Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand L Côrte-Real, B Karas, P Gírio, A Moreno, F Avecilla, F Marques, ... European journal of medicinal chemistry 163, 853-863, 2019 | 48 | 2019 |
5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells S Ranjbar, R Khonkarn, A Moreno, H Baubichon-Cortay, R Miri, ... Toxicology and Applied Pharmacology 362, 136-149, 2019 | 40 | 2019 |
Methyl-cyclopentadienyl ruthenium compounds with 2, 2′-bipyridine derivatives display strong anticancer activity and multidrug resistance potential L Côrte-Real, RG Teixeira, P Gírio, E Comsa, A Moreno, R Nasr, ... Inorganic Chemistry 57 (8), 4629-4639, 2018 | 40 | 2018 |
Monoterpene indole alkaloid azine derivatives as MDR reversal agents A Paterna, R Khonkarn, S Mulhovo, A Moreno, PM Girio, ... Bioorganic & medicinal chemistry 26 (2), 421-434, 2018 | 33 | 2018 |
Optimizing the flavanone core toward new selective nitrogen-containing modulators of ABC transporters RJ Ferreira, R Baptista, A Moreno, PG Madeira, R Khonkarn, ... Future Medicinal Chemistry 10 (7), 725-741, 2018 | 29 | 2018 |
PDR-like ABC systems in pathogenic fungi A Moreno, A Banerjee, R Prasad, P Falson Research in microbiology 170 (8), 417-425, 2019 | 28 | 2019 |
Atomic modelling and systematic mutagenesis identify residues in multiple drug binding sites that are essential for drug resistance in the major Candida transporter Cdr1 S Nim, LG Lobato, A Moreno, V Chaptal, MK Rawal, P Falson, R Prasad Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (11), 2858-2870, 2016 | 22 | 2016 |
Molecular basis of substrate polyspecificity of the Candida albicans Mdr1p multidrug/H+ antiporter AK Redhu, A Banerjee, AH Shah, A Moreno, MK Rawal, R Nair, P Falson, ... Journal of molecular biology 430 (5), 682-694, 2018 | 21 | 2018 |
Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties P Gilson, F Josa-Prado, C Beauvineau, D Naud-Martin, ... Scientific reports 7 (1), 10209, 2017 | 21 | 2017 |
Chromones bearing amino acid residues: Easily accessible and potent inhibitors of the breast cancer resistance protein ABCG2 E Roussel, A Moréno, N Altounian, C Philouze, B Pérès, A Thomas, ... European Journal of Medicinal Chemistry 202, 112503, 2020 | 18 | 2020 |
W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans A Banerjee, AH Shah, AK Redhu, A Moreno, P Falson, R Prasad Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (5), 965-972, 2018 | 16 | 2018 |
Cdr1p highlights the role of the non-hydrolytic ATP-binding site in driving drug translocation in asymmetric ABC pumps A Banerjee, A Moreno, MF Khan, R Nair, S Sharma, S Sen, AK Mondal, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (2), 183131, 2020 | 15 | 2020 |
ABCG: a new fold of ABC exporters and a whole new bag of riddles! A Banerjee, A Moreno, J Pata, P Falson, R Prasad Advances in Protein Chemistry and Structural Biology 123, 163-191, 2021 | 14 | 2021 |
Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2 N Guragossian, B Belhani, A Moreno, MT Nunes, L Gonzalez-Lobato, ... European Journal of Medicinal Chemistry 211, 113017, 2021 | 13 | 2021 |
pHluorin enables insights into the transport mechanism of antiporter Mdr1: R215 is critical for drug/H+ antiport AK Redhu, NK Khandelwal, A Banerjee, A Moreno, P Falson, R Prasad Biochemical Journal 473 (19), 3127-3145, 2016 | 10 | 2016 |
Purification and characterization of Cdr1, the drug-efflux pump conferring azole resistance in Candida species J Pata, A Moreno, B Wiseman, S Magnard, I Lehlali, M Dujardin, ... Biochimie 220, 167-178, 2024 | 3 | 2024 |
Synthesis of well‐defined methacrylate copolymers and their use for stabilizing membrane proteins V Monjal, A Moreno, D Glueck, S Keller, P Guillet, G Durand Journal of Polymer Science 61 (24), 3307-3317, 2023 | 1 | 2023 |
Non-ionic cholesterol-based additives for the stabilization of membrane proteins D Cornut, M Soulié, A Moreno, GNM Boussambe, M Damian, S Igonet, ... Biochimie 205, 27-39, 2023 | 1 | 2023 |
Selective bcrp/abcg2 transporter inhibitors as agents to abolish resistance to anti-cancer agents A Boumendjel, P Falson, A Moreno, B Peres, E Roussel US Patent App. 17/629,966, 2022 | | 2022 |
Production and Purification of a GFP-Tagged ABC Transporter CaCdr1p J Pata, A Moreno, S Magnard, A Banerjee, R Prasad, P Falson Heterologous Expression of Membrane Proteins: Methods and Protocols, 175-185, 2022 | | 2022 |