关注
John Skidmore
John Skidmore
在 cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Autophagy and neurodegeneration: pathogenic mechanisms and therapeutic opportunities
FM Menzies, A Fleming, A Caricasole, CF Bento, SP Andrews, ...
Neuron 93 (5), 1015-1034, 2017
11442017
Small molecules, big targets: drug discovery faces the protein–protein interaction challenge
DE Scott, AR Bayly, C Abell, J Skidmore
Nature Reviews Drug Discovery 15 (8), 533-550, 2016
11092016
The different autophagy degradation pathways and neurodegeneration
A Fleming, M Bourdenx, M Fujimaki, C Karabiyik, GJ Krause, A Lopez, ...
Neuron 110 (6), 935-966, 2022
2802022
Asymmetric epoxidation of electron-deficient olefins
MJ Porter, J Skidmore
Chemical Communications, 1215-1225, 2000
2052000
Efficient asymmetric epoxidation of α, β-unsaturated ketones using a soluble triblock polyethylene glycol− polyamino acid catalyst
RW Flood, TP Geller, SA Petty, SM Roberts, J Skidmore, M Volk
Organic Letters 3 (5), 683-686, 2001
1182001
Polyamino acids as catalysts in asymmetric synthesis
MJ Porter, SM Roberts, J Skidmore
Bioorganic & medicinal chemistry 7 (10), 2145-2156, 1999
1011999
Total synthesis of (−)-nakadomarin A
AF Kyle, P Jakubec, DM Cockfield, E Cleator, J Skidmore, DJ Dixon
Chemical Communications 47 (36), 10037-10039, 2011
862011
Polyamino acid-catalysed asymmetric epoxidation: Sodium percarbonate as a source of base and oxidant
JV Allen, KH Drauz, RW Flood, SM Roberts, J Skidmore
Tetrahedron letters 40 (29), 5417-5420, 1999
771999
A detailed investigation of the aza-Prins reaction
AP Dobbs, SJJ Guesné, RJ Parker, J Skidmore, RA Stephenson, ...
Organic & Biomolecular Chemistry 8 (5), 1064-1080, 2010
752010
New procedures for the Juliß–Colonna asymmetric epoxidation: synthesis of (+)-clausenamide
MW Cappi, RW Flood, SM Roberts, NM Williamson, JA Smith
Chemical Communications, 1159-1160, 1998
711998
BACE-1 inhibitors part 3: identification of hydroxy ethylamines (HEAs) with nanomolar potency in cells
P Beswick, N Charrier, B Clarke, E Demont, C Dingwall, R Dunsdon, ...
Bioorganic & medicinal chemistry letters 18 (3), 1022-1026, 2008
692008
Systematic investigation of the permeability of androgen receptor PROTACs
DE Scott, TPC Rooney, ED Bayle, T Mirza, HMG Willems, JH Clarke, ...
ACS Medicinal Chemistry Letters 11 (8), 1539-1547, 2020
582020
Development of the Juliá− Colonna Asymmetric Epoxidation Reaction: Part 1. Preparation and Activation of the Polyleucine Catalyst
S Baars, KH Drauz, HP Krimmer, SM Roberts, J Sander, J Skidmore, ...
Organic process research & development 7 (4), 509-513, 2003
582003
3 α7 Nicotinic Acetylcholine Receptor Agonists and Positive Allosteric Modulators
AP Lightfoot, JNC Kew, J Skidmore
Progress in medicinal chemistry 46, 131-171, 2008
452008
A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
DE Scott, NJ Francis-Newton, ME Marsh, AG Coyne, G Fischer, ...
Cell chemical biology 28 (6), 835-847. e5, 2021
372021
Therapeutic inhibition of ferroptosis in neurodegenerative disease
SK Ryan, CL Ugalde, AS Rolland, J Skidmore, D Devos, TR Hammond
Trends in Pharmacological Sciences, 2023
362023
Rapid access to CF3-containing heterocycles
AP Dobbs, RJ Parker, J Skidmore
Tetrahedron Letters 49 (5), 827-831, 2008
362008
The effect of the primary structure of the polypeptide catalyst on the enantioselectivity of the Juliá–Colonna asymmetric epoxidation of enones
PA Bentley, RW Flood, SM Roberts, J Skidmore, CB Smith, JA Smith
Chemical Communications, 1616-1617, 2001
312001
β-Peptides as catalysts: poly-β-leucine as a catalyst for the Juliá–Colonna asymmetric epoxidation of enones
PE Coffey, KH Drauz, SM Roberts, J Skidmore, JA Smith
Chemical Communications, 2330-2331, 2001
302001
Biomimetic reactions in organic synthesis: Semi-pinacol rearrangements of some spirocyclic epoxyalcohols derived from Juliá-Colonna asymmetric epoxidations
B Hauer, JF Bickley, J Massue, PCA Pena, SM Roberts, J Skidmore
Canadian journal of chemistry 80 (6), 546-550, 2002
262002
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