The multiple faces of quercetin in neuroprotection B Ossola, TM Kääriäinen, PT Männistö Expert opinion on drug safety 8 (4), 397-409, 2009 | 202 | 2009 |
Amantadine protects dopamine neurons by a dual action: reducing activation of microglia and inducing expression of GNDF in astroglia B Ossola, N Schendzielorz, SH Chen, GS Bird, RK Tuominen, ... Neuropharmacology 61 (4), 574-582, 2011 | 117 | 2011 |
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin‐induced damage SH Chen, HM Wu, B Ossola, N Schendzielorz, BC Wilson, CH Chu, ... British journal of pharmacology 165 (2), 494-505, 2012 | 86 | 2012 |
Time-dependent protective and harmful effects of quercetin on 6-OHDA-induced toxicity in neuronal SH-SY5Y cells B Ossola, TM Kääriäinen, A Raasmaja, PT Männistö Toxicology 250 (1), 1-8, 2008 | 54 | 2008 |
Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures TM Kääriäinen, M Piltonen, B Ossola, H Kekki, Š Lehtonen, T Nenonen, ... Brain research 1203, 149-159, 2008 | 53 | 2008 |
The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice J Brelstaff, B Ossola, JJ Neher, T Klingstedt, KPR Nilsson, M Goedert, ... Frontiers in Neuroscience 9, 184, 2015 | 43 | 2015 |
The two pore potassium channel THIK‐1 regulates NLRP3 inflammasome activation S Drinkall, CB Lawrence, B Ossola, S Russell, C Bender, NB Brice, ... Glia 70 (7), 1301-1316, 2022 | 32 | 2022 |
Minocycline protects SH‐SY5Y cells from 6‐hydroxydopamine by inhibiting both caspase‐dependent and‐independent programmed cell death B Ossola, TA Lantto, KA Puttonen, RK Tuominen, A Raasmaja, ... Journal of neuroscience research 90 (3), 682-690, 2012 | 28 | 2012 |
Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation B Ossola, C Zhao, A Compston, S Pluchino, RJM Franklin, MG Spillantini Glia 64 (3), 457-471, 2016 | 26 | 2016 |
Characterisation of C101248: a novel selective THIK-1 channel inhibitor for the modulation of microglial NLRP3-inflammasome B Ossola, A Rifat, A Rowland, H Hunter, S Drinkall, C Bender, ... Neuropharmacology 224, 109330, 2023 | 17 | 2023 |
Differential contribution of THIK-1 K+ channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia A Rifat, B Ossola, RW Bürli, LA Dawson, NL Brice, A Rowland, M Lizio, ... Journal of neuroinflammation 21 (1), 58, 2024 | 5 | 2024 |
Paradoxical co-existence of protective and toxic effects of quercetin in the same in vitro neurodegeneration model B Ossola, TM K ri inen, A Raasmaja, PT M nnist european journal of pharmaceutical sciences 34 (1), S33-S33, 2008 | 4 | 2008 |
Discovery of CVN293, a Brain Permeable KCNK13 (THIK-1) Inhibitor Suitable for Clinical Assessment RW Bürli, KJ Doyle, L Dickson, A Rowland, K Matthews, AJ Stott, M Teall, ... ACS Medicinal Chemistry Letters 15 (5), 646-652, 2024 | 2 | 2024 |
Synthesis and SAR of novel GPR39 agonists and positive allosteric modulators R Burley, RC Hewer, M Teall, L Dickson, B Ossola, S Russell, C Bender, ... Bioorganic & Medicinal Chemistry Letters 61, 128607, 2022 | 2 | 2022 |
Putative neuroprotective compounds in in vitro models of dopaminergic neurodegeneration B Ossola Helsingin yliopisto, 2011 | 1 | 2011 |
THIK-1 controls microglial interleukin-1SS release in the human brain A Rifat, A Wilke, C Ugbode, B Ossola, K Doyle, MB Carlton, NL Brice, ... GLIA 71, E898-E898, 2023 | | 2023 |
3.221 AMANTADINE PROTECTS DOPAMINE NEURONS BY A DUAL ACTION: REDUCING ACTIVATION OF MICROGLIA AND INDUCING EXPRESSION OF GNDF IN ASTROGLIA B Ossola, N Schendzielorz, SH Chen, GS Bird, RK Tuominen, ... Parkinsonism and Related Disorders, S208-S209, 2012 | | 2012 |
P2. 107 The protective effect of minocycline in 6-OHDA-induced toxicity in neuronal SH-SY5Y cells B Ossola, T Lantto, A Raasmaja, P Männistö Parkinsonism and Related Disorders, S118, 2009 | | 2009 |
Suberoylanilide Hydroxamic Acid (SAHA), a Histone Deacetylase Inhibitor, Protects Dopaminergic Neurons from Neurotoxin-Induced Damage SH Chen, HM Wu, B Ossola, N Schendzielorz, BC Wilson, CH Chu, ... | | |