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Ryan Staupe
Ryan Staupe
在 pennmedicine.upenn.edu 的电子邮件经过验证
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引用次数
年份
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ...
Nature 545 (7652), 60-65, 2017
14992017
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
O Khan, JR Giles, S McDonald, S Manne, SF Ngiow, KP Patel, MT Werner, ...
Nature 571 (7764), 211-218, 2019
11492019
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ...
Nature 509 (7498), 55-62, 2014
7862014
TCF-1-centered transcriptional network drives an effector versus exhausted CD8 T cell-fate decision
Z Chen, Z Ji, SF Ngiow, S Manne, Z Cai, AC Huang, J Johnson, ...
Immunity 51 (5), 840-855. e5, 2019
5162019
Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody
D Corti, J Misasi, S Mulangu, DA Stanley, M Kanekiyo, S Wollen, ...
Science 351 (6279), 1339-1342, 2016
4072016
Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16
M Pancera, S Shahzad-ul-Hussan, NA Doria-Rose, JS McLellan, ...
Nature structural & molecular biology 20 (7), 804-813, 2013
3482013
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
IS Georgiev, NA Doria-Rose, T Zhou, Y Do Kwon, RP Staupe, S Moquin, ...
Science 340 (6133), 751-756, 2013
2582013
New member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency
NA Doria-Rose, JN Bhiman, RS Roark, CA Schramm, J Gorman, ...
Journal of virology 90 (1), 76-91, 2016
2422016
Cutting edge: B cell–intrinsic T-bet expression is required to control chronic viral infection
BE Barnett, RP Staupe, PM Odorizzi, O Palko, VT Tomov, AE Mahan, ...
The Journal of Immunology 197 (4), 1017-1022, 2016
1702016
A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies
NA Doria-Rose, I Georgiev, S O'Dell, GY Chuang, RP Staupe, ...
Journal of virology 86 (15), 8319-8323, 2012
992012
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
JR Giles, SF Ngiow, S Manne, AE Baxter, O Khan, P Wang, R Staupe, ...
Nature immunology 23 (11), 1600-1613, 2022
842022
Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells
LM McLane, SF Ngiow, Z Chen, J Attanasio, S Manne, G Ruthel, JE Wu, ...
Cell reports 35 (6), 2021
742021
PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine
RS Herati, DA Knorr, LA Vella, LV Silva, L Chilukuri, SA Apostolidis, ...
Nature immunology 23 (8), 1183-1192, 2022
452022
In vitro modeling of CD8+ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40
JE Wu, S Manne, SF Ngiow, AE Baxter, H Huang, E Freilich, ML Clark, ...
Science Immunology 8 (86), eade3369, 2023
92023
Chronic viral infection promotes early germinal center exit of B cells and impaired antibody development
RP Staupe, LA Vella, S Manne, JR Giles, W Meng, RS Herati, O Khan, ...
BioRxiv, 849844, 2019
72019
Single cell multi-omic reference atlases of non-human primate immune tissues reveals CD102 as a biomarker for long-lived plasma cells
RP Staupe, KE Lodge, N Thambi, D Toole, AM Tamburino, D Chang, ...
Communications Biology 5 (1), 1399, 2022
62022
Longitudinal single cell transcriptional and epigenetic mapping of effector, memory, and exhausted CD8 T cells reveals shared biological circuits across distinct cell fates
JR Giles, SF Ngiow, S Manne, AE Baxter, O Khan, P Wang, R Staupe, ...
bioRxiv, 2022.03. 27.485974, 2022
62022
A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies
NA Doria-Rose, I Georgiev, RP Staupe, S O'Dell, G Chuang, J Gorman, ...
Retrovirology 9, 1-1, 2012
12012
Regulation of effective vs. ineffective B cell responses to chronic viral infections.
RP Staupe, EJ Wherry
The Journal of Immunology 196 (1_Supplement), 147.2-147.2, 2016
2016
Structural Characterization of Potent, Longitudinally-Defined HIV-1 V1/V2-Directed Antibodies
J Gorman, N Doria-Rose, CA Schramm, PL Moore, M Pancera, Y Yang, ...
AIDS RESEARCH AND HUMAN RETROVIRUSES 29 (11), A12-A12, 2013
2013
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