Therapeutic opportunities within the DNA damage response LH Pearl, AC Schierz, SE Ward, B Al-Lazikani, FMG Pearl Nature Reviews Cancer 15 (3), 166-180, 2015 | 541 | 2015 |
Comprehensive medicinal chemistry III S Chackalamannil, D Rotella, S Ward Elsevier, 2017 | 138 | 2017 |
Mesoproterozoic intraplate magmatism in the Kalahari Craton: a review RE Hanson, RE Harmer, TG Blenkinsop, DS Bullen, IWD Dalziel, ... Journal of African Earth Sciences 46 (1-2), 141-167, 2006 | 124 | 2006 |
Synthesis of polyprenylated acylphloroglucinols using bridgehead lithiation: the total synthesis of racemic clusianone and a formal synthesis of racemic garsubellin A NM Ahmad, V Rodeschini, NS Simpkins, SE Ward, AJ Blake The Journal of organic chemistry 72 (13), 4803-4815, 2007 | 102 | 2007 |
A New synthetic route to 1, 3, 5‐triamino‐2, 4, 6‐trinitrobenzene (TATB) AJ Bellamy, SJ Ward, P Golding Propellants, Explosives, Pyrotechnics: An International Journal Dealing with …, 2002 | 97 | 2002 |
Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan C Meisenberg, DC Gilbert, A Chalmers, V Haley, S Gollins, SE Ward, ... Molecular cancer therapeutics 14 (2), 575-585, 2015 | 85 | 2015 |
A proposed new definition and measurement of the shielding effect of equipment enclosures AC Marvin, JF Dawson, S Ward, L Dawson, J Clegg, A Weissenfeld IEEE Transactions on Electromagnetic Compatibility 46 (3), 459-468, 2004 | 85 | 2004 |
Challenges for and current status of research into positive modulators of AMPA receptors SE Ward, BD Bax, M Harries British journal of pharmacology 160 (2), 181-190, 2010 | 82 | 2010 |
Factors determining the mortality and morbidity in hepatic injuries. Analysis of 108 cases. JS Aldrete, NB Halpern, S Ward, JO Wright Annals of Surgery 189 (4), 466, 1979 | 72 | 1979 |
The handbook of medicinal chemistry: principles and practice A Davis, SE Ward Royal Society of Chemistry, 2014 | 70 | 2014 |
Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators SE Ward, M Harries, L Aldegheri, NE Austin, S Ballantine, E Ballini, ... Journal of medicinal chemistry 54 (1), 78-94, 2011 | 69 | 2011 |
What does the aromatic ring number mean for drug design? SE Ward, P Beswick Expert opinion on drug discovery 9 (9), 995-1003, 2014 | 67 | 2014 |
Myometrial desensitization after ritodrine infusion SN Caritis, JP Chiao, JJ Moore, SM Ward American Journal of Physiology-Endocrinology and Metabolism 253 (4), E410-E417, 1987 | 67 | 1987 |
Selective cleavage of benzyl ethers MS Congreve, EC Davison, MAM Fuhry, AB Holmes, AN Payne, ... Synlett 1993 (09), 663-664, 1993 | 62 | 1993 |
Fertility in schizophrenia: results from a contemporary US cohort VL Nimgaonkar, SE Ward, H Agarde, N Weston, R Ganguli Acta Psychiatrica Scandinavica 95 (5), 364-369, 1997 | 60 | 1997 |
Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan C Meisenberg, ME Ashour, L El-Shafie, C Liao, A Hodgson, A Pilborough, ... Nucleic acids research 45 (3), 1159-1176, 2017 | 59 | 2017 |
Subtype Selective γ-Aminobutyric Acid Type A Receptor (GABAAR) Modulators Acting at the Benzodiazepine Binding Site: An Update S Maramai, M Benchekroun, SE Ward, JR Atack Journal of medicinal chemistry 63 (7), 3425-3446, 2019 | 57 | 2019 |
Quinoline and quinazoline derivatives having affinity for 5HT1-type receptors M Biagetti, A Falchi, CP Leslie, G Merlo, DA Pizzi, M Rinaldi, LP Stasi, ... US Patent 7,459,456, 2008 | 57 | 2008 |
Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno [3, 2-d] pyrimidine-4-methanone derivatives RJ Gillespie, DR Adams, D Bebbington, K Benwell, IA Cliffe, CE Dawson, ... Bioorganic & medicinal chemistry letters 18 (9), 2916-2919, 2008 | 54 | 2008 |
Discovery of N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator SE Ward, M Harries, L Aldegheri, D Andreotti, S Ballantine, BD Bax, ... Journal of medicinal chemistry 53 (15), 5801-5812, 2010 | 48 | 2010 |