Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism LA Barclay, TE Wales, TP Garner, F Wachter, S Lee, RM Guerra, ... Molecular cell 57 (5), 873-886, 2015 | 157 | 2015 |
Selective covalent targeting of anti-apoptotic BFL-1 by cysteine-reactive stapled peptide inhibitors AJ Huhn, RM Guerra, EP Harvey, GH Bird, LD Walensky Cell chemical biology 23 (9), 1123-1134, 2016 | 75 | 2016 |
Crystal structures of anti-apoptotic BFL-1 and its complex with a covalent stapled peptide inhibitor EP Harvey, HS Seo, RM Guerra, GH Bird, S Dhe-Paganon, LD Walensky Structure 26 (1), 153-160. e4, 2018 | 58 | 2018 |
Coenzyme Q biochemistry and biosynthesis RM Guerra, DJ Pagliarini Trends in biochemical sciences 48 (5), 463-476, 2023 | 55 | 2023 |
Identification of a covalent molecular inhibitor of anti-apoptotic BFL-1 by disulfide tethering EP Harvey, ZJ Hauseman, DT Cohen, TJ Rettenmaier, S Lee, AJ Huhn, ... Cell chemical biology 27 (6), 647-656. e6, 2020 | 37 | 2020 |
Precision targeting of BFL-1/A1 and an ATM co-dependency in human cancer RM Guerra, GH Bird, EP Harvey, NV Dharia, KJ Korshavn, MS Prew, ... Cell reports 24 (13), 3393-3403. e5, 2018 | 26 | 2018 |
Structure and functionality of a multimeric human COQ7: COQ9 complex M Manicki, H Aydin, LA Abriata, KA Overmyer, RM Guerra, JJ Coon, ... Molecular cell 82 (22), 4307-4323. e10, 2022 | 25 | 2022 |
Challenges in targeting a basic helix–loop–helix transcription factor with hydrocarbon-stapled peptides AL Edwards, DH Meijer, RM Guerra, RJ Molenaar, JA Alberta, F Bernal, ... ACS chemical biology 11 (11), 3146-3153, 2016 | 17 | 2016 |
COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells L Pelosi, L Morbiato, A Burgardt, F Tonello, AK Bartlett, RM Guerra, ... Molecular cell 84 (5), 981-989. e7, 2024 | 10 | 2024 |
Dissecting the role of individual Bcl-2 members in response and resistance to ibrutinib or venetoclax in CLL F Brocco, H ter Burg, S Fernandes, CS Tam, F Forconi, RM Guerra, G Bird, ... Blood 130, 262, 2017 | 7 | 2017 |
TOMM40 and TOMM22 of the Translocase Outer Mitochondrial Membrane Complex rescue statin-impaired mitochondrial dynamics, morphology, and mitophagy in skeletal myotubes NV Yang, S Rogers, R Guerra, DJ Pagliarini, E Theusch, RM Krauss bioRxiv, 2023.06. 24.546411, 2023 | 6 | 2023 |
Systematic analysis of NDUFAF6 in complex I assembly and mitochondrial disease AY Sung, RM Guerra, LH Steenberge, CL Alston, K Murayama, Y Okazaki, ... Nature Metabolism, 1-15, 2024 | 5 | 2024 |
Hem25p is required for mitochondrial IPP transport in fungi J Tai, RM Guerra, SW Rogers, Z Fang, LK Muehlbauer, E Shishkova, ... Nature cell biology 25 (11), 1616-1624, 2023 | 5 | 2023 |
Hem25p is a mitochondrial IPP transporter J Tai, RM Guerra, SW Rogers, Z Fang, LK Muehlbauer, E Shishkova, ... bioRxiv, 2023 | 3 | 2023 |
Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive noxa peptides LD Walensky, GH Bird, R Guerra, E Harvey US Patent 11,834,520, 2023 | 2 | 2023 |
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III B Chen, DC Stark, PV Jadhav, TM Lynn-Nguyen, BS Halligan, ... bioRxiv, 2024.02. 02.578646, 2024 | 1 | 2024 |
Aim18p and Aim46p are chalcone isomerase domain–containing mitochondrial hemoproteins in Saccharomyces cerevisiae JM Schmitz, JF Wolters, NH Murray, RM Guerra, CA Bingman, ... Journal of Biological Chemistry 299 (3), 2023 | 1 | 2023 |
Aim18p and Aim46p are CHI-domain-containing mitochondrial hemoproteins in Saccharomyces cerevisiae JM Schmitz, JF Wolters, NH Murray, RM Guerra, CA Bingman, ... bioRxiv, 2022.11. 15.516536, 2022 | 1 | 2022 |
Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive noxa peptides LD Walensky, GH Bird, R Guerra, E Harvey US Patent App. 18/494,623, 2024 | | 2024 |
Reducing mitochondrial mysteries RM Guerra, DJ Pagliarini Nature Chemical Biology 20 (2), 132-133, 2024 | | 2024 |