Microglia states and nomenclature: A field at its crossroads RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ... Neuron 110 (21), 3458-3483, 2022 | 674 | 2022 |
The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ plaques CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ... Cell reports 27 (4), 1293-1306. e6, 2019 | 634 | 2019 |
Spatial transcriptomics and in situ sequencing to study Alzheimer’s disease WT Chen, A Lu, K Craessaerts, B Pavie, CS Frigerio, N Corthout, X Qian, ... Cell 182 (4), 976-991. e19, 2020 | 601 | 2020 |
Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology A Olmos-Alonso, STT Schetters, S Sri, K Askew, R Mancuso, ... Brain 139 (3), 891-907, 2016 | 488 | 2016 |
Microglia require CD4 T cells to complete the fetal-to-adult transition E Pasciuto, OT Burton, CP Roca, V Lagou, WD Rajan, T Theys, ... Cell 182 (3), 625-640. e24, 2020 | 251 | 2020 |
Single-nucleus RNA-Seq is not suitable for detection of microglial activation genes in humans N Thrupp, CS Frigerio, L Wolfs, NG Skene, N Fattorelli, S Poovathingal, ... Cell reports 32 (13), 2020 | 241 | 2020 |
Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology A Sierksma, A Lu, R Mancuso, N Fattorelli, N Thrupp, E Salta, J Zoco, ... EMBO molecular medicine 12 (3), e10606, 2020 | 231 | 2020 |
Stem-cell-derived human microglia transplanted in mouse brain to study human disease R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ... Nature neuroscience 22 (12), 2111-2116, 2019 | 221 | 2019 |
Resveratrol improves motoneuron function and extends survival in SOD1G93A ALS mice R Mancuso, J Del Valle, L Modol, A Martinez, AB Granado-Serrano, ... Neurotherapeutics 11 (2), 419-432, 2014 | 199 | 2014 |
Sigma-1R agonist improves motor function and motoneuron survival in ALS mice R Mancuso, S Oliván, A Rando, C Casas, R Osta, X Navarro Neurotherapeutics 9 (4), 814-826, 2012 | 182 | 2012 |
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice R Mancuso, G Fryatt, M Cleal, J Obst, E Pipi, J Monzón-Sandoval, E Ribe, ... Brain 142 (10), 3243-3264, 2019 | 175 | 2019 |
CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves A Martínez-Muriana, R Mancuso, I Francos-Quijorna, A Olmos-Alonso, ... Scientific reports 6 (1), 25663, 2016 | 148 | 2016 |
Inflammatory biomarkers in Alzheimer's disease plasma AR Morgan, S Touchard, C Leckey, C O'Hagan, AJ Nevado-Holgado, ... Alzheimer's & dementia 15 (6), 776-787, 2019 | 143 | 2019 |
Amyotrophic lateral sclerosis: Current perspectives from basic research to the clinic R Mancuso, X Navarro Progress in Neurobiology 133, 1-26, 2015 | 132 | 2015 |
Randall-Selitto test: a new approach for the detection of neuropathic pain after spinal cord injury E Santos-Nogueira, E Redondo Castro, R Mancuso, X Navarro Journal of neurotrauma 29 (5), 898-904, 2012 | 132 | 2012 |
Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis C Casas, M Herrando‐Grabulosa, R Manzano, R Mancuso, R Osta, ... Brain and behavior 3 (2), 145-158, 2013 | 88 | 2013 |
Electrophysiological analysis of a murine model of motoneuron disease R Mancuso, E Santos-Nogueira, R Osta, X Navarro Clinical neurophysiology 122 (8), 1660-1670, 2011 | 81 | 2011 |
Evolution of gait abnormalities in SOD1G93A transgenic mice R Mancuso, S Oliván, R Osta, X Navarro Brain research 1406, 65-73, 2011 | 74 | 2011 |
Sigma receptor agonist 2-(4-morpholinethyl) 1 phenylcyclohexanecarboxylate (Pre084) increases GDNF and BiP expression and promotes neuroprotection after root avulsion injury C Penas, A Pascual-Font, R Mancuso, J Forés, C Casas, X Navarro Journal of neurotrauma 28 (5), 831-840, 2011 | 69 | 2011 |
Stem-cell-derived human microglia transplanted into mouse brain to study human disease N Fattorelli, A Martinez-Muriana, L Wolfs, I Geric, B De Strooper, ... Nature protocols 16 (2), 1013-1033, 2021 | 63 | 2021 |