Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate AA Chakraborty, T Laukka, M Myllykoski, AE Ringel, MA Booker, ... Science 363 (6432), 1217-1222, 2019 | 356 | 2019 |
Antagonistic functions of MBP and CNP establish cytosolic channels in CNS myelin N Snaidero, C Velte, M Myllykoski, A Raasakka, A Ignatev, HB Werner, ... Cell reports 18 (2), 314-323, 2017 | 194 | 2017 |
Myelin‐specific proteins: A structurally diverse group of membrane‐interacting molecules H Han, M Myllykoski, S Ruskamo, C Wang, P Kursula Biofactors 39 (3), 233-241, 2013 | 94 | 2013 |
Membrane association landscape of myelin basic protein portrays formation of the myelin major dense line A Raasakka, S Ruskamo, J Kowal, R Barker, A Baumann, A Martel, ... Scientific reports 7 (1), 4974, 2017 | 77 | 2017 |
Molecular structure and function of myelin protein P0 in membrane stacking A Raasakka, S Ruskamo, J Kowal, H Han, A Baumann, M Myllykoski, ... Scientific reports 9 (1), 1-15, 2019 | 54 | 2019 |
Charge isomers of myelin basic protein: structure and interactions with membranes, nucleotide analogues, and calmodulin C Wang, U Neugebauer, J Bürck, M Myllykoski, P Baumgärtel, J Popp, ... PLoS One 6 (5), e19915, 2011 | 53 | 2011 |
Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule V Majava, C Wang, M Myllykoski, SM Kangas, SU Kang, N Hayashi, ... Amino acids 39 (1), 59-71, 2010 | 49 | 2010 |
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases T Laukka, M Myllykoski, RE Looper, P Koivunen Journal of molecular biology 430 (18), 3081-3092, 2018 | 44 | 2018 |
Myelin 2′, 3′-cyclic nucleotide 3′-phosphodiesterase: active-site ligand binding and molecular conformation M Myllykoski, A Raasakka, H Han, P Kursula PloS one 7 (2), e32336, 2012 | 44 | 2012 |
Structural and functional evolution of 2′, 3′-cyclic nucleotide 3′-phosphodiesterase M Myllykoski, L Seidel, G Muruganandam, A Raasakka, AE Torda, ... Brain research 1641, 64-78, 2016 | 39 | 2016 |
High‐affinity heterotetramer formation between the large myelin‐associated glycoprotein and the dynein light chain DYNLL 1 M Myllykoski, MA Eichel, RB Jung, S Kelm, HB Werner, P Kursula Journal of neurochemistry 147 (6), 764-783, 2018 | 26 | 2018 |
Determinants of ligand binding and catalytic activity in the myelin enzyme 2′, 3′-cyclic nucleotide 3′-phosphodiesterase A Raasakka, M Myllykoski, S Laulumaa, M Lehtimäki, M Härtlein, ... Scientific Reports 5 (1), 16520, 2015 | 26 | 2015 |
The N‐terminal domain of the myelin enzyme 2′, 3′‐cyclic nucleotide 3′‐phosphodiesterase: direct molecular interaction with the calcium sensor calmodulin M Myllykoski, K Itoh, SM Kangas, AM Heape, SU Kang, G Lubec, I Kursula, ... Journal of neurochemistry 123 (4), 515-524, 2012 | 26 | 2012 |
Biallelic loss-of-function P4HTM gene variants cause hypotonia, hypoventilation, intellectual disability, dysautonomia, epilepsy, and eye abnormalities (HIDEA syndrome) E Rahikkala, M Myllykoski, R Hinttala, P Vieira, N Nayebzadeh, S Weiss, ... Genetics in Medicine 21 (10), 2355-2363, 2019 | 25 | 2019 |
Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility M Myllykoski, A Baumann, K Hensley, P Kursula Amino Acids 49 (4), 747-759, 2017 | 24 | 2017 |
Expression, purification, and initial characterization of different domains of recombinant mouse 2', 3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the … M Myllykoski, P Kursula BMC research notes 3 (1), 1-7, 2010 | 22 | 2010 |
Structural basis for PDZ domain interactions in the post‐synaptic density scaffolding protein Shank3 SK Ponna, S Ruskamo, M Myllykoski, C Keller, TM Boeckers, P Kursula Journal of neurochemistry 145 (6), 449-463, 2018 | 20 | 2018 |
Complex formation between calmodulin and a peptide from the intracellular loop of the gap junction protein connexin43: Molecular conformation and energetics of binding M Myllykoski, K Kuczera, P Kursula Biophysical chemistry 144 (3), 130-135, 2009 | 20 | 2009 |
Crystallographic analysis of the reaction cycle of 2′, 3′-cyclic nucleotide 3′-phosphodiesterase, a unique member of the 2H phosphoesterase family M Myllykoski, A Raasakka, M Lehtimäki, H Han, I Kursula, P Kursula Journal of molecular biology 425 (22), 4307-4322, 2013 | 19 | 2013 |
Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution SK Ponna, M Myllykoski, TM Boeckers, P Kursula Biochemical and biophysical research communications 490 (3), 806-812, 2017 | 18 | 2017 |