Induction of the growth inhibitor IGF-binding protein 3 by p53 L Buckbinder, R Talbott, S Velasco-Miguel, I Takenaka, B Faha, ... Nature 377 (6550), 646-649, 1995 | 1217 | 1995 |
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ... Nature communications 11 (1), 163, 2020 | 574 | 2020 |
NF-κB RelA phosphorylation regulates RelA acetylation LF Chen, SA Williams, Y Mu, H Nakano, JM Duerr, L Buckbinder, ... Molecular and cellular biology 25 (18), 7966-7975, 2005 | 532 | 2005 |
PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes S Velasco-Miguel, L Buckbinder, P Jean, L Gelbert, R Talbott, J Laidlaw, ... Oncogene 18 (1), 127-137, 1999 | 298 | 1999 |
The initiator directs the assembly of a transcription factor IID-dependent transcription complex. J Carcamo, L Buckbinder, D Reinberg Proceedings of the National Academy of Sciences 88 (18), 8052-8056, 1991 | 246 | 1991 |
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis L Buckbinder, DT Crawford, H Qi, HZ Ke, LM Olson, KR Long, ... Proceedings of the National Academy of Sciences 104 (25), 10619-10624, 2007 | 178 | 2007 |
Structural characterization of proline-rich tyrosine kinase 2 (PYK2) reveals a unique (DFG-out) conformation and enables inhibitor design S Han, A Mistry, JS Chang, D Cunningham, M Griffor, PC Bonnette, ... Journal of Biological Chemistry 284 (19), 13193-13201, 2009 | 127 | 2009 |
The p53 tumor suppressor targets a novel regulator of G protein signaling L Buckbinder, S Velasco-Miguel, Y Chen, N Xu, R Talbott, L Gelbert, ... Proceedings of the National Academy of Sciences 94 (15), 7868-7872, 1997 | 127 | 1997 |
Thyroid hormone-induced gene expression changes in the developing frog limb. L Buckbinder, DD Brown Journal of Biological Chemistry 267 (36), 25786-25791, 1992 | 127 | 1992 |
Expression of the Xenopus laevis prolactin and thyrotropin genes during metamorphosis. L Buckbinder, DD Brown Proceedings of the National Academy of Sciences 90 (9), 3820-3824, 1993 | 123 | 1993 |
Identification of novel pheno-groups in heart failure with preserved ejection fraction using machine learning ÅK Hedman, C Hage, A Sharma, MJ Brosnan, L Buckbinder, LM Gan, ... Heart 106 (5), 342-349, 2020 | 114 | 2020 |
Myeloperoxidase inhibition improves ventricular function and remodeling after experimental myocardial infarction M Ali, B Pulli, G Courties, B Tricot, M Sebas, Y Iwamoto, I Hilgendorf, ... JACC: Basic to Translational Science 1 (7), 633-643, 2016 | 109 | 2016 |
Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes. L Buckbinder, R Talbott, BR Seizinger, N Kley Proceedings of the National Academy of Sciences 91 (22), 10640-10644, 1994 | 109 | 1994 |
Understanding the impact of the P-loop conformation on kinase selectivity CRW Guimarães, BK Rai, MJ Munchhof, S Liu, J Wang, SK Bhattacharya, ... Journal of chemical information and modeling 51 (6), 1199-1204, 2011 | 102 | 2011 |
Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis RJ Roth Flach, A Skoura, A Matevossian, LV Danai, W Zheng, C Cortes, ... Nature communications 6 (1), 8995, 2015 | 101 | 2015 |
PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti–glomerular basement membrane glomerulonephritis W Zheng, R Warner, R Ruggeri, C Su, C Cortes, A Skoura, J Ward, K Ahn, ... Journal of Pharmacology and Experimental Therapeutics 353 (2), 288-298, 2015 | 87 | 2015 |
Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity DP Walker, MP Zawistoski, MA McGlynn, JC Li, DW Kung, PC Bonnette, ... Bioorganic & medicinal chemistry letters 19 (12), 3253-3258, 2009 | 85 | 2009 |
Factors involved in specific transcription by mammalian RNA polymerase II: Role of factors IID and MLTF in transcription from the adenovirus major late and IVa2 promoters J Carcamo, S Lobos, A Merino, L Buckbinder, R Weinmann, V Natarajan, ... Journal of Biological Chemistry 264 (13), 7704-7714, 1989 | 84 | 1989 |
Phosphorylation of cellular proteins regulates their binding to the cAMP response element A Merino, L Buckbinder, FH Mermelstein, D Reinberg Journal of Biological Chemistry 264 (35), 21266-21276, 1989 | 82 | 1989 |
The glucocorticoid receptor: molecular mechanism and new therapeutic opportunities L Buckbinder, RP Robinson Current Drug Targets-Inflammation & Allergy 1 (2), 127-136, 2002 | 78 | 2002 |