Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application G Gyimesi, J Pujol-Giménez, Y Kanai, MA Hediger Pflügers Archiv-European Journal of Physiology 472 (9), 1177-1206, 2020 | 84 | 2020 |
Could GLUT12 be a potential therapeutic target in cancer treatment? A preliminary report J Pujol-Gimenez, FP de Heredia, MA Idoate, R Airley, MP Lostao, ... Journal of Cancer 6 (2), 139, 2015 | 42 | 2015 |
Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1 P Kandasamy, I Zlobec, DT Nydegger, J Pujol‐Giménez, R Bhardwaj, ... Molecular oncology 15 (10), 2782-2800, 2021 | 32 | 2021 |
A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters J Pujol-Giménez, MA Hediger, G Gyimesi Scientific Reports 7 (1), 6194, 2017 | 32 | 2017 |
The facilitative glucose transporter GLUT12: what do we know and what would we like to know? J Pujol-Giménez, J Barrenetxe, P González-Muniesa, MP Lostao Journal of physiology and biochemistry 69, 325-333, 2013 | 30 | 2013 |
Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism AB Stergachis, J Pujol‐Giménez, G Gyimesi, D Fuster, G Albano, ... Annals of neurology 85 (6), 921-926, 2019 | 29 | 2019 |
Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds C Manatschal, J Pujol-Gimenez, M Poirier, JL Reymond, MA Hediger, ... Elife 8, e51913, 2019 | 26 | 2019 |
Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods J Pujol-Giménez, A Pérez, AM Reyes, DDF Loo, MP Lostao American Journal of Physiology-Cell Physiology 308 (12), C1008-C1022, 2015 | 26 | 2015 |
Reassessment of the transport mechanism of the human zinc transporter SLC39A2 MC Franz, J Pujol-Giménez, N Montalbetti, M Fernandez-Tenorio, ... Biochemistry 57 (26), 3976-3986, 2018 | 24 | 2018 |
Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2) G Gyimesi, G Albano, DG Fuster, MA Hediger, J Pujol-Giménez Journal of biological chemistry 294 (20), 8046-8063, 2019 | 20 | 2019 |
Expression of the glucose transporter GLUT12 in Alzheimer's disease patients J Pujol-Gimenez, E Martisova, A Perez-Mediavilla, MP Lostao, ... Journal of Alzheimer's Disease 42 (1), 97-101, 2014 | 20 | 2014 |
Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei S Havukainen, J Pujol-Giménez, M Valkonen, A Westerholm-Parvinen, ... Scientific reports 11 (1), 14678, 2021 | 14 | 2021 |
The hydroxyl side chain of a highly conserved serine residue is required for cation selectivity and substrate transport in the glial glutamate transporter GLT-1/SLC1A2 A Simonin, N Montalbetti, G Gyimesi, J Pujol-Giménez, MA Hediger Journal of Biological Chemistry 290 (51), 30464-30474, 2015 | 10 | 2015 |
Functional characterization of a highly specific l-arabinose transporter from Trichoderma reesei S Havukainen, J Pujol-Giménez, M Valkonen, MA Hediger, CP Landowski Microbial cell factories 20, 1-20, 2021 | 9 | 2021 |
Inhibitors of human divalent metal transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 fragment library J Pujol‐Giménez, M Poirier, S Bühlmann, C Schuppisser, R Bhardwaj, ... ChemMedChem 16 (21), 3306-3314, 2021 | 9 | 2021 |
Pyrazolyl-pyrimidones inhibit the function of human solute carrier protein SLC11A2 (hDMT1) by metal chelation M Poirier, J Pujol-Giménez, C Manatschal, S Bühlmann, A Embaby, ... RSC Medicinal Chemistry 11 (9), 1023-1031, 2020 | 6 | 2020 |
The allelic variant A391T of metal ion transporter ZIP8 (SLC39A8) leads to hypotension and enhanced insulin resistance SN Verouti, J Pujol-Giménez, P Bermudez-Lekerika, L Scherler, ... Frontiers in physiology 13, 912277, 2022 | 3 | 2022 |
Applications of the Microscale Thermophoresis Binding Assay in COVID-19 Research DT Nydegger, J Pujol-Giménez, P Kandasamy, B Vogt, MA Hediger Viruses 15 (7), 1432, 2023 | 2 | 2023 |
New Insights into the Physiology of Iron Transport: An Interdisciplinary Approach J Zaugg, J Pujol Gimenez, RS Cabra, W Hofstetter, M Hediger, C Albrecht Chimia 76 (12), 996-1004, 2022 | 2 | 2022 |
Dominant‐negative variant in SLC1A4 causes an autosomal dominant epilepsy syndrome J Pujol‐Giménez, G Mirzaa, EE Blue, G Albano, DE Miller, A Allworth, ... Annals of Clinical and Translational Neurology 10 (6), 1046-1053, 2023 | 1 | 2023 |