Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and-independent pathways JD Rotty, C Wu, EM Haynes, C Suarez, JD Winkelman, HE Johnson, ... Developmental cell 32 (1), 54-67, 2015 | 276 | 2015 |
The spatiotemporal limits of developmental Erk signaling HE Johnson, Y Goyal, NL Pannucci, T Schüpbach, SY Shvartsman, ... Developmental cell 40 (2), 185-192, 2017 | 191 | 2017 |
Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism ES Welf, S Ahmed, HE Johnson, AT Melvin, JM Haugh Journal of Cell Biology 197 (1), 105-114, 2012 | 125 | 2012 |
Signaling dynamics control cell fate in the early Drosophila embryo HE Johnson, JE Toettcher Developmental cell 48 (3), 361-370. e3, 2019 | 119 | 2019 |
F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling HE Johnson, SJ King, SB Asokan, JD Rotty, JE Bear, JM Haugh Journal of Cell Biology 208 (4), 443-455, 2015 | 117 | 2015 |
Mesenchymal chemotaxis requires selective inactivation of myosin II at the leading edge via a noncanonical PLCγ/PKCα pathway SB Asokan, HE Johnson, A Rahman, SJ King, JD Rotty, IP Lebedeva, ... Developmental cell 31 (6), 747-760, 2014 | 84 | 2014 |
Lamellipodia are crucial for haptotactic sensing and response SJ King, SB Asokan, EM Haynes, SP Zimmerman, JD Rotty, JG Alb Jr, ... Journal of cell science 129 (12), 2329-2342, 2016 | 82 | 2016 |
Illuminating developmental biology with cellular optogenetics HE Johnson, JE Toettcher Current opinion in biotechnology 52, 42-48, 2018 | 78 | 2018 |
Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection BY Winer, E Shirvani-Dastgerdi, Y Bram, J Sellau, BE Low, H Johnson, ... Science translational medicine 10 (447), eaap9328, 2018 | 40 | 2018 |
GMFβ controls branched actin content and lamellipodial retraction in fibroblasts EM Haynes, SB Asokan, SJ King, HE Johnson, JM Haugh, JE Bear Journal of Cell Biology 209 (6), 803-812, 2015 | 39 | 2015 |
Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility ES Welf, HE Johnson, JM Haugh Molecular biology of the cell 24 (24), 3945-3955, 2013 | 35 | 2013 |
Optogenetic rescue of a patterning mutant HE Johnson, NJV Djabrayan, SY Shvartsman, JE Toettcher Current Biology 30 (17), 3414-3424. e3, 2020 | 33 | 2020 |
Preformation and epigenesis converge to specify primordial germ cell fate in the early Drosophila embryo MM Colonnetta, Y Goyal, HE Johnson, S Syal, P Schedl, G Deshpande PLoS genetics 18 (1), e1010002, 2022 | 9 | 2022 |
Optogenetic rescue of a developmental patterning mutant HE Johnson, SY Shvartsman, JE Toettcher BioRxiv, 776120, 2019 | 6 | 2019 |
Quantitative Analysis of Phosphoinositide 3‐Kinase (PI3K) Signaling Using Live‐Cell Total Internal Reflection Fluorescence (TIRF) Microscopy HE Johnson, JM Haugh Current Protocols in Cell Biology 61 (1), 14.14. 1-14.14. 24, 2013 | 6 | 2013 |
Are filopodia privileged signaling structures in migrating cells? HE Johnson, JM Haugh Biophysical journal 111 (9), 1827-1830, 2016 | 5 | 2016 |
Dynamics of an incoherent feedforward loop drive ERK-dependent pattern formation in the early Drosophila embryo EK Ho, HR Oatman, SE McFann, L Yang, HE Johnson, SY Shvartsman, ... Development 150 (17), dev201818, 2023 | 3 | 2023 |
Lysophosphatidic acid provokes fibroblast chemotaxis through combinatorial regulation of myosin II SB Asokan, HE Johnson, JD Sondek, MS Shutova, TM Svitkina, ... bioRxiv, 355610, 2018 | 2 | 2018 |
Application of Optogenetics to Probe the Signaling Dynamics of Cell Fate Decision-Making HE Johnson Computational Modeling of Signaling Networks, 315-326, 2023 | 1 | 2023 |
The Duty of an Intracellular Signal: Illuminating Calcium’s Role in Transcriptional Control HE Johnson, JE Toettcher Cell Systems 2 (4), 223-224, 2016 | | 2016 |