Transforming growth factor-beta 1 delivery from microporous scaffolds decreases inflammation post-implant and enhances function of transplanted islets JMH Liu, J Zhang, X Zhang, KA Hlavaty, CF Ricci, JN Leonard, LD Shea, ... Biomaterials 80, 11-19, 2016 | 119 | 2016 |
Nanoparticle delivery of donor antigens for transplant tolerance in allogeneic islet transplantation J Bryant, KA Hlavaty, X Zhang, WT Yap, L Zhang, LD Shea, X Luo Biomaterials 35 (31), 8887-8894, 2014 | 101 | 2014 |
Tolerance induction using nanoparticles bearing HY peptides in bone marrow transplantation KA Hlavaty, DP McCarthy, E Saito, WT Yap, SD Miller, LD Shea Biomaterials 76, 1-10, 2016 | 54 | 2016 |
Enhancing human islet transplantation by localized release of trophic factors from PLG scaffolds KA Hlavaty, RF Gibly, X Zhang, CB Rives, JG Graham, WL Lowe Jr, X Luo, ... American Journal of Transplantation 14 (7), 1523-1532, 2014 | 54 | 2014 |
Cellular and molecular targeting for nanotherapeutics in transplantation tolerance KA Hlavaty, X Luo, LD Shea, SD Miller Clinical Immunology 160 (1), 14-23, 2015 | 30 | 2015 |
Microfluidic squeezing enables MHC class I antigen presentation by diverse immune cells to elicit CD8+ T cell responses with antitumor activity MG Booty, KA Hlavaty, A Stockmann, EI Ozay, C Smith, L Tian, E How, ... The Journal of Immunology 208 (4), 929-940, 2022 | 13 | 2022 |
Intracellular delivery of biomolecules to modify immune response S Loughhead, L Talarico, A Vicente-Suarez, M Booty, H Bernstein, ... US Patent App. 16/980,339, 2021 | 3 | 2021 |
Methods for treating hpv-associated diseases S Loughhead, L Talarico, A Vicente-Suarez, M Booty, H Bernstein, ... US Patent App. 16/980,341, 2021 | 3 | 2021 |
169 Microfluidics cell squeezing enables human PBMCs as drivers of antigen-specific CD8 T responses across broad range of antigens for diverse clinical applications M Maloney, S Loughhead, A Ramakrishnan, C Smith, A Venkitaraman, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 3 | 2020 |
SQZing cells to rapidly generate antigen presenting cells (APC) for solid tumor immune therapies with efficient, scalable manufacturing SM Loughhead, MG Booty, K Hlavaty, A Vicente-Suarez, K Blagovic, ... Annals of Oncology 29, x13, 2018 | 3 | 2018 |
Engineering a new generation of cell therapies for solid tumor oncology using the SQZ platform KA Hlavaty, MG Booty, S Loughhead, K Blagovic, A Vicente-Suarez, ... Cancer Research 79 (13_Supplement), 3187-3187, 2019 | 2 | 2019 |
Intracellular delivery of biomolecules to enhance antigen presenting cell function H Bernstein, M Booty, L Cassereau, J Chow, K Hlavaty, S Loughhead, ... US Patent App. 17/282,709, 2021 | 1 | 2021 |
In Vivo Delivery of a CD20 CAR Using a CD8-Targeted Fusosome in Southern Pig-Tail Macaques (M. nemestrina) Results in B Cell Depletion J Cunningham, S Chandra, A Emmanuel, A Mazzarelli, C Passaro, ... Blood 138, 2769, 2021 | 1 | 2021 |
Abstract LB105: In vivo CAR T therapy: targeted in vivo gene delivery of a CAR using a CD8-specific fusogen results in tumor eradication A Emmanuel, P Cruite, H Ennajdaoui, C Passaro, P Baldwin, V Duback, ... Cancer Research 81 (13_Supplement), LB105-LB105, 2021 | 1 | 2021 |
Biomaterial Approaches for Immunomodulation to Enhance Transplantation Tolerance KA Hlavaty Northwestern University, 2015 | 1 | 2015 |
DELIVERY OF BIOMOLECULES TO PBMCs TO MODIFY AN IMMUNE RESPONSE AR Sharei, H Bernstein, S Loughhead, M Booty, K Blagovic, K Hlavaty, ... US Patent App. 18/318,842, 2024 | | 2024 |
Delivery of biomolecules to PBMCs to modify an immune response AR Sharei, H Bernstein, S Loughhead, M Booty, K Blagovic, K Hlavaty, ... US Patent 11,692,168, 2023 | | 2023 |
Formulations of pbmcs H Bernstein, S Loughhead, M Booty, K Hlavaty, T Abdeljawad, M Dadgar, ... US Patent App. 17/563,764, 2022 | | 2022 |
Fusosome-Targeted Gene Transfer to Human Hepatocytes M Stoppato, K Trudeau, K Sullivan, A Mazzarelli, C Cote, P Cruite, ... MOLECULAR THERAPY 30 (4), 415-415, 2022 | | 2022 |
Retargeted" Fusosomes" for In Vivo Delivery to T Cells P Cruite, Z Frye, S Amatya, B Dolinski, B Granger, C Ciarlo, H Ennajdaoui, ... MOLECULAR THERAPY 30 (4), 504-504, 2022 | | 2022 |