Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling YS Lee, JS Park, JH Kim, SM Jung, JY Lee, SJ Kim, SH Park Nature communications 2 (1), 460, 2011 | 140 | 2011 |
mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis C Martinez Calejman, S Trefely, SW Entwisle, A Luciano, SM Jung, ... Nature communications 11 (1), 575, 2020 | 123 | 2020 |
Brown adipose tissue development and metabolism SM Jung, J Sanchez-Gurmaches, DA Guertin Brown adipose tissue, 3-36, 2019 | 117 | 2019 |
A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1 JH Lee, SM Jung, KM Yang, E Bae, SG Ahn, JS Park, D Seo, M Kim, J Ha, ... Nature cell biology 19 (10), 1260-1273, 2017 | 113 | 2017 |
Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6 SM Jung, JH Lee, J Park, YS Oh, SK Lee, JS Park, YS Lee, JH Kim, ... Nature communications 4 (1), 2562, 2013 | 112 | 2013 |
Activin receptor‐like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes JH Yoon, SM Jung, SH Park, M Kato, T Yamashita, IK Lee, K Sudo, ... EMBO molecular medicine 5 (11), 1720-1739, 2013 | 80 | 2013 |
The complex roles of mechanistic target of rapamycin in adipocytes and beyond PL Lee, SM Jung, DA Guertin Trends in Endocrinology & Metabolism 28 (5), 319-339, 2017 | 71 | 2017 |
Non-canonical mTORC2 signaling regulates brown adipocyte lipid catabolism through SIRT6-FoxO1 SM Jung, CM Hung, SR Hildebrand, J Sanchez-Gurmaches, ... Molecular cell 75 (4), 807-822. e8, 2019 | 66 | 2019 |
The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation JH Kim, D Seo, SJ Kim, DW Choi, JS Park, J Ha, J Choi, JH Lee, SM Jung, ... EMBO reports 19 (4), e44378, 2018 | 54 | 2018 |
A reciprocal role of the Smad4-Taz axis in osteogenesis and adipogenesis of mesenchymal stem cells JS Park, M Kim, NJ Song, JH Kim, D Seo, JH Lee, SM Jung, JY Lee, J Lee, ... Stem Cells 37 (3), 368-381, 2019 | 50 | 2019 |
The deubiquitinating enzyme, ubiquitin‐specific peptidase 50, regulates inflammasome activation by targeting the ASC adaptor protein JY Lee, D Seo, J You, S Chung, JS Park, JH Lee, SM Jung, YS Lee, ... FEBS letters 591 (3), 479-490, 2017 | 46 | 2017 |
Brown fat organogenesis and maintenance requires AKT1 and AKT2 J Sanchez-Gurmaches, CM Calejman, SM Jung, H Li, DA Guertin Molecular Metabolism 23, 60-74, 2019 | 40 | 2019 |
The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway D Seo, SM Jung, JS Park, J Lee, J Ha, M Kim, SH Park EBioMedicine 49, 55-71, 2019 | 39 | 2019 |
In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate SM Jung, WG Doxsey, J Le, JA Haley, L Mazuecos, AK Luciano, H Li, ... Cell reports 36 (4), 2021 | 36 | 2021 |
Inhibition of lethal inflammatory responses through the targeting of membrane‐associated Toll‐like receptor 4 signaling complexes with a Smad6‐derived peptide YS Lee, JS Park, SM Jung, SD Kim, JH Kim, JY Lee, KC Jung, M Mamura, ... EMBO molecular medicine 7 (5), 577-592, 2015 | 32 | 2015 |
Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis G Park, JA Haley, J Le, SM Jung, TP Fitzgibbons, ED Korobkina, H Li, ... Nature metabolism 5 (7), 1204-1220, 2023 | 26 | 2023 |
Pellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9 JH Kim, KS Sung, SM Jung, YS Lee, JY Kwon, CY Choi, SH Park Molecules and cells 31, 85-89, 2011 | 18 | 2011 |
The lipid handling capacity of subcutaneous fat is programmed by mTORC2 during development WY Hsiao, SM Jung, Y Tang, JA Haley, R Li, H Li, CM Calejman, ... Cell reports 33 (1), 2020 | 15 | 2020 |
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1 AK Luciano, ED Korobkina, SP Lyons, JA Haley, SM Fluharty, SM Jung, ... Journal of Biological Chemistry 298 (10), 2022 | 11 | 2022 |
Stable isotope tracing and metabolomics to study in vivo brown adipose tissue metabolic fluxes SM Jung, J Le, WG Doxsey, JA Haley, G Park, DA Guertin, C Jang Brown Adipose Tissue: Methods and Protocols, 119-130, 2022 | 5 | 2022 |