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Christopher Randall
Christopher Randall
Associate Professor of Microbiology, University of Leeds
在 leeds.ac.uk 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms
CP Randall, A Gupta, N Jackson, D Busse, AJ O'Neill
Journal of Antimicrobial Chemotherapy 70 (4), 1037-1046, 2015
2752015
The target of daptomycin is absent from Escherichia coli and other Gram-negative pathogens
CP Randall, KR Mariner, I Chopra, AJ O'Neill
Antimicrobial agents and chemotherapy 57 (1), 637-639, 2013
1912013
The silver cation (Ag+): antistaphylococcal activity, mode of action and resistance studies
CP Randall, LB Oyama, JM Bostock, I Chopra, AJ O'Neill
Journal of Antimicrobial Chemotherapy 68 (1), 131-138, 2013
1532013
XF-70 and XF-73, novel antibacterial agents active against slow-growing and non-dividing cultures of Staphylococcus aureus including biofilms
N Ooi, K Miller, C Randall, W Rhys-Williams, W Love, I Chopra
Journal of antimicrobial chemotherapy 65 (1), 72-78, 2009
1162009
In vitro studies indicate a high resistance potential for the lantibiotic nisin in Staphylococcus aureus and define a genetic basis for nisin resistance
KL Blake, CP Randall, AJ O'Neill
Antimicrobial agents and chemotherapy 55 (5), 2362-2368, 2011
992011
Structure–activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF
M Hrast, S Turk, I Sosič, D Knez, CP Randall, H Barreteau, ...
European Journal of medicinal chemistry 66, 32-45, 2013
582013
Transient Silencing of Antibiotic Resistance by Mutation Represents a Significant Potential Source of Unanticipated Therapeutic Failure
L Kime, CP Randall, FI Banda, F Coll, J Wright, J Richardson, J Empel, ...
mBio 10 (5), e01755-19, 2019
462019
Impact of exposure of methicillin-resistant Staphylococcus aureus to polyhexanide in vitro and in vivo
A Renzoni, E Von Dach, C Landelle, SM Diene, C Manzano, R Gonzales, ...
Antimicrobial Agents and Chemotherapy 61 (10), e00272-17, 2017
402017
Cryptic silver resistance is prevalent and readily activated in certain Gram-negative pathogens
E Elkrewi, CP Randall, N Ooi, JL Cottell, AJ O’neill
Journal of Antimicrobial Chemotherapy 72 (11), 3043-3046, 2017
382017
Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold
M Hrast, M Anderluh, D Knez, CP Randall, H Barreteau, AJ O'Neill, ...
European Journal of Medicinal Chemistry 73, 83-96, 2014
382014
Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of γ-actinorhodin
NM Nass, S Farooque, C Hind, ME Wand, CP Randall, JM Sutton, ...
Scientific reports 7 (1), 17419, 2017
272017
6-Arylpyrido[2,3-d]pyrimidines as Novel ATP-Competitive Inhibitors of Bacterial D-Alanine:D-Alanine Ligase
V Škedelj, E Arsovska, T Tomašić, A Kroflič, V Hodnik, M Hrast, ...
Public Library of Science 7 (8), e39922, 2012
272012
Acquired Nisin Resistance in Staphylococcus aureus Involves Constitutive Activation of an Intrinsic Peptide Antibiotic Detoxification Module
CP Randall, A Gupta, B Utley-Drew, SY Lee, G Morrison-Williams, ...
mSphere 3 (6), e00633-18, 2018
25*2018
Targeting Multiple Aminoacyl-tRNA Synthetases Overcomes the Resistance Liabilities Associated with Antibacterial Inhibitors Acting on a Single Such Enzyme
CP Randall, D Rasina, A Jirgensons, AJ O'Neill
Antimicrobial agents and chemotherapy 60 (10), 6359-6361, 2016
242016
N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors
MH Charlton, R Aleksis, A Saint-Leger, A Gupta, E Loza, ...
ACS Medicinal Chemistry Letters 9 (2), 84-88, 2018
182018
A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus aureus
A Gupta, C Monteferrante, D Rasina, G Leitis, CP Randall, JH Tomlinson, ...
Antimicrobial Agents and Chemotherapy 60 (5), 3219-3221, 2016
92016
A platform for detecting cross-resistance in antibacterial drug discovery
LH Galarion, M Mohamad, Z Alzeyadi, CP Randall, AJ O’Neill
Journal of Antimicrobial Chemotherapy 76 (6), 1467-1471, 2021
32021
The Silver Cation (Ag+): Antibacterial Mode of Action and Mechanisms of Resistance
CP Randall
University of Leeds (School of Molecular and Cellular Biology, Faculty of …, 2013
22013
An extensively validated whole-cell biosensor for specific, sensitive and high-throughput detection of antibacterial inhibitors targeting cell-wall biosynthesis
LH Galarion, JK Mitchell, CP Randall, AJ O’Neill
Journal of Antimicrobial Chemotherapy 78 (3), 646-655, 2023
12023
Transient silencing of antibiotic resistance by mutation represents a significant potential source of unanticipated therapeutic failure. mBio 10: e01755-19
L Kime, CP Randall, FI Banda, F Coll, J Wright, J Richardson, J Empel, ...
2019
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