Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms CP Randall, A Gupta, N Jackson, D Busse, AJ O'Neill Journal of Antimicrobial Chemotherapy 70 (4), 1037-1046, 2015 | 275 | 2015 |
The target of daptomycin is absent from Escherichia coli and other Gram-negative pathogens CP Randall, KR Mariner, I Chopra, AJ O'Neill Antimicrobial agents and chemotherapy 57 (1), 637-639, 2013 | 191 | 2013 |
The silver cation (Ag+): antistaphylococcal activity, mode of action and resistance studies CP Randall, LB Oyama, JM Bostock, I Chopra, AJ O'Neill Journal of Antimicrobial Chemotherapy 68 (1), 131-138, 2013 | 153 | 2013 |
XF-70 and XF-73, novel antibacterial agents active against slow-growing and non-dividing cultures of Staphylococcus aureus including biofilms N Ooi, K Miller, C Randall, W Rhys-Williams, W Love, I Chopra Journal of antimicrobial chemotherapy 65 (1), 72-78, 2009 | 116 | 2009 |
In vitro studies indicate a high resistance potential for the lantibiotic nisin in Staphylococcus aureus and define a genetic basis for nisin resistance KL Blake, CP Randall, AJ O'Neill Antimicrobial agents and chemotherapy 55 (5), 2362-2368, 2011 | 99 | 2011 |
Structure–activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF M Hrast, S Turk, I Sosič, D Knez, CP Randall, H Barreteau, ... European Journal of medicinal chemistry 66, 32-45, 2013 | 58 | 2013 |
Transient Silencing of Antibiotic Resistance by Mutation Represents a Significant Potential Source of Unanticipated Therapeutic Failure L Kime, CP Randall, FI Banda, F Coll, J Wright, J Richardson, J Empel, ... mBio 10 (5), e01755-19, 2019 | 46 | 2019 |
Impact of exposure of methicillin-resistant Staphylococcus aureus to polyhexanide in vitro and in vivo A Renzoni, E Von Dach, C Landelle, SM Diene, C Manzano, R Gonzales, ... Antimicrobial Agents and Chemotherapy 61 (10), e00272-17, 2017 | 40 | 2017 |
Cryptic silver resistance is prevalent and readily activated in certain Gram-negative pathogens E Elkrewi, CP Randall, N Ooi, JL Cottell, AJ O’neill Journal of Antimicrobial Chemotherapy 72 (11), 3043-3046, 2017 | 38 | 2017 |
Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold M Hrast, M Anderluh, D Knez, CP Randall, H Barreteau, AJ O'Neill, ... European Journal of Medicinal Chemistry 73, 83-96, 2014 | 38 | 2014 |
Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of γ-actinorhodin NM Nass, S Farooque, C Hind, ME Wand, CP Randall, JM Sutton, ... Scientific reports 7 (1), 17419, 2017 | 27 | 2017 |
6-Arylpyrido[2,3-d]pyrimidines as Novel ATP-Competitive Inhibitors of Bacterial D-Alanine:D-Alanine Ligase V Škedelj, E Arsovska, T Tomašić, A Kroflič, V Hodnik, M Hrast, ... Public Library of Science 7 (8), e39922, 2012 | 27 | 2012 |
Acquired Nisin Resistance in Staphylococcus aureus Involves Constitutive Activation of an Intrinsic Peptide Antibiotic Detoxification Module CP Randall, A Gupta, B Utley-Drew, SY Lee, G Morrison-Williams, ... mSphere 3 (6), e00633-18, 2018 | 25* | 2018 |
Targeting Multiple Aminoacyl-tRNA Synthetases Overcomes the Resistance Liabilities Associated with Antibacterial Inhibitors Acting on a Single Such Enzyme CP Randall, D Rasina, A Jirgensons, AJ O'Neill Antimicrobial agents and chemotherapy 60 (10), 6359-6361, 2016 | 24 | 2016 |
N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors MH Charlton, R Aleksis, A Saint-Leger, A Gupta, E Loza, ... ACS Medicinal Chemistry Letters 9 (2), 84-88, 2018 | 18 | 2018 |
A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus aureus A Gupta, C Monteferrante, D Rasina, G Leitis, CP Randall, JH Tomlinson, ... Antimicrobial Agents and Chemotherapy 60 (5), 3219-3221, 2016 | 9 | 2016 |
A platform for detecting cross-resistance in antibacterial drug discovery LH Galarion, M Mohamad, Z Alzeyadi, CP Randall, AJ O’Neill Journal of Antimicrobial Chemotherapy 76 (6), 1467-1471, 2021 | 3 | 2021 |
The Silver Cation (Ag+): Antibacterial Mode of Action and Mechanisms of Resistance CP Randall University of Leeds (School of Molecular and Cellular Biology, Faculty of …, 2013 | 2 | 2013 |
An extensively validated whole-cell biosensor for specific, sensitive and high-throughput detection of antibacterial inhibitors targeting cell-wall biosynthesis LH Galarion, JK Mitchell, CP Randall, AJ O’Neill Journal of Antimicrobial Chemotherapy 78 (3), 646-655, 2023 | 1 | 2023 |
Transient silencing of antibiotic resistance by mutation represents a significant potential source of unanticipated therapeutic failure. mBio 10: e01755-19 L Kime, CP Randall, FI Banda, F Coll, J Wright, J Richardson, J Empel, ... | | 2019 |