| 5'-Triphosphate RNA is the ligand for RIG-I V Hornung, J Ellegast, S Kim, K Brzózka, A Jung, H Kato, H Poeck, ... science 314 (5801), 994-997, 2006 | 3143 | 2006 |
| Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice Y Saito, JM Ellegast, A Rafiei, Y Song, D Kull, M Heikenwalder, ... Blood, The Journal of the American Society of Hematology 128 (14), 1829-1833, 2016 | 81 | 2016 |
| Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33 N Azoitei, CM Hoffmann, JM Ellegast, CR Ball, K Obermayer, U Gößele, ... Journal of Experimental Medicine 209 (4), 697-711, 2012 | 77 | 2012 |
| RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia S Rudat, A Pfaus, YY Cheng, J Holtmann, JM Ellegast, C Buehler, ... Leukemia 32 (10), 2189-2202, 2018 | 65 | 2018 |
| Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2 JR LaRochelle, M Fodor, JM Ellegast, X Liu, V Vemulapalli, M Mohseni, ... Bioorganic & medicinal chemistry 25 (24), 6479-6485, 2017 | 54 | 2017 |
| inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice JM Ellegast, PJ Rauch, LV Kovtonyuk, R Müller, U Wagner, Y Saito, ... Blood, The Journal of the American Society of Hematology 128 (17), 2130-2134, 2016 | 46 | 2016 |
| MPL expression on AML blasts predicts peripheral blood neutropenia and thrombocytopenia PJ Rauch, JM Ellegast, CC Widmer, K Fritsch, JS Goede, PJM Valk, ... Blood, The Journal of the American Society of Hematology 128 (18), 2253-2257, 2016 | 44 | 2016 |
| Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor B Roux, C Vaganay, JD Vargas, G Alexe, C Benaksas, B Pardieu, ... Science translational medicine 13 (587), eabg1168, 2021 | 38 | 2021 |
| Resistance mechanisms to SYK inhibition in acute myeloid leukemia A Cremer, JM Ellegast, G Alexe, ES Frank, L Ross, SH Chu, Y Pikman, ... Cancer discovery 10 (2), 214-231, 2020 | 34 | 2020 |
| Unleashing cell-intrinsic inflammation as a strategy to kill AML blasts JM Ellegast, G Alexe, A Hamze, S Lin, HJ Uckelmann, PJ Rauch, ... Cancer Discovery 12 (JULY), 1760–81, 2022 | 25 | 2022 |
| The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma DY Lu, JM Ellegast, KN Ross, CF Malone, S Lin, NW Mabe, NV Dharia, ... Nature Cell Biology 25 (2), 285-297, 2023 | 22 | 2023 |
| A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia T Harada, Y Heshmati, J Kalfon, MW Perez, JX Ferrucio, J Ewers, ... Genes & development 36 (5-6), 368-389, 2022 | 16 | 2022 |
| Generation of humanized mice for analysis of human dendritic cells Y Saito, JM Ellegast, MG Manz Dendritic Cell Protocols, 309-320, 2016 | 16 | 2016 |
| PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy PG Miller, AS Sperling, C Mayerhofer, ME McConkey, JM Ellegast, ... Blood 142 (24), 2079-2091, 2023 | 11 | 2023 |
| Metastasis of osteosarcoma after 16 years J Ellegast, TFE Barth, M Schulte, SS Bielack, M Schmid, ... Journal of Clinical Oncology 29 (3), e62-e66, 2011 | 9 | 2011 |
| Resistance mechanisms to SYK inhibition in acute myeloid leukemia. Cancer Discov. 2019 doi: 10.1158/2159-8290 A Cremer, JM Ellegast, G Alexe, ES Frank, L Ross, SH Chu, Y Pikman, ... CD-19-0209.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 7 | |
| The RET receptor tyrosine kinase promotes acute myeloid leukemia through protection of FLT3-ITD mutants from autophagic degradation S Rudat, A Pfaus, C Bühler, S Rabe, L Bullinger, S Gröschel, SM Sykes, ... Blood 128 (22), 2849, 2016 | 4 | 2016 |
| Diagnostic et traitement de la leucémie myéloïde aiguë JM Ellegast, B Gerber, MG Manz Forum Médical Suisse‒Swiss Medical Forum 13, 2013 | 4 | 2013 |
| Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops T Harada, J Kalfon, MW Perez, K Eagle, FD Braes, R Batley, Y Heshmati, ... bioRxiv, 2023 | 3 | 2023 |
| ΜΙSΤRG mice support good-risk AML engraftment JM Ellegast, Y Saito, RA Flavell, MG Manz Blood, The Journal of the American Society of Hematology 124 (21), 3808-3808, 2014 | 3 | 2014 |
