Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures B Sozen, G Amadei, A Cox, R Wang, E Na, S Czukiewska, L Chappell, ... Nature cell biology 20 (8), 979-989, 2018 | 341 | 2018 |
Phosphoinositide Metabolism Links cGMP-Dependent Protein Kinase G to Essential Ca2+ Signals at Key Decision Points in the Life Cycle of Malaria Parasites M Brochet, MO Collins, TK Smith, E Thompson, S Sebastian, K Volkmann, ... PLoS biology 12 (3), e1001806, 2014 | 221 | 2014 |
A knockout screen of ApiAP2 genes reveals networks of interacting transcriptional regulators controlling the Plasmodium life cycle K Modrzynska, C Pfander, L Chappell, L Yu, C Suarez, K Dundas, ... Cell host & microbe 21 (1), 11-22, 2017 | 212 | 2017 |
Single-cell (multi) omics technologies L Chappell, AJC Russell, T Voet Annual review of genomics and human genetics 19 (1), 15-41, 2018 | 202 | 2018 |
Vector transmission regulates immune control of Plasmodium virulence PJ Spence, W Jarra, P Lévy, AJ Reid, L Chappell, T Brugat, M Sanders, ... Nature 498 (7453), 228-231, 2013 | 180 | 2013 |
Convergent somatic mutations in metabolism genes in chronic liver disease SWK Ng, FJ Rouhani, SF Brunner, N Brzozowska, SJ Aitken, M Yang, ... Nature 598 (7881), 473-478, 2021 | 122 | 2021 |
The nucleosome landscape of Plasmodium falciparum reveals chromatin architecture and dynamics of regulatory sequences PR Kensche, WAM Hoeijmakers, CG Toenhake, M Bras, L Chappell, ... Nucleic acids research 44 (5), 2110-2124, 2016 | 105 | 2016 |
Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq L Chappell, P Ross, L Orchard, TJ Russell, TD Otto, M Berriman, ... BMC genomics 21, 1-19, 2020 | 94 | 2020 |
Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells F Dhalla, J Baran‐Gale, S Maio, L Chappell, GA Holländer, CP Ponting The EMBO journal 39 (1), e101828, 2020 | 93 | 2020 |
The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites SC Charnaud, MWA Dixon, CQ Nie, L Chappell, PR Sanders, T Nebl, ... PloS one 12 (7), e0181656, 2017 | 56 | 2017 |
RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics A Claessens, LM Harris, S Stanojcic, L Chappell, A Stanton, N Kuk, ... PLoS genetics 14 (7), e1007490, 2018 | 36 | 2018 |
Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum SJ Tarr, O Díaz-Ingelmo, LB Stewart, SE Hocking, L Murray, CW Duffy, ... BMC genomics 19, 1-13, 2018 | 35 | 2018 |
Analysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions SV Siegel, L Chappell, JB Hostetler, C Amaratunga, S Suon, U Böhme, ... Scientific Reports 10 (1), 16667, 2020 | 24 | 2020 |
Clonal diversification and histogenesis of malignant germ cell tumours TRW Oliver, L Chappell, R Sanghvi, L Deighton, N Ansari-Pour, ... Nature Communications 13 (1), 4272, 2022 | 13 | 2022 |
Publisher Correction: Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures. B Sozen, G Amadei, A Cox, R Wang, E Na, S Czukiewska, L Chappell, ... Nature Cell Biology 20 (10), 1229-1229, 2018 | 6 | 2018 |
Plasmodium falciparum schizont stage transcriptome variation among clinical isolates and laboratory-adapted clones SJ Tarr, O Díaz-Ingelmo, LB Stewart, SE Hocking, L Murray, CW Duffy, ... bioRxiv, 329532, 2018 | 4 | 2018 |
The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei A Kelner, M Tinti, MLS Guther, BJ Foth, L Chappell, M Berriman, ... Plos one 13 (7), e0201263, 2018 | 3 | 2018 |
Finding a needle in a haystack L Chappell Nature Reviews Microbiology 10 (7), 446-446, 2012 | 3 | 2012 |
Novel approaches for transcriptome analysis in Plasmodium parasites LVL Chappell University of Cambridge, 2014 | 2 | 2014 |
Found in translation L Chappell Nature Reviews Microbiology 12 (4), 238-238, 2014 | | 2014 |