Using OrthoMCL to assign proteins to OrthoMCL‐DB groups or to cluster proteomes into new ortholog groups S Fischer, BP Brunk, F Chen, X Gao, OS Harb, JB Iodice, D Shanmugam, ... Current protocols in bioinformatics 35 (1), 6.12. 1-6.12. 19, 2011 | 481 | 2011 |
Genomic-scale prioritization of drug targets: the TDR Targets database F Agüero, B Al-Lazikani, M Aslett, M Berriman, FS Buckner, RK Campbell, ... Nature reviews Drug discovery 7 (11), 900-907, 2008 | 361 | 2008 |
Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy AJ Reid, SJ Vermont, JA Cotton, D Harris, GA Hill-Cawthorne, ... PLoS pathogens 8 (3), e1002567, 2012 | 264 | 2012 |
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites YH Woo, H Ansari, TD Otto, CM Klinger, M Kolisko, J Michálek, A Saxena, ... elife 4, e06974, 2015 | 222 | 2015 |
Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach GJ Crowther, D Shanmugam, SJ Carmona, MA Doyle, C Hertz-Fowler, ... PLoS neglected tropical diseases 4 (8), e804, 2010 | 192 | 2010 |
TDR Targets: a chemogenomics resource for neglected diseases MP Magariños, SJ Carmona, GJ Crowther, SA Ralph, DS Roos, ... Nucleic acids research 40 (D1), D1118-D1127, 2012 | 154 | 2012 |
Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic … RS Coyne, L Hannick, D Shanmugam, JB Hostetler, D Brami, VS Joardar, ... Genome Biology 12, 1-26, 2011 | 138 | 2011 |
Widespread occurrence of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) gene haplotype SVMNT in P. falciparum malaria in India PG Vathsala, A Pramanik, S Dhanasekaran, CU Devi, CR Pillai, ... American Journal of Tropical Medicine and Hygiene 70 (3), 256-259, 2004 | 109 | 2004 |
Import of host δ-aminolevulinate dehydratase into the malarial parasite: identification of a new drug target ZQ Bonday, S Dhanasekaran, PN Rangarajan, G Padmanaban Nature medicine 6 (8), 898-903, 2000 | 107 | 2000 |
δ-Aminolevulinic acid dehydratase from Plasmodium falciparum: indigenous versus imported S Dhanasekaran, NR Chandra, BKC Sagar, PN Rangarajan, ... Journal of Biological Chemistry 279 (8), 6934-6942, 2004 | 91 | 2004 |
Involvement of δ-aminolaevulinate synthase encoded by the parasite gene in de novo haem synthesis by Plasmodium falciparum S Varadharajan, S Dhanasekaran, ZQ Bonday, PN Rangarajan, ... Biochemical Journal 367 (2), 321-327, 2002 | 87 | 2002 |
A novel multifunctional oligonucleotide microarray for Toxoplasma gondii A Bahl, PH Davis, M Behnke, F Dzierszinski, M Jagalur, F Chen, ... BMC genomics 11, 1-18, 2010 | 75 | 2010 |
The search for the missing link: a relic plastid in Perkinsus? JAF Robledo, E Caler, M Matsuzaki, PJ Keeling, D Shanmugam, DS Roos, ... International journal for parasitology 41 (12), 1217-1229, 2011 | 72 | 2011 |
Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii A Shukla, KL Olszewski, M Llinás, LM Rommereim, BA Fox, DJ Bzik, ... International journal for parasitology 48 (12), 955-968, 2018 | 51 | 2018 |
TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration L Urán Landaburu, AJ Berenstein, S Videla, P Maru, D Shanmugam, ... Nucleic acids research 48 (D1), D992-D1005, 2020 | 47 | 2020 |
Specific stereoisomeric conformations determine the drug potency of cladosporin scaffold against malarial parasite P Das, P Babbar, N Malhotra, M Sharma, GR Jachak, RG Gonnade, ... Journal of Medicinal Chemistry 61 (13), 5664-5678, 2018 | 47 | 2018 |
Highly diverged novel subunit composition of apicomplexan F-type ATP synthase identified from Toxoplasma gondii R Salunke, T Mourier, M Banerjee, A Pain, D Shanmugam PLoS Biology 16 (7), e2006128, 2018 | 39 | 2018 |
Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules CR Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni ... mSphere 3 (1), pii: e00534-17, 2018 | 32* | 2018 |
Plastid-associated porphobilinogen synthase from Toxoplasma gondii: kinetic and structural properties validate therapeutic potential D Shanmugam, B Wu, U Ramirez, EK Jaffe, DS Roos Journal of Biological Chemistry 285 (29), 22122-22131, 2010 | 31 | 2010 |
Antitumor Effects of Ir(III)-2H-Indazole Complexes for Triple Negative Breast Cancer RL Panchangam, RN Rao, MM Balamurali, TB Hingamire, D Shanmugam, ... Inorganic Chemistry 60 (23), 17593-17607, 2021 | 29 | 2021 |