| In silico methods to address polypharmacology: current status, applications and future perspectives A Lavecchia, C Cerchia Drug Discovery Today 21 (2), 288-298, 2016 | 214 | 2016 |
| Targeting SARS-CoV-2 proteases and polymerase for COVID-19 treatment: state of the art and future opportunities R Cannalire, C Cerchia, AR Beccari, FS Di Leva, V Summa Journal of medicinal chemistry 65 (4), 2716-2746, 2020 | 183 | 2020 |
| Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode D Capelli, C Cerchia, R Montanari, F Loiodice, P Tortorella, A Laghezza, ... Scientific reports 6 (1), 34792, 2016 | 84 | 2016 |
| SARS-CoV-2 entry inhibitors: small molecules and peptides targeting virus or host cells R Cannalire, I Stefanelli, C Cerchia, AR Beccari, S Pelliccia, V Summa International Journal of Molecular Sciences 21 (16), 5707, 2020 | 79 | 2020 |
| Computational studies of SARS-CoV-2 3CLpro: Insights from MD simulations A Grottesi, N Bešker, A Emerson, C Manelfi, AR Beccari, F Frigerio, ... International journal of molecular sciences 21 (15), 5346, 2020 | 66 | 2020 |
| New avenues in artificial-intelligence-assisted drug discovery C Cerchia, A Lavecchia Drug Discovery Today 28 (4), 103516, 2023 | 49 | 2023 |
| Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages F De Falco, C Di Giovanni, C Cerchia, D De Stefano, A Capuozzo, C Irace, ... Biochemical pharmacology 104, 83-94, 2016 | 37 | 2016 |
| Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays A Lavecchia, C Di Giovanni, C Cerchia, A Russo, G Russo, E Novellino Journal of medicinal chemistry 56 (7), 2861-2873, 2013 | 34 | 2013 |
| Identification of the first PPARα/γ dual agonist able to bind to canonical and alternative sites of PPARγ and to inhibit its Cdk5-mediated phosphorylation A Laghezza, L Piemontese, C Cerchia, R Montanari, D Capelli, M Giudici, ... Journal of Medicinal Chemistry 61 (18), 8282-8298, 2018 | 29 | 2018 |
| New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity L Piemontese, C Cerchia, A Laghezza, P Ziccardi, S Sblano, P Tortorella, ... European journal of medicinal chemistry 127, 379-397, 2017 | 28 | 2017 |
| Identification of a new series of amides as non-covalent proteasome inhibitors K Scarbaci, V Troiano, N Micale, R Ettari, L Tamborini, C Di Giovanni, ... European Journal of Medicinal Chemistry 76, 1-9, 2014 | 28 | 2014 |
| Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors V Troiano, K Scarbaci, R Ettari, N Micale, C Cerchia, A Pinto, ... European Journal of Medicinal Chemistry 83, 1-14, 2014 | 27 | 2014 |
| The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands D Zurlo, P Ziccardi, C Votino, T Colangelo, C Cerchia, F Dal Piaz, ... Biochemical pharmacology 108, 22-35, 2016 | 26 | 2016 |
| Novel phenyldiazenyl fibrate analogues as PPAR α/γ/δ pan-agonists for the amelioration of metabolic syndrome L Giampietro, A Laghezza, C Cerchia, R Florio, L Recinella, F Capone, ... ACS Medicinal Chemistry Letters 10 (4), 545-551, 2019 | 25 | 2019 |
| Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature A Lavecchia, C Di Giovanni, C Cerchia Expert opinion on therapeutic patents 24 (4), 383-400, 2014 | 25 | 2014 |
| Small molecule drugs and targeted therapy for melanoma: current strategies and future directions C Cerchia, A Lavecchia Current medicinal chemistry 24 (21), 2312-2344, 2017 | 24 | 2017 |
| Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells A Capasso, C Cerchia, C Di Giovanni, G Granato, F Albano, S Romano, ... Oncotarget 6 (37), 40202, 2015 | 22 | 2015 |
| Development of novel amides as noncovalent inhibitors of immunoproteasomes R Ettari, C Cerchia, S Maiorana, M Guccione, E Novellino, A Bitto, ... ChemMedChem 14 (8), 842-852, 2019 | 21 | 2019 |
| Recent advances in developing PCSK9 inhibitors for lipid-lowering therapy A Lavecchia, C Cerchia Future medicinal chemistry 11 (5), 423-441, 2019 | 21 | 2019 |
| Discovery of novel naphthylphenylketone and naphthylphenylamine derivatives as cell division cycle 25B (CDC25B) phosphatase inhibitors: design, synthesis, inhibition mechanism … C Cerchia, R Nasso, M Mori, S Villa, A Gelain, A Capasso, F Aliotta, ... Journal of Medicinal Chemistry 62 (15), 7089-7110, 2019 | 19 | 2019 |
