The molecular language of membraneless organelles E Gomes, J Shorter Journal of Biological Chemistry 294 (18), 7115-7127, 2019 | 728 | 2019 |
RNA binding antagonizes neurotoxic phase transitions of TDP-43 JR Mann, AM Gleixner, JC Mauna, E Gomes, MR DeChellis-Marks, ... Neuron 102 (2), 321-338. e8, 2019 | 461 | 2019 |
Poly (ADP-ribose) prevents pathological phase separation of TDP-43 by promoting liquid demixing and stress granule localization L McGurk, E Gomes, L Guo, J Mojsilovic-Petrovic, V Tran, RG Kalb, ... Molecular cell 71 (5), 703-717. e9, 2018 | 390 | 2018 |
TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle TO Vogler, JR Wheeler, ED Nguyen, MP Hughes, KA Britson, E Lester, ... Nature 563 (7732), 508-513, 2018 | 204 | 2018 |
C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy CN Cook, Y Wu, HM Odeh, TF Gendron, K Jansen-West, G Del Rosso, ... Science translational medicine 12 (559), eabb3774, 2020 | 161 | 2020 |
Poly (ADP-ribose) engages the TDP-43 nuclear-localization sequence to regulate granulo-filamentous aggregation L McGurk, E Gomes, L Guo, J Shorter, NM Bonini Biochemistry 57 (51), 6923-6926, 2018 | 34 | 2018 |
Therapeutic genetic variation revealed in diverse Hsp104 homologs ZM March, K Sweeney, H Kim, X Yan, LM Castellano, ME Jackrel, JB Lin, ... elife 9, e57457, 2020 | 26 | 2020 |
Poly (ADP-ribose) modulates phase separation of the ALS-associated protein TDP-43. L McGurk, E Gomes, L Guo, J Mojsilovic-Petrovic, V Tran, RG Kalb, ... MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Poly (ADP-ribose)(PAR) promotes TDP-43 liquid droplet formation but reduces TDP-43 aggregation. E Gomes, L McGurk, L Guo, NM Bonini, J Shorter MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Poly (ADP-ribose) Modulates TDP-43 Aggregation and Phase Transition E Gomes University of Pennsylvania, 2017 | | 2017 |