In vivo overexpression of frataxin causes toxicity mediated by iron-sulfur cluster deficiency C Huichalaf, TL Perfitt, A Kuperman, R Gooch, RC Kovi, KA Brenneman, ... Molecular Therapy-Methods & Clinical Development 24, 367-378, 2022 | 42 | 2022 |
Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review H Bolland, TS Ma, S Ramlee, K Ramadan, EM Hammond Biochemical Society Transactions 49 (3), 1251-1263, 2021 | 36 | 2021 |
Hypoxia-induced SETX links replication stress with the unfolded protein response S Ramachandran, TS Ma, J Griffin, N Ng, IP Foskolou, MS Hwang, ... Nature Communications 12 (1), 3686, 2021 | 33 | 2021 |
4′-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function JD Majmudar, X Feng, NG Fox, JF Nabhan, T Towle, T Ma, R Gooch, ... MedChemComm 10 (2), 209-220, 2019 | 31 | 2019 |
Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity SB Bader, TS Ma, CJ Simpson, J Liang, SEB Maezono, MM Olcina, ... Nucleic acids research 49 (13), 7492-7506, 2021 | 27 | 2021 |
The predictive value of G8 and the Cancer and aging research group chemotherapy toxicity tool in treatment-related toxicity in older Chinese patients with cancer WL Chan, T Ma, KL Cheung, H Choi, J Wong, KO Lam, KK Yuen, MY Luk, ... Journal of Geriatric Oncology 12 (4), 557-562, 2021 | 17 | 2021 |
Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops TS Ma, KR Worth, C Maher, N Ng, C Beghè, N Gromak, AM Rose, ... Nucleic acids research 51 (21), 11584-11599, 2023 | 6 | 2023 |
REACTIVE OXYGEN SPECIES, PROTEIN TRAPPING AND CANCER: NOVEL INSIGHTS FROM IN VITRO STUDIES A Rose, T Goncalves, T Ma, A Rose, S Cunniffe, T Humphrey, ... PEDIATRIC BLOOD & CANCER 70, 2023 | | 2023 |
New Insights into the Toxicity of AAV-Mediated Overexpression of Frataxin C Huichalaf, TL Perfitt, A Kuperman, R Gooch, RC Kovi, K Brenneman, ... MOLECULAR THERAPY 30 (4), 365-365, 2022 | | 2022 |
Links between the unfolded protein response and the DNA damage response in hypoxia TS Ma University of Oxford, 2022 | | 2022 |
Transient Correction of the Phenotype in a Cardiac Mouse Model of Friedreich Ataxia Using AAV9-CAG-FXN: Toxic Effect of Supraphysiological Expression of the Frataxin Transgene A Martelli, X Chen, B Assaf, T Ma, T Franks, W Laurence, R Gooch, ... MOLECULAR THERAPY 28 (4), 264-264, 2020 | | 2020 |
Preclinical Evaluation of an AAV-Based Gene Therapy Approach for the Treatment of Friedreich Ataxia Cardiomyopathy A Martelli, BT Assaf, R Gooch, T Ma, LO Whiteley, C Bulawa MOLECULAR THERAPY 27 (4), 51-51, 2019 | | 2019 |
Selective Repression of C9ORF72 Repeat Expansion-Containing Transcripts for the Treatment of ALS M Samie, A Pattamatta, D Baldwin, S Hinkley, E Tait, N Scarlott, T Ma, ... MOLECULAR THERAPY 27 (4), 260-261, 2019 | | 2019 |
Prospective Evaluation of the G8 Screening Tool for Predicting Treatment-related Toxicities in Chinese Elderly Cancer Patients WLW Chan, J Wong, T Ma, CW Choi, KO Lam, VHF Lee, KK Yuen, ... International Society of Geriatric Oncology (SIOG) Annual Meeting, 2019 | | 2019 |