Epithelial–mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease KA Rygiel, H Robertson, HL Marshall, M Pekalski, L Zhao, TA Booth, ... Laboratory investigation 88 (2), 112-123, 2008 | 305 | 2008 |
Denervation causes fiber atrophy and myosin heavy chain co-expression in senescent skeletal muscle SL Rowan, K Rygiel, FM Purves-Smith, NM Solbak, DM Turnbull, ... PloS one 7 (1), e29082, 2012 | 275 | 2012 |
Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation M Picard, B Jung, F Liang, I Azuelos, S Hussain, P Goldberg, R Godin, ... American journal of respiratory and critical care medicine 186 (11), 1140-1149, 2012 | 235 | 2012 |
Mitochondrial DNA depletion in respiratory chain–deficient p arkinson disease neurons A Grünewald, KA Rygiel, PD Hepplewhite, CM Morris, M Picard, ... Annals of neurology 79 (3), 366-378, 2016 | 232 | 2016 |
The ageing neuromuscular system and sarcopenia: a mitochondrial perspective KA Rygiel, M Picard, DM Turnbull The Journal of physiology 594 (16), 4499-4512, 2016 | 157 | 2016 |
A novel immunofluorescent assay to investigate oxidative phosphorylation deficiency in mitochondrial myopathy: understanding mechanisms and improving diagnosis MC Rocha, JP Grady, A Grünewald, A Vincent, PF Dobson, RW Taylor, ... Scientific reports 5 (1), 15037, 2015 | 130 | 2015 |
Mitochondrial and inflammatory changes in sporadic inclusion body myositis KA Rygiel, J Miller, JP Grady, MC Rocha, RW Taylor, DM Turnbull Neuropathology and applied neurobiology 41 (3), 288-303, 2015 | 103 | 2015 |
Polyfunctional response by ImmTAC (IMCgp100) redirected CD8+ and CD4+ T cells C Boudousquie, G Bossi, JM Hurst, KA Rygiel, BK Jakobsen, NJ Hassan Immunology 152 (3), 425-438, 2017 | 75 | 2017 |
An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules J Harper, KJ Adams, G Bossi, DE Wright, AR Stacey, N Bedke, ... PloS one 13 (10), e0205491, 2018 | 66 | 2018 |
Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis KA Rygiel, HA Tuppen, JP Grady, A Vincent, EL Blakely, AK Reeve, ... Nucleic acids research 44 (11), 5313-5329, 2016 | 55 | 2016 |
Subcellular origin of mitochondrial DNA deletions in human skeletal muscle AE Vincent, HS Rosa, K Pabis, C Lawless, C Chen, A Grünewald, ... Annals of neurology 84 (2), 289-301, 2018 | 54 | 2018 |
Respiratory chain deficiency in aged spinal motor neurons KA Rygiel, JP Grady, DM Turnbull Neurobiology of aging 35 (10), 2230-2238, 2014 | 50 | 2014 |
Mitochondrial dysfunction in myofibrillar myopathy AE Vincent, JP Grady, MC Rocha, CL Alston, KA Rygiel, R Barresi, ... Neuromuscular Disorders 26 (10), 691-701, 2016 | 46 | 2016 |
Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo OM Russell, I Fruh, PK Rai, D Marcellin, T Doll, A Reeve, M Germain, ... Scientific reports 8 (1), 1799, 2018 | 41 | 2018 |
Triplex real-time PCR–an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells KA Rygiel, JP Grady, RW Taylor, HAL Tuppen, DM Turnbull Scientific reports 5 (1), 9906, 2015 | 37 | 2015 |
Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue A Grünewald, NZ Lax, MC Rocha, AK Reeve, PD Hepplewhite, KA Rygiel, ... Journal of neuroscience methods 232, 143-149, 2014 | 37 | 2014 |
Dysferlin mutations and mitochondrial dysfunction AE Vincent, HS Rosa, CL Alston, JP Grady, KA Rygiel, MC Rocha, ... Neuromuscular Disorders 26 (11), 782-788, 2016 | 36 | 2016 |
Naked mole-rats maintain healthy skeletal muscle and Complex IV mitochondrial enzyme function into old age EA Stoll, N Karapavlovic, H Rosa, M Woodmass, K Rygiel, K White, ... Aging (Albany NY) 8 (12), 3468, 2016 | 29 | 2016 |
Skeletal muscle mitochondrial oxidative phosphorylation function in idiopathic pulmonary arterial hypertension: in vivo and in vitro study S Sithamparanathan, MC Rocha, JD Parikh, KA Rygiel, G Falkous, ... Pulmonary circulation 8 (2), 2045894018768290, 2018 | 18 | 2018 |
T cell‐mediated biliary epithelial‐to‐mesenchymal transition in liver allograft rejection KA Rygiel, H Robertson, JDP Willet, JG Brain, AD Burt, DEJ Jones, ... Liver Transplantation 16 (5), 567-576, 2010 | 18 | 2010 |