-intrinsic CD274/PD-L1: A novel metabolic balancing act with clinical potential CA Clark, HB Gupta, TJ Curiel Autophagy 13 (5), 987-988, 2017 | 53 | 2017 |
Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model Á Padrón, V Hurez, HB Gupta, CA Clark, SL Pandeswara, B Yuan, ... Experimental gerontology 105, 146-154, 2018 | 39 | 2018 |
Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy D Zhang, RM Reyes, E Osta, S Kari, HB Gupta, AS Padron, ... Cancer medicine 10 (6), 2137-2152, 2021 | 37 | 2021 |
CD122-Selective IL2 complexes reduce immunosuppression, promote Treg fragility, and sensitize tumor response to PD-L1 blockade JM Drerup, Y Deng, SL Pandeswara, ÁS Padrón, RM Reyes, X Zhang, ... Cancer research 80 (22), 5063-5075, 2020 | 34 | 2020 |
Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer B Yuan, L Cheng, K Gupta, H-C Chiang, HB Gupta, GR Sareddy, D Wang, K ... Oncotarget 7, 42585-42597, 2016 | 23 | 2016 |
Serum and organ‐associated anti‐hemoglobin humoral autoreactivity: Association with anti‐Sm responses and inflammation H Bhatnagar, S Kala, L Sharma, S Jain, KS Kim, R Pal European journal of immunology 41 (2), 537-548, 2011 | 19 | 2011 |
CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation RM Reyes, Y Deng, D Zhang, N Ji, N Mukherjee, K Wheeler, HB Gupta, ... Journal for Immunotherapy of cancer 9 (4), 2021 | 15 | 2021 |
PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner B Wu, X Sun, B Yuan, F Ge, HB Gupta, HC Chiang, J Li, Y Hu, TJ Curiel, ... International Journal of Biological Sciences 16 (9), 1526, 2020 | 15 | 2020 |
Immune checkpoint expression and relationships to anti‐PD‐L1 immune checkpoint blockade cancer immunotherapy efficacy in aged versus young mice MG Garcia, Y Deng, C Murray, RM Reyes, A Padron, H Bai, A Kancharla, ... Aging and cancer 3 (1), 68-83, 2022 | 13 | 2022 |
DNA deamination is required for human APOBEC3A-driven hepatocellular carcinoma in vivo JA Naumann, PP Argyris, MA Carpenter, HB Gupta, Y Chen, NA Temiz, ... International journal of molecular sciences 24 (11), 9305, 2023 | 11 | 2023 |
Tumor cell-intrinsic programmed death protein 1 expression and induction in human cancer cell lines E Osta, HB Gupta, D Zhang, A Kornepati, CA Clark, TJ Curiel The Journal of Immunology 200 (1_Supplement), 178.33-178.33, 2018 | 4 | 2018 |
Tumor B7-H1 regulates cancer stem cell generation and virulence HB Gupta, V Hurez, CA Clark, GR Sareddy, R Vadlamudi, R Li, TJ Curiel The Journal of Immunology 196 (1 Supplement), 72.3-72.3, 2016 | 4 | 2016 |
900 Depleting non-canonical, cell-intrinsic PD-L1 signals induces synthetic lethality to small molecule DNA damage response inhibitors in an immune independent and dependent manner A Kornepati, C Murray, B Avalos, C Rogers, K Ramkumar, H Gupta, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | 2 | 2021 |
Adipocyte PD-L1 suppresses anti-tumor immune response and promotes breast cancer progression B Wu, X Sun, HB Gupta, B Yuan, HC Chiang, Y Hu, TJ Curiel, R Li The Journal of Immunology 204 (1_Supplement), 165.24-165.24, 2020 | 2 | 2020 |