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Valeria Orrù
Valeria Orrù
IRGB-CNR
在 irgb.cnr.it 的电子邮件经过验证
标题
引用次数
引用次数
年份
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen, G Datta, ...
Nature genetics 51 (2), 237-244, 2019
15512019
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
T Vang, M Congia, MD Macis, L Musumeci, V Orrú, P Zavattari, K Nika, ...
Nature genetics 37 (12), 1317-1319, 2005
8942005
Overexpression of the cytokine BAFF and autoimmunity risk
M Steri, V Orrù, ML Idda, M Pitzalis, M Pala, I Zara, C Sidore, V Faà, ...
New England Journal of Medicine 376 (17), 1615-1626, 2017
3812017
Genetic variants regulating immune cell levels in health and disease
V Orrù, M Steri, G Sole, C Sidore, F Virdis, M Dei, S Lai, M Zoledziewska, ...
Cell 155 (1), 242-256, 2013
3772013
Complex genetic signatures in immune cells underlie autoimmunity and inform therapy
V Orrù, M Steri, C Sidore, M Marongiu, V Serra, S Olla, G Sole, S Lai, ...
Nature genetics 52 (10), 1036-1045, 2020
3252020
The longitudinal dynamics and natural history of clonal haematopoiesis
MA Fabre, JG de Almeida, E Fiorillo, E Mitchell, A Damaskou, J Rak, ...
Nature 606 (7913), 335-342, 2022
1982022
Genetic diversity fuels gene discovery for tobacco and alcohol use
GRB Saunders, X Wang, F Chen, SK Jang, M Liu, C Wang, S Gao, ...
Nature 612 (7941), 720-724, 2022
1662022
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus
V Orru, SJ Tsai, B Rueda, E Fiorillo, SM Stanford, J Dasgupta, J Hartiala, ...
Human molecular genetics 18 (3), 569-579, 2009
1512009
Gold (I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study
D Krishnamurthy, MR Karver, E Fiorillo, V Orru, SM Stanford, N Bottini, ...
Journal of medicinal chemistry 51 (15), 4790-4795, 2008
1472008
Genetic variants in mRNA untranslated regions
M Steri, ML Idda, MB Whalen, V Orrù
Wiley Interdisciplinary Reviews: RNA 9 (4), e1474, 2018
1462018
Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue
E Fiorillo, V Orru, SM Stanford, Y Liu, M Salek, N Rapini, AD Schenone, ...
Journal of biological chemistry 285 (34), 26506-26518, 2010
1192010
Number of autoantibodies and HLA genotype, more than high titers of glutamic acid decarboxylase autoantibodies, predict insulin dependence in latent autoimmune diabetes of adults
M Maioli, GM Pes, G Delitala, L Puddu, A Falorni, F Tolu, R Lampis, ...
European journal of endocrinology 163 (4), 541-549, 2010
1012010
Further Evidence of a Primary, Causal Association of the PTPN22 620W Variant With Type 1 Diabetes
M Zoledziewska, C Perra, V Orru, L Moi, P Frongia, M Congia, N Bottini, ...
Diabetes 57 (1), 229-234, 2008
622008
Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation
SJ Tsai, U Sen, L Zhao, WB Greenleaf, J Dasgupta, E Fiorillo, V Orrú, ...
Biochemistry 48 (22), 4838-4845, 2009
592009
Depressive symptoms, thyroid hormone and autoimmunity in a population-based cohort from Sardinia
AP Delitala, A Terracciano, E Fiorillo, V Orrù, D Schlessinger, F Cucca
Journal of affective disorders 191, 82-87, 2016
482016
CXCR3 identifies human naive CD8+ T cells with enhanced effector differentiation potential
G De Simone, E Mazza, A Cassotta, AN Davydov, M Kuka, V Zanon, ...
The Journal of Immunology 203 (12), 3179-3189, 2019
422019
Effect of different disease-modifying therapies on humoral response to BNT162b2 vaccine in Sardinian multiple sclerosis patients
M Pitzalis, ML Idda, V Lodde, A Loizedda, M Lobina, M Zoledziewska, ...
Frontiers in immunology 12, 781843, 2021
412021
Genetic loci linked to type 1 diabetes and multiple sclerosis families in Sardinia
M Pitzalis, P Zavattari, R Murru, E Deidda, M Zoledziewska, D Murru, ...
BMC Medical Genetics 9, 1-10, 2008
352008
Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells …
RC Ferreira, X Castro Dopico, JJ Oliveira, DB Rainbow, JH Yang, ...
Frontiers in Immunology 10, 2606, 2019
332019
Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells
DJ Wu, W Zhou, S Enouz, V Orru, SM Stanford, CJ Maine, N Rapini, ...
PLoS One 9 (2), e86677, 2014
332014
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