OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin K Keusekotten, PR Elliott, L Glockner, BK Fiil, RB Damgaard, Y Kulathu, ... Cell 153 (6), 1312-1326, 2013 | 478 | 2013 |
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ... Molecular cell 46 (6), 746-758, 2012 | 407 | 2012 |
The deubiquitinase OTULIN is an essential negative regulator of inflammation and autoimmunity RB Damgaard, JA Walker, P Marco-Casanova, NV Morgan, ... Cell 166 (5), 1215-1230. e20, 2016 | 304 | 2016 |
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling BK Fiil, RB Damgaard, SA Wagner, K Keusekotten, M Fritsch, ... Molecular cell 50 (6), 818-830, 2013 | 266 | 2013 |
XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation M Yabal, N Müller, H Adler, N Knies, CJ Groß, RB Damgaard, ... Cell reports 7 (6), 1796-1808, 2014 | 259 | 2014 |
X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis C Speckmann, K Lehmberg, MH Albert, RB Damgaard, M Fritsch, ... Clinical immunology 149 (1), 133-141, 2013 | 183 | 2013 |
CYLD limits Lys63-and Met1-linked ubiquitin at receptor complexes to regulate innate immune signaling M Hrdinka, BK Fiil, M Zucca, D Leske, K Bagola, M Yabal, PR Elliott, ... Cell reports 14 (12), 2846-2858, 2016 | 154 | 2016 |
Disease‐causing mutations in the XIAP BIR 2 domain impair NOD 2‐dependent immune signalling RB Damgaard, BK Fiil, C Speckmann, M Yabal, U Stadt, S Bekker‐Jensen, ... EMBO molecular medicine 5 (8), 1278-1295, 2013 | 151 | 2013 |
Apoptotic cell death in disease—Current understanding of the NCCD 2023 I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 30 (5), 1097-1154, 2023 | 108 | 2023 |
The ubiquitin system: from cell signalling to disease biology and new therapeutic opportunities RB Damgaard Cell Death & Differentiation 28 (2), 423-426, 2021 | 107 | 2021 |
Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity RB Damgaard, M Gyrd-Hansen Discovery medicine 11 (58), 221-231, 2011 | 99 | 2011 |
OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death RB Damgaard, PR Elliott, KN Swatek, ER Maher, P Stepensky, O Elpeleg, ... EMBO molecular medicine 11 (3), e9324, 2019 | 93 | 2019 |
OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer RB Damgaard, HE Jolin, MED Allison, SE Davies, HL Titheradge, ... Cell Death & Differentiation 27 (5), 1457-1474, 2020 | 53 | 2020 |
Met1-linked ubiquitin signalling in health and disease: inflammation, immunity, cancer, and beyond AS Jahan, CR Elbæk, RB Damgaard Cell Death & Differentiation 28 (2), 473-492, 2021 | 42 | 2021 |
WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity CR Elbæk, V Petrosius, J Benada, L Erichsen, RB Damgaard, ... Cell reports 38 (3), 2022 | 32 | 2022 |
Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5 L Merklinger, J Bauer, PA Pedersen, RB Damgaard, JP Morth Life Science Alliance 5 (8), 2022 | 7 | 2022 |
Ester‐linked ubiquitination by HOIL‐1 controls immune signalling by shaping the linear ubiquitin landscape JN Pruneda, RB Damgaard The FEBS Journal 288 (20), 5903-5908, 2021 | 6 | 2021 |
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62 N Furthmann, V Bader, L Angersbach, A Blusch, S Goel, ... Nature Communications 14 (1), 8368, 2023 | 5* | 2023 |
Legionella dismantles linear ubiquitin RB Damgaard, JN Pruneda Nature Microbiology 4 (8), 1244-1245, 2019 | 2 | 2019 |
Universiteterne har brug for en reformpause K Kropp, K Vallgårda, AH Laustsen-Kiel, N Albrechtsen, L Sylow, ... Berlingske Tidende, 2023 | | 2023 |