Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance P Gagnon, R Nian, J Lee, L Tan, SMA Latiff, CL Lim, C Chuah, X Bi, ... Journal of Chromatography A 1340, 68-78, 2014 | 75 | 2014 |
Bioreduction with efficient recycling of NADPH by coupled permeabilized microorganisms W Zhang, K O'Connor, DIC Wang, Z Li Applied and Environmental Microbiology 75 (3), 687-694, 2009 | 62 | 2009 |
Advance chromatin extraction improves capture performance of protein A affinity chromatography R Nian, W Zhang, L Tan, J Lee, X Bi, Y Yang, HT Gan, P Gagnon Journal of Chromatography A 1431, 1-7, 2016 | 58 | 2016 |
Reversible clustering of magnetic nanobiocatalysts for high-performance biocatalysis and easy catalyst recycling TPN Ngo, W Zhang, W Wang, Z Li Chemical Communications 48 (38), 4585-4587, 2012 | 49 | 2012 |
Current trends and challenges in the downstream purification of bispecific antibodies SW Chen, W Zhang Antibody therapeutics 4 (2), 73-88, 2021 | 43 | 2021 |
Downstream processing of recombinant human insulin and its analogues production from E. coli inclusion bodies YY Siew, W Zhang Bioresources and Bioprocessing 8, 1-27, 2021 | 34 | 2021 |
Regio‐ and Stereoselective Biohydroxylations with a Recombinant Escherichia coli Expressing P450pyr Monooxygenase of Sphingomonas Sp. HXN‐200 W Zhang, WL Tang, Z Wang, Z Li Advanced Synthesis & Catalysis 352 (18), 3380-3390, 2010 | 28 | 2010 |
A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins KH Sim, LCY Liu, HT Tan, K Tan, D Ng, W Zhang, Y Yang, S Tate, X Bi Scientific Data 7 (1), 263, 2020 | 23 | 2020 |
Concurrent oxidations with tandem biocatalysts in one pot: green, selective and clean oxidations of methylene groups to ketones W Zhang, WL Tang, DIC Wang, Z Li Chemical Communications 47 (11), 3284-3286, 2011 | 23 | 2011 |
Investigation of the effect of salt additives in Protein L affinity chromatography for the purification of tandem single-chain variable fragment bispecific antibodies SW Chen, D Tan, YS Yang, W Zhang MAbs 12 (1), 1718440, 2020 | 21 | 2020 |
A simple and efficient purification platform for monoclonal antibody production based on chromatin-directed cell culture clarification integrated with precipitation and void … Q Chen, SMA Latiff, P Toh, X Peng, A Hoi, M Xian, H Zhang, R Nian, ... Journal of Biotechnology 236, 128-140, 2016 | 15 | 2016 |
Impact of signal peptides on Furin‐2A mediated monoclonal antibody secretion in CHO cells J Lin, SH Neo, SCL Ho, JHM Yeo, T Wang, W Zhang, X Bi, SH Chao, ... Biotechnology Journal 12 (9), 1700268, 2017 | 14 | 2017 |
Excellent removal of knob-into-hole bispecific antibody byproducts and impurities in a single-capture chromatography SW Chen, KM Hoi, FB Mahfut, Y Yang, W Zhang Bioresources and Bioprocessing 9 (1), 72, 2022 | 8 | 2022 |
Effective flow-through polishing strategies for knob-into-hole bispecific antibodies SW Chen, KM Hoi, FB Mahfut, Y Yang, W Zhang Bioresources and Bioprocessing 9 (1), 98, 2022 | 5 | 2022 |
Understanding and controlling the molecular mechanisms of protein aggregation in mAb therapeutics KT Pang, YS Yang, W Zhang, YS Ho, P Sormanni, TCT Michaels, I Walsh, ... Biotechnology Advances 67, 108192, 2023 | 4 | 2023 |
Histone-dependent IgG conservation in octanoic acid precipitation and its mechanism Q Chen, P Toh, Y Sun, SMA Latiff, A Hoi, M Xian, H Zhang, R Nian, ... Applied microbiology and biotechnology 100, 9933-9941, 2016 | 4 | 2016 |
New and efficient purification process for recombinant human insulin produced in Escherichia coli YY Siew, A Rai, HB Pek, DSW Ow, W Zhang Applied Microbiology and Biotechnology 105, 9137-9151, 2021 | 3 | 2021 |
Development of a T cell-redirecting bispecific antibody targeting B-cell maturation antigen for the suppression of multiple myeloma cell growth J Huo, Y Huang, Z Zheng, XN Tay, FB Mahfut, W Zhang, KP Lam, Y Yang, ... Antibody therapeutics 5 (2), 138-149, 2022 | 2 | 2022 |
A new and simplified anion exchange chromatographic process for the purification of cell-grown influenza A H1N1 virus DT Ta, KL Chu, NIB Soonaan, C Chin, SK Ng, W Zhang Separation and Purification Technology 263, 118412, 2021 | 2 | 2021 |
Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies HP Loh, FB Mahfut, SW Chen, Y Huang, J Huo, W Zhang, KP Lam, S Xu, ... Mabs 15 (1), 2231129, 2023 | 1 | 2023 |