The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease R Bartlett, L Stokes, R Sluyter Pharmacological reviews 66 (3), 638-675, 2014 | 435 | 2014 |
The human P2X7 receptor and its role in innate immunity JS Wiley, R Sluyter, BJ Gu, L Stokes, SJ Fuller Tissue antigens 78 (5), 321-332, 2011 | 250 | 2011 |
Two haplotypes of the P2X7 receptor containing the Ala‐348 to Thr polymorphism exhibit a gain‐of‐function effect and enhanced interleukin‐1β secretion L Stokes, SJ Fuller, R Sluyter, KK Skarratt, BJ Gu, JS Wiley The FASEB Journal 24 (8), 2916-2927, 2010 | 213 | 2010 |
Significance of P2X7 receptor variants to human health and disease R Sluyter, L Stokes Recent Patents on DNA & Gene Sequences (Discontinued) 5 (1), 41-54, 2011 | 179 | 2011 |
Characterization of a selective and potent antagonist of human P2X7 receptors, AZ11645373 L Stokes, LH Jiang, L Alcaraz, J Bent, K Bowers, M Fagura, M Furber, ... British journal of pharmacology 149 (7), 880-887, 2006 | 168 | 2006 |
Genetics of the P2X7 receptor and human disease SJ Fuller, L Stokes, KK Skarratt, BJ Gu, JS Wiley Purinergic signalling 5, 257-262, 2009 | 159 | 2009 |
Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor KR Vaughan, L Stokes, LR Prince, HM Marriott, S Meis, MU Kassack, ... The Journal of Immunology 179 (12), 8544-8553, 2007 | 144 | 2007 |
P2X4 receptor function in the nervous system and current breakthroughs in pharmacology L Stokes, JA Layhadi, L Bibic, K Dhuna, SJ Fountain Frontiers in pharmacology 8, 291, 2017 | 138 | 2017 |
Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major α pore-forming and auxiliary β-subunits L Stokes, J Gordon, G Grafton Journal of Biological Chemistry 279 (19), 19566-19573, 2004 | 110 | 2004 |
Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: this dissociation regulates P2X7 pore formation BJ Gu, C Rathsam, L Stokes, AB McGeachie, JS Wiley American Journal of Physiology-Cell Physiology 297 (2), C430-C439, 2009 | 106 | 2009 |
Calcium channels in lymphocytes G Grafton, L Thwaite Immunology 104 (2), 119, 2001 | 97 | 2001 |
Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism A Bhaskaracharya, P Dao-Ung, I Jalilian, M Spildrejorde, KK Skarratt, ... PloS one 9 (3), e93058, 2014 | 94 | 2014 |
Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures NR Jørgensen, LB Husted, KK Skarratt, L Stokes, CL Tofteng, T Kvist, ... European Journal of Human Genetics 20 (6), 675-681, 2012 | 94 | 2012 |
Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women A Gartland, KK Skarratt, LJ Hocking, C Parsons, L Stokes, NR Jørgensen, ... European Journal of Human Genetics 20 (5), 559-564, 2012 | 86 | 2012 |
P2X receptor characterization and IL‐1/IL‐1Ra release from human endothelial cells HL Wilson, RW Varcoe, L Stokes, KL Holland, SE Francis, SK Dower, ... British journal of pharmacology 151 (1), 96-108, 2007 | 86 | 2007 |
Neonatal overfeeding alters hypothalamic microglial profiles and central responses to immune challenge long-term I Ziko, S De Luca, T Dinan, JM Barwood, L Sominsky, G Cai, R Kenny, ... Brain, behavior, and immunity 41, 32-43, 2014 | 81 | 2014 |
A loss-of-function polymorphism in the human P2X4 receptor is associated with increased pulse pressure L Stokes, K Scurrah, JA Ellis, BA Cromer, KK Skarratt, BJ Gu, SB Harrap, ... Hypertension 58 (6), 1086-1092, 2011 | 72 | 2011 |
Purinergic P2Y2 receptors induce increased MCP-1/CCL2 synthesis and release from rat alveolar and peritoneal macrophages L Stokes, A Surprenant The Journal of Immunology 179 (9), 6016-6023, 2007 | 69 | 2007 |
Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation L Stokes, A Surprenant European journal of immunology 39 (4), 986-995, 2009 | 65 | 2009 |
Understanding the role of P2X7 in affective disorders—are glial cells the major players? L Stokes, SJ Spencer, TA Jenkins Frontiers in cellular neuroscience 9, 258, 2015 | 56 | 2015 |