A systematic analysis of the peripheral and CNS effects of systemic LPS, IL-1β, TNF-α and IL-6 challenges in C57BL/6 mice DT Skelly, E Hennessy, MA Dansereau, C Cunningham PloS one 8 (7), e69123, 2013 | 310 | 2013 |
Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research C Cunningham, E Hennessy Alzheimer's research & therapy 7, 1-13, 2015 | 217 | 2015 |
Astrocytes are primed by chronic neurodegeneration to produce exaggerated chemokine and cell infiltration responses to acute stimulation with the cytokines IL-1β and TNF-α E Hennessy, ÉW Griffin, C Cunningham Journal of Neuroscience 35 (22), 8411-8422, 2015 | 174 | 2015 |
Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for delirium DHJ Davis, DT Skelly, C Murray, E Hennessy, J Bowen, S Norton, ... The American journal of geriatric psychiatry 23 (4), 403-415, 2015 | 141 | 2015 |
Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunction AB Lopez‐Rodriguez, E Hennessy, CL Murray, A Nazmi, HJ Delaney, ... Alzheimer's & Dementia 17 (10), 1735-1755, 2021 | 127 | 2021 |
Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms DT Skelly, ÉW Griffin, CL Murray, S Harney, C O’Boyle, E Hennessy, ... Molecular psychiatry 24 (10), 1533-1548, 2019 | 121 | 2019 |
Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration E Hennessy, S Gormley, AB Lopez-Rodriguez, C Murray, C Murray, ... Brain, behavior, and immunity 59, 233-244, 2017 | 119 | 2017 |
Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression A Nazmi, RH Field, EW Griffin, O Haugh, E Hennessy, D Cox, R Reis, ... Glia 67 (7), 1254-1276, 2019 | 104 | 2019 |
Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer’s disease CL McDonald, E Hennessy, A Rubio-Araiz, B Keogh, W McCormack, ... Brain, behavior, and immunity 58, 191-200, 2016 | 94 | 2016 |
Repeated mild head injury leads to wide-ranging deficits in higher-order cognitive functions associated with the prefrontal cortex A Nolan, E Hennessy, K Krukowski, C Guglielmetti, MM Chaumeil, ... Journal of neurotrauma 35 (20), 2425-2434, 2018 | 52 | 2018 |
Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease Y Manso, PR Holland, A Kitamura, S Szymkowiak, J Duncombe, ... Glia 66 (1), 34-46, 2018 | 50 | 2018 |
Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age N McGarry, CL Murray, S Garvey, A Wilkinson, L Tortorelli, L Ryan, ... Brain, Behavior, and Immunity 95, 413-428, 2021 | 28 | 2021 |
Microglial and Astrocyte priming in the APP/PS1 model of Alzheimer’s Disease: increased vulnerability to acute inflammation and cognitive deficits AB Lopez-Rodriguez, E Hennessy, C Murray, A Lewis, N Barra, S Fagan, ... bioRxiv, 344218, 2018 | 13 | 2018 |
Double stranded RNA drives innate immune responses, sickness behavior and cognitive impairment dependent on dsRNA length, IFNAR1 expression and age. N McGarry, CL Murray, S Garvey, A Wilkinson, L Tortorelli, L Ryan, ... Biorxiv, 2021 | 9 | 2021 |
At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei R Reis, E Hennessy, C Murray, ÉW Griffin, C Cunningham Neuropathology and applied neurobiology 41 (6), 780-797, 2015 | 9 | 2015 |
Cholinergic signalling in the forebrain controls microglial phenotype and responses to systemic inflammation A Nazmi, EW Griffin, RH Field, S Doyle, E Hennessy, M O’Donnell, ... bioRxiv, 2021.01. 18.427123, 2021 | 6 | 2021 |
Correction: A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1β, TNF-α and IL-6 Challenges in C57BL/6 Mice DT Skelly, E Hennessy, MA Dansereau, C Cunningham Plos one 8 (12), 2013 | 3 | 2013 |
Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment KE Askew, J Beverley, E Sigfridsson, S Szymkowiak, K Emelianova, ... Glia 72 (2), 375-395, 2024 | 2 | 2024 |
Development and evaluation of a stroke research Public Patient Involvement Panel S O'Reilly, A Whiston, E Corbett, A O'Mahony, MX Manning, P Boland, ... HRB Open Research 7, 22, 2024 | | 2024 |
OptiCogs: feasibility of a multicomponent intervention to rehabilitate people with cognitive impairment post-stroke M O’Donoghue, P Boland, S Taylor, E Hennessy, E Murphy, S Leahy, ... Pilot and Feasibility Studies 9 (1), 178, 2023 | | 2023 |