Fast reconstruction of compact context-specific metabolic network models N Vlassis, MP Pacheco, T Sauter PLoS computational biology 10 (1), e1003424, 2014 | 259 | 2014 |
The gut microbial metabolite formate exacerbates colorectal cancer progression D Ternes, M Tsenkova, VI Pozdeev, M Meyers, E Koncina, S Atatri, ... Nature metabolism 4 (4), 458-475, 2022 | 132 | 2022 |
Integrated in vitro and in silico modeling delineates the molecular effects of a synbiotic regimen on colorectal-cancer-derived cells G Kacy, RG Javier, H Almut, U Pit, B Tamara, P Maria Pires, J Baginska, ... Cell reports, 2019 | 76* | 2019 |
Identifying and targeting cancer-specific metabolism with network-based drug target prediction MP Pacheco, T Bintener, D Ternes, D Kulms, S Haan, E Letellier, T Sauter EBioMedicine 43, 98-106, 2019 | 67 | 2019 |
Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network MP Pacheco, E John, T Kaoma, M Heinäniemi, N Nicot, L Vallar, JL Bueb, ... BMC genomics 16 (1), 809, 2015 | 50 | 2015 |
Loss of Ambra1 promotes melanoma growth and invasion L Di Leo, V Bodemeyer, FM Bosisio, G Claps, M Carretta, S Rizza, ... Nature communications 12 (1), 2550, 2021 | 42 | 2021 |
Benchmarking procedures for high-throughput context specific reconstruction algorithms M Pires Pacheco, T Pfau, T Sauter Frontiers in Physiology 6, 410, 2016 | 36 | 2016 |
The power of LC-MS based multiomics: exploring adipogenic differentiation of human mesenchymal stem/stromal cells E Rampler, D Egger, H Schoeny, M Rusz, MP Pacheco, G Marino, ... Molecules 24 (19), 3615, 2019 | 28 | 2019 |
The neural stem cell fate determinant TRIM32 regulates complex behavioral traits AL Hillje, E Beckmann, MAS Pavlou, C Jaeger, MP Pacheco, T Sauter, ... Frontiers in Cellular Neuroscience 9, 75, 2015 | 24 | 2015 |
Towards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond T Pfau, MP Pacheco, T Sauter Briefings in Bioinformatics 17 (6), 1060-1069, 2016 | 22 | 2016 |
DCcov: Repositioning of drugs and drug combinations for SARS-CoV-2 infected lung through constraint-based modeling A Kishk, MP Pacheco, T Sauter Iscience 24 (11), 2021 | 16 | 2021 |
Towards the routine use of in silico screenings for drug discovery using metabolic modelling T Bintener, MP Pacheco, T Sauter Biochemical Society Transactions 48 (3), 955-969, 2020 | 16 | 2020 |
A dynamic multi-tissue model to study human metabolism P Martins Conde, T Pfau, M Pires Pacheco, T Sauter NPJ systems biology and applications 7 (1), 5, 2021 | 13 | 2021 |
The FASTCORE family: For the fast reconstruction of compact context-specific metabolic networks models MP Pacheco, T Sauter Metabolic Network Reconstruction and Modeling: Methods and Protocols, 101-110, 2018 | 13 | 2018 |
Importance of the biomass formulation for cancer metabolic modeling and drug prediction MM García, M Pacheco, T Bintener, L Presta, T Sauter Iscience 24 (10), 2021 | 11 | 2021 |
Towards the network-based prediction of repurposed drugs using patient-specific metabolic models MP Pacheco, T Bintener, T Sauter EBioMedicine 43, 26-27, 2019 | 8 | 2019 |
Project-based learning course on metabolic network modelling in computational systems biology T Sauter, T Bintener, A Kishk, L Presta, T Prohaska, D Guignard, N Zeng, ... PLoS computational biology 18 (1), e1009711, 2022 | 7 | 2022 |
Bruceine D identified as a drug candidate against breast cancer by a novel drug selection pipeline and cell viability assay C Cipriani, MP Pacheco, A Kishk, M Wachich, D Abankwa, ... Pharmaceuticals 15 (2), 179, 2022 | 5 | 2022 |
Review of current human genome-scale metabolic models for brain cancer and neurodegenerative diseases A Kishk, MP Pacheco, T Heurtaux, L Sinkkonen, J Pang, S Fritah, ... Cells 11 (16), 2486, 2022 | 4 | 2022 |
Fast reconstruction of compact context-specific metabolic networks via integration of microarray data MP Pacheco, T Sauter arXiv preprint arXiv:1407.6534, 2014 | 3 | 2014 |