Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease TF Outeiro, E Kontopoulos, SM Altmann, I Kufareva, KE Strathearn, ... science 317 (5837), 516-519, 2007 | 1267 | 2007 |
Structure of the CCR5 chemokine receptor–HIV entry inhibitor maraviroc complex Q Tan, Y Zhu, J Li, Z Chen, GW Han, I Kufareva, T Li, L Ma, G Fenalti, J Li, ... Science 341 (6152), 1387-1390, 2013 | 821 | 2013 |
Methods of protein structure comparison I Kufareva, R Abagyan Homology modeling: Methods and protocols, 231-257, 2012 | 635 | 2012 |
The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer M O'hayre, J Vázquez-Prado, I Kufareva, EW Stawiski, TM Handel, ... Nature reviews cancer 13 (6), 412-424, 2013 | 577 | 2013 |
Crystal structure of the human cannabinoid receptor CB1 T Hua, K Vemuri, M Pu, L Qu, GW Han, Y Wu, S Zhao, W Shui, S Li, ... Cell 167 (3), 750-762. e14, 2016 | 574 | 2016 |
Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine L Qin, I Kufareva, LG Holden, C Wang, Y Zheng, C Zhao, G Fenalti, H Wu, ... Science 347 (6226), 1117-1122, 2015 | 419 | 2015 |
Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment I Kufareva, M Rueda, V Katritch, RC Stevens, R Abagyan Structure 19 (8), 1108-1126, 2011 | 343 | 2011 |
Structure-Based Discovery of Novel Chemotypes for Adenosine A2A Receptor Antagonists V Katritch, VP Jaakola, JR Lane, J Lin, AP IJzerman, M Yeager, I Kufareva, ... Journal of medicinal chemistry 53 (4), 1799-1809, 2010 | 291 | 2010 |
Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists Y Zheng, L Qin, NVO Zacarías, H de Vries, GW Han, M Gustavsson, ... Nature 540 (7633), 458-461, 2016 | 283 | 2016 |
Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies I Kufareva, CL Salanga, TM Handel Immunology and cell biology 93 (4), 372-383, 2015 | 252 | 2015 |
Type-II kinase inhibitor docking, screening, and profiling using modified structures of active kinase states I Kufareva, R Abagyan Journal of medicinal chemistry 51 (24), 7921-7932, 2008 | 234 | 2008 |
Four-dimensional docking: a fast and accurate account of discrete receptor flexibility in ligand docking G Bottegoni, I Kufareva, M Totrov, R Abagyan Journal of medicinal chemistry 52 (2), 397-406, 2009 | 215 | 2009 |
3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis T Hayashi, JH Mo, X Gong, C Rossetto, A Jang, L Beck, GI Elliott, ... Proceedings of the National Academy of Sciences 104 (47), 18619-18624, 2007 | 212 | 2007 |
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges I Kufareva, V Katritch, RC Stevens, R Abagyan Structure 22 (8), 1120-1139, 2014 | 183 | 2014 |
Pocketome: an encyclopedia of small-molecule binding sites in 4D I Kufareva, AV Ilatovskiy, R Abagyan Nucleic acids research 40 (D1), D535-D540, 2012 | 179 | 2012 |
Structure of CC chemokine receptor 5 with a potent chemokine antagonist reveals mechanisms of chemokine recognition and molecular mimicry by HIV Y Zheng, GW Han, R Abagyan, B Wu, RC Stevens, V Cherezov, ... Immunity 46 (6), 1005-1017. e5, 2017 | 175 | 2017 |
PIER: protein interface recognition for structural proteomics I Kufareva, L Budagyan, E Raush, M Totrov, R Abagyan Proteins: Structure, Function, and Bioinformatics 67 (2), 400-417, 2007 | 144 | 2007 |
Viral infection controlled by a calcium-dependent lipid-binding module in ALIX C Bissig, M Lenoir, MC Velluz, I Kufareva, R Abagyan, M Overduin, ... Developmental cell 25 (4), 364-373, 2013 | 129 | 2013 |
Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices MP Wescott, I Kufareva, C Paes, JR Goodman, Y Thaker, BA Puffer, ... Proceedings of the National Academy of Sciences 113 (35), 9928-9933, 2016 | 128 | 2016 |
Structural basis of ligand interaction with atypical chemokine receptor 3 M Gustavsson, L Wang, N Van Gils, BS Stephens, P Zhang, TJ Schall, ... Nature communications 8 (1), 14135, 2017 | 107 | 2017 |