Complex oscillatory waves emerging from cortical organoids model early human brain network development CA Trujillo, R Gao, PD Negraes, J Gu, J Buchanan, S Preissl, A Wang, ... Cell stem cell 25 (4), 558-569. e7, 2019 | 651 | 2019 |
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals MC Marchetto, H Belinson, Y Tian, BC Freitas, C Fu, KC Vadodaria, ... Molecular psychiatry 22 (6), 820-835, 2017 | 412 | 2017 |
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation CA Thomas, L Tejwani, CA Trujillo, PD Negraes, RH Herai, P Mesci, ... Cell Stem Cell, 2017 | 291 | 2017 |
A human neurodevelopmental model for Williams syndrome T Chailangkarn, CA Trujillo, BC Freitas, B Hrvoj-Mihic, RH Herai, DX Yu, ... Nature, 2016 | 203 | 2016 |
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction ZN Zhang, BC Freitas, H Qian, J Lux, A Acab, CA Trujillo, RH Herai, ... Proceedings of the National Academy of Sciences 113 (12), 3185-3190, 2016 | 168 | 2016 |
DNA and RNA aptamers: from tools for basic research towards therapeutic applications H Ulrich, CA Trujillo, AA Nery, JM Alves, P Majumder, RR Resende, ... Combinatorial chemistry & high throughput screening 9 (8), 619-632, 2006 | 163 | 2006 |
Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ... Cell stem cell 26 (2), 187-204. e10, 2020 | 144 | 2020 |
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment CA Trujillo, ES Rice, NK Schaefer, IA Chaim, EC Wheeler, AA Madrigal, ... Science 371 (6530), eaax2537, 2021 | 128 | 2021 |
Novel perspectives of neural stem cell differentiation: from neurotransmitters to therapeutics CA Trujillo, TT Schwindt, AH Martins, JM Alves, LE Mello, H Ulrich Cytometry Part A: The Journal of the International Society for Advancement …, 2009 | 125 | 2009 |
Altered neuronal network and rescue in a human MECP2 duplication model S Nageshappa, C Carromeu, CA Trujillo, P Mesci, I Espuny-Camacho, ... Molecular Psychiatry 21 (2), 178-88, 2016 | 117 | 2016 |
Brain organoids and the study of neurodevelopment CA Trujillo, AR Muotri Trends in molecular medicine 24 (12), 982-990, 2018 | 113 | 2018 |
Cortical organoids model early brain development disrupted by 16p11. 2 copy number variants in autism J Urresti, P Zhang, P Moran-Losada, NK Yu, PD Negraes, CA Trujillo, ... Molecular psychiatry 26 (12), 7560-7580, 2021 | 81 | 2021 |
Development of the anti-VEGF aptamer to a therapeutic agent for clinical ophthalmology CA Trujillo, AA Nery, JM Alves, AH Martins, H Ulrich Clinical ophthalmology 1 (4), 393-402, 2007 | 65 | 2007 |
New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders P Majumder, CA Trujillo, CG Lopes, RR Resende, KN Gomes, ... Purinergic signalling 3, 317-331, 2007 | 65 | 2007 |
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids CA Trujillo, JW Adams, PD Negraes, C Carromeu, L Tejwani, A Acab, ... EMBO Molecular Medicine, e12523, 2021 | 64 | 2021 |
Modeling Rett syndrome with human patient-specific forebrain organoids AR Gomes, TG Fernandes, SH Vaz, TP Silva, EP Bekman, S Xapelli, ... Frontiers in cell and developmental biology 8, 610427, 2020 | 63 | 2020 |
Kinin‐B2 receptor expression and activity during differentiation of embryonic rat neurospheres AH Martins, JM Alves, CA Trujillo, TT Schwindt, GF Barnabé, FLT Motta, ... Cytometry Part A: The Journal of the International Society for Analytical …, 2008 | 58 | 2008 |
Kinin-B2 receptor activity determines the differentiation fate of neural stem cells CA Trujillo, PD Negraes, TT Schwindt, C Lameu, C Carromeu, AR Muotri, ... Journal of Biological Chemistry 287 (53), 44046-44061, 2012 | 57 | 2012 |
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy PD Negraes, CA Trujillo, NK Yu, W Wu, H Yao, N Liang, JD Lautz, E Kwok, ... Molecular psychiatry 26 (11), 7047-7068, 2021 | 49 | 2021 |
Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells C Lameu, CA Trujillo, TT Schwindt, PD Negraes, MM Pillat, KLP Morais, ... Journal of Biological Chemistry 287 (35), 29690-29701, 2012 | 45 | 2012 |