Cell-penetrating peptides: Emerging tools for mRNA delivery H Yokoo, M Oba, S Uchida Pharmaceutics 14 (1), 78, 2021 | 60 | 2021 |
Development of antimicrobial stapled peptides based on magainin 2 sequence M Hirano, C Saito, H Yokoo, C Goto, R Kawano, T Misawa, Y Demizu Molecules 26 (2), 444, 2021 | 36 | 2021 |
Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids H Yokoo, M Hirano, T Misawa, Y Demizu ChemMedChem 16 (8), 1226-1233, 2021 | 35 | 2021 |
Temperature-dependent formation of N-nitrosodimethylamine during the storage of ranitidine reagent powders and tablets Y Abe, E Yamamoto, H Yoshida, A Usui, N Tomita, H Kanno, S Masada, ... Chemical and Pharmaceutical Bulletin 68 (10), 1008-1012, 2020 | 32 | 2020 |
Development of a hematopoietic prostaglandin D synthase-degradation inducer H Yokoo, N Shibata, M Naganuma, Y Murakami, K Fujii, T Ito, K Aritake, ... ACS Medicinal Chemistry Letters 12 (2), 236-241, 2021 | 26 | 2021 |
Discovery of a highly potent and selective degrader targeting hematopoietic prostaglandin D synthase via in silico design H Yokoo, N Shibata, A Endo, T Ito, Y Yanase, Y Murakami, K Fujii, ... Journal of Medicinal Chemistry 64 (21), 15868-15882, 2021 | 25 | 2021 |
Fcγ receptor-dependent internalization and off-target cytotoxicity of antibody-drug conjugate aggregates M Aoyama, M Tada, H Yokoo, Y Demizu, A Ishii-Watabe Pharmaceutical research 39 (1), 89-103, 2022 | 22 | 2022 |
Rational Design of Helix‐Stabilized Antimicrobial Peptide Foldamers Containing α, α‐Disubstituted Amino Acids or Side‐Chain Stapling M Hirano, C Saito, C Goto, H Yokoo, R Kawano, T Misawa, Y Demizu ChemPlusChem 85 (12), 2731-2736, 2020 | 20 | 2020 |
De novo design of cell‐penetrating foldamers H Yokoo, T Misawa, Y Demizu The Chemical Record 20 (9), 912-921, 2020 | 18 | 2020 |
N-Nitrosodimethylamine (NDMA) formation from ranitidine impurities: possible root causes of the presence of NDMA in ranitidine hydrochloride H Yokoo, E Yamamoto, S Masada, N Uchiyama, G Tsuji, T Hakamatsuka, ... Chemical and Pharmaceutical Bulletin 69 (9), 872-876, 2021 | 16 | 2021 |
Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors H Yokoo, N Ohoka, M Naito, Y Demizu Bioorganic & Medicinal Chemistry 28 (15), 115595, 2020 | 15 | 2020 |
Structural development of canthin-5, 6-dione moiety as a fluorescent dye and its application to novel fluorescent sensors H Yokoo, A Ohsaki, H Kagechika, T Hirano Tetrahedron 72 (39), 5872-5879, 2016 | 15 | 2016 |
Peptide stapling improves the sustainability of a peptide-based chimeric molecule that induces targeted protein degradation H Yokoo, N Ohoka, M Takyo, T Ito, K Tsuchiya, T Kurohara, K Fukuhara, ... International Journal of Molecular Sciences 22 (16), 8772, 2021 | 14 | 2021 |
Development of agonist-based PROTACs targeting liver X receptor H Xu, N Ohoka, H Yokoo, K Nemoto, T Ohtsuki, H Matsufuji, M Naito, ... Frontiers in chemistry 9, 674967, 2021 | 13 | 2021 |
Development of Rapid and Facile Solid‐Phase Synthesis of PROTACs via a Variety of Binding Styles H Xu, T Kurohara, R Takano, H Yokoo, N Shibata, N Ohoka, T Inoue, ... ChemistryOpen 11 (7), e202200131, 2022 | 11 | 2022 |
Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine H Yokoo, M Hirano, N Ohoka, T Misawa, Y Demizu Journal of Peptide Science 27 (12), e3360, 2021 | 11 | 2021 |
Synthesis of (S)-(−)-Cucurbitine and Conformation of Its Homopeptides Y Yamaberi, R Eto, T Umeno, T Kato, M Doi, H Yokoo, M Oba, M Tanaka Organic Letters 23 (11), 4358-4362, 2021 | 9 | 2021 |
Unique Properties of 1,5‐Naphthyridin‐2(1H)‐one Derivatives as Environment‐Polarity‐Sensitive Fluorescent Dyes H Yokoo, A Ohsaki, H Kagechika, T Hirano European Journal of Organic Chemistry 2018 (5), 679-687, 2018 | 9 | 2018 |
Development of Photoswitchable Estrogen Receptor Ligands K Tsuchiya, T Umeno, G Tsuji, H Yokoo, M Tanaka, K Fukuhara, ... Chemical and Pharmaceutical Bulletin 68 (4), 398-402, 2020 | 8 | 2020 |
Recent advances in PROTAC technology toward new therapeutic modalities H Yokoo, M Naganuma, M Oba, Y Demizu Chemistry & Biodiversity 19 (11), e202200828, 2022 | 7 | 2022 |