Highly efficient endogenous human gene correction using designed zinc-finger nucleases FD Urnov, JC Miller, YL Lee, CM Beausejour, JM Rock, S Augustus, ... Nature 435 (7042), 646-651, 2005 | 2204 | 2005 |
Reversal of human cellular senescence: roles of the p53 and p16 pathways CM Beauséjour, A Krtolica, F Galimi, M Narita, SW Lowe, P Yaswen, ... The EMBO journal, 2003 | 1718 | 2003 |
An improved zinc-finger nuclease architecture for highly specific genome editing JC Miller, MC Holmes, J Wang, DY Guschin, YL Lee, I Rupniewski, ... Nature biotechnology 25 (7), 778-785, 2007 | 1506 | 2007 |
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery A Lombardo, P Genovese, CM Beausejour, S Colleoni, YL Lee, KA Kim, ... Nature biotechnology 25 (11), 1298-1306, 2007 | 1160 | 2007 |
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation M Fumagalli, F Rossiello, M Clerici, S Barozzi, D Cittaro, JM Kaplunov, ... Nature cell biology 14 (4), 355-365, 2012 | 899 | 2012 |
L1 drives IFN in senescent cells and promotes age-associated inflammation M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ... Nature 566 (7742), 73-78, 2019 | 841 | 2019 |
Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence JP Coppé, K Kauser, J Campisi, CM Beauséjour Journal of Biological Chemistry 281 (40), 29568-29574, 2006 | 694 | 2006 |
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion F Rodier, DP Muñoz, R Teachenor, V Chu, O Le, D Bhaumik, JP Coppé, ... Journal of cell science 124 (1), 68-81, 2011 | 613 | 2011 |
Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1 K Itahana, Y Zou, Y Itahana, JL Martinez, C Beausejour, JJL Jacobs, ... Molecular and cellular biology 23 (1), 389-401, 2003 | 586 | 2003 |
A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen JP Coppe, CK Patil, F Rodier, A Krtolica, CM Beausejour, S Parrinello, ... PloS one 5 (2), e9188, 2010 | 507 | 2010 |
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes AR Davalos, M Kawahara, GK Malhotra, N Schaum, J Huang, U Ved, ... Journal of Cell Biology 201 (4), 613-629, 2013 | 441 | 2013 |
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis P Sapieha, M Sirinyan, D Hamel, K Zaniolo, JS Joyal, JH Cho, JC Honoré, ... Nature medicine 14 (10), 1067-1076, 2008 | 416 | 2008 |
TIN2 mediates functions of TRF2 at human telomeres S Kim, C Beausejour, AR Davalos, P Kaminker, SJ Heo, J Campisi Journal of biological chemistry 279 (42), 43799-43804, 2004 | 323 | 2004 |
Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A JS Joyal, N Sitaras, F Binet, JC Rivera, A Stahl, K Zaniolo, Z Shao, ... Blood, The Journal of the American Society of Hematology 117 (22), 6024-6035, 2011 | 203 | 2011 |
Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status ONL Le, F Rodier, F Fontaine, JP Coppe, J Campisi, J DeGregori, ... Aging cell 9 (3), 398-409, 2010 | 190 | 2010 |
Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming S Selleri, P Bifsha, S Civini, C Pacelli, MM Dieng, W Lemieux, P Jin, ... Oncotarget 7 (21), 30193, 2016 | 159 | 2016 |
Balancing regeneration and cancer CM Beausejour, J Campisi Nature 443 (7110), 404-405, 2006 | 140 | 2006 |
Bone marrow-derived cells: the influence of aging and cellular senescence C Beausejour Bone marrow-derived progenitors, 67-88, 2007 | 108 | 2007 |
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition S Crespo-Garcia, PR Tsuruda, A Dejda, RD Ryan, F Fournier, SY Chaney, ... Cell metabolism 33 (4), 818-832. e7, 2021 | 100 | 2021 |
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes S Kim, AR Davalos, SJ Heo, F Rodier, Y Zou, C Beausejour, P Kaminker, ... The Journal of cell biology 181 (3), 447-460, 2008 | 85 | 2008 |