Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex A Scior, A Buntru, K Arnsburg, A Ast, M Iburg, K Juenemann, ML Pigazzini, ... The EMBO journal 37 (2), 282-299, 2018 | 128 | 2018 |
Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains C Haenig, N Atias, AK Taylor, A Mazza, MH Schaefer, J Russ, ... Cell reports 32 (7), 2020 | 78 | 2020 |
PolyQ tract toxicity in SCA1 is length dependent in the absence of CAG repeat interruption S Nethisinghe, ML Pigazzini, S Pemble, MG Sweeney, R Labrum, ... Frontiers in cellular neuroscience 12, 200, 2018 | 21 | 2018 |
An expanded polyproline domain maintains mutant huntingtin soluble in vivo and during aging ML Pigazzini, M Lawrenz, A Margineanu, GS Kaminski Schierle, J Kirstein Frontiers in Molecular Neuroscience 14, 721749, 2021 | 11 | 2021 |
Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT SM Ayala Mariscal, ML Pigazzini, Y Richter, M Özel, IL Grothaus, J Protze, ... Nature Communications 13 (1), 4692, 2022 | 10 | 2022 |
Characterization of amyloid structures in aging C. elegans using fluorescence lifetime imaging ML Pigazzini, C Gallrein, M Iburg, GK Schierle, J Kirstein JoVE (Journal of Visualized Experiments), e61004, 2020 | 8 | 2020 |
In vivo quantification of protein turnover in aging C. Elegans using photoconvertible Dendra2 ML Pigazzini, J Kirstein JoVE (Journal of Visualized Experiments), e61196, 2020 | 7 | 2020 |
Complementary methodologies and diverse model systems provide translational insight into the aggregation properties of neurodegenerative diseases ML Pigazzini | | 2022 |
PP55. ONCOGENIC MICRORNAS REVEAL NOVEL NEURAL TUMOR MODEL MC Pirillo, ML Pigazzini, ME Cohen, R Sousa-Nunes Neuro-Oncology 19 (Suppl 1), i15, 2017 | | 2017 |