Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies B Greco, V Malacarne, F De Girardi, GM Scotti, F Manfredi, E Angelino, ... Science translational medicine 14 (628), eabg3072, 2022 | 73 | 2022 |
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 E Ruffo, V Malacarne, SE Larsen, R Das, L Patrussi, C Wülfing, C Biskup, ... Science translational medicine 8 (321), 321ra7-321ra7, 2016 | 48 | 2016 |
B7h triggering inhibits the migration of tumor cell lines C Dianzani, R Minelli, CL Gigliotti, S Occhipinti, M Giovarelli, L Conti, ... The Journal of Immunology 192 (10), 4921-4931, 2014 | 48 | 2014 |
The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness E Rainero, C Cianflone, PE Porporato, F Chianale, V Malacarne, V Bettio, ... Plos one 9 (6), e97144, 2014 | 41 | 2014 |
Diacylglycerol kinases: shaping diacylglycerol and phosphatidic acid gradients to control cell polarity G Baldanzi, V Bettio, V Malacarne, A Graziani Frontiers in cell and developmental biology 4, 140, 2016 | 34 | 2016 |
Unacylated ghrelin enhances satellite cell function and relieves the dystrophic phenotype in duchenne muscular dystrophy mdx model S Reano, E Angelino, M Ferrara, V Malacarne, H Sustova, O Sabry, ... Stem Cells 35 (7), 1733-1746, 2017 | 25 | 2017 |
Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction S Velnati, S Centonze, G Rossino, B Purghè, A Antona, L Racca, S Mula, ... Frontiers in Immunology 14, 1043603, 2023 | 3 | 2023 |
Combining De-Glycosylating Agents with CAR-T Cells for Targeting Solid Tumors and Reducing Toxicity B Greco, K Paolella, B Camisa, V Malacarne, L Falcone, A Graziani, ... Blood 132, 4544, 2018 | 2 | 2018 |
Mouse satellite cell isolation and transplantation E Angelino, S Reano, M Ferrara, E Agosti, H Sustova, V Malacarne, ... Bio-protocol 8 (2), e2696-e2696, 2018 | 2 | 2018 |
OVERCOMING TUMOR RESISTANCE INDUCED BY N-GLYCOSYLATION BOOSTS CAR T CELL EFFICACY AGAINST SOLID MALIGNANCIES B Greco, V Malacarne, C Sirini, GM Scotti, B Camisa, L Falcone, ... HAEMATOLOGICA 105, S18-S18, 2020 | | 2020 |
Combining De-Glycosylating Agents with CAR T Cells for Targeting Solid Tumors and Improving Therapeutic Index B Greco, V Malacarne, C Sirini, B Camisa, K Paolella, L Falcone, ... MOLECULAR THERAPY 28 (4), 33-33, 2020 | | 2020 |
Hampering Tumor Glycosylation Improves the Therapeutic Index of CAR-T Cells Against Solid Malignancies B Greco, K Paolella, V Malacarne, B Camisa, A Graziani, C Bonini, ... MOLECULAR THERAPY 27 (4), 432-432, 2019 | | 2019 |
Sviluppo di inibitori di DGKα per la terapia della psoriasi all'interno del progetto" Terapie innovative per la psoriasi (TIPSO)" V Bettio, S Velnati, V Malacarne, A Massarotti, A Graziani, GC Tron, ... ., 2016 | | 2016 |
INHIBITION OF DIACYLGLYCEROL KINASE ALPHA RESTORES SENSITIVITY TO TCR-INDUCED CELL DEATH AND LESSENS IMMUNOPATHOLOGY IN A MURINE MODEL OF XLP-ASSOCIATED HEMOPHAGOCYTIC … KE Nichols, E Ruffo, V Malacarne, S Larsen, R Das, L Patrussi, ... PEDIATRIC BLOOD & CANCER 62, S134-S134, 2015 | | 2015 |
Inhibition of Diacylglycerol kinase alpha restores TCR-induced diacylglycerol signaling and restimulation-induced cell death in XLP1 T lymphocytes V Malacarne Università degli Studi del Piemonte Orientale Amedeo Avogadro, 2015 | | 2015 |
Sintesi e caratterizzazione di nuovi inibitori di DGKα V Malacarne, E Ruffo, A Massarotti, G Baldanzi, GC Tron, A Graziani ., 2014 | | 2014 |
Diacylglycerol kinase alpha produced phosphatidic acid controls myosin light chain kinase localization and activity in HGF stimulated epithelial cells. L Birolo, P Malacarne, C Pagnozzi, S Filigheddu, P Pucci THE FEBS JOURNAL 278, 381-381, 2011 | | 2011 |
Inhibition of diacylglycerol kinase a restores restimulation-induced cell death and reduces immunopathology in XLP-1 E Ruffo, V Malacarne, SE Larsen, R Das, L Patrussi, C Wülfing, C Biskup, ... | | |
SAP-mediated inhibition of Diacylglycerol kinase alpha regulates TCR-induced diacylglycerol signaling and restimulation induced cell death in XLP patients V Malacarne, G Baldanzi, A Graziani, E Ruffo, A Snow, CT Baldari, ... | | |