| Mitochondrial dysfunction, through impaired autophagy, leads to endoplasmic reticulum stress, deregulated lipid metabolism, and pancreatitis in animal models G Biczo, ET Vegh, N Shalbueva, OA Mareninova, J Elperin, E Lotshaw, ... Gastroenterology 154 (3), 689-703, 2018 | 322 | 2018 |
| Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP R Mukherjee, OA Mareninova, IV Odinokova, W Huang, J Murphy, ... Gut 65 (8), 1333-1346, 2016 | 239 | 2016 |
| Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models L Wen, S Voronina, MA Javed, M Awais, P Szatmary, D Latawiec, ... Gastroenterology 149 (2), 481-492. e7, 2015 | 227 | 2015 |
| Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular … Z Yang, L Zhuang, P Szatmary, L Wen, H Sun, Y Lu, Q Xu, X Chen International journal of medical sciences 12 (3), 256, 2015 | 218 | 2015 |
| Metformin uniquely prevents thrombosis by inhibiting platelet activation and mtDNA release G Xin, Z Wei, C Ji, H Zheng, J Gu, L Ma, W Huang, SL Morris-Natschke, ... Scientific reports 6 (1), 36222, 2016 | 124 | 2016 |
| The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis RT Waldron, Y Chen, H Pham, A Go, HY Su, C Hu, L Wen, SZ Husain, ... The Journal of physiology 597 (12), 3085-3105, 2019 | 115 | 2019 |
| Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1, 4, 5-trisphosphate receptor-mediated Ca2+ release W Huang, MC Cane, R Mukherjee, P Szatmary, X Zhang, V Elliott, ... Gut 66 (2), 301-313, 2017 | 114 | 2017 |
| Transient high pressure in pancreatic ducts promotes inflammation and alters tight junctions via calcineurin signaling in mice L Wen, TA Javed, D Yimlamai, A Mukherjee, X Xiao, SZ Husain Gastroenterology 155 (4), 1250-1263. e5, 2018 | 66 | 2018 |
| Small molecule inhibitors of cyclophilin D to protect mitochondrial function as a potential treatment for acute pancreatitis ER Shore, M Awais, NM Kershaw, RR Gibson, S Pandalaneni, ... Journal of medicinal chemistry 59 (6), 2596-2611, 2016 | 63 | 2016 |
| Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release G Xin, Z Wei, C Ji, H Zheng, J Gu, L Ma, W Huang, SL Morris-Natschke, ... Free Radical Biology and Medicine 108, 247-257, 2017 | 54 | 2017 |
| Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy G Hernandez, T Luo, TA Javed, L Wen, MA Kalwat, K Vale, F Ammouri, ... Science translational medicine 12 (525), eaay5186, 2020 | 50 | 2020 |
| Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: a meta-analysis W Huang, K Altaf, T Jin, JJ Xiong, L Wen, MA Javed, M Johnstone, P Xue, ... World journal of gastroenterology: WJG 19 (28), 4607, 2013 | 45 | 2013 |
| Myeloid‐specific dopamine D2 receptor signalling controls inflammation in acute pancreatitis via inhibiting M1 macrophage X Han, J Ni, Z Wu, J Wu, B Li, X Ye, J Dai, C Chen, J Xue, R Wan, L Wen, ... British journal of pharmacology 177 (13), 2991-3008, 2020 | 44 | 2020 |
| Effects of the mitochondria‐targeted antioxidant mitoquinone in murine acute pancreatitis W Huang, N Cash, L Wen, P Szatmary, R Mukherjee, J Armstrong, ... Mediators of Inflammation 2015 (1), 901780, 2015 | 43 | 2015 |
| TRO40303 ameliorates alcohol-induced pancreatitis through reduction of fatty acid ethyl ester–induced mitochondrial injury and necrotic cell death MA Javed, L Wen, M Awais, D Latawiec, W Huang, M Chvanov, ... Pancreas 47 (1), 18-24, 2018 | 40 | 2018 |
| Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine X Zhang, T Jin, N Shi, L Yao, X Yang, C Han, L Wen, D Du, P Szatmary, ... Frontiers in Physiology 9, 1922, 2019 | 35 | 2019 |
| Targeted inhibition of pancreatic acinar cell calcineurin is a novel strategy to prevent post-ERCP pancreatitis AI Orabi, L Wen, TA Javed, T Le, P Guo, S Sanker, D Ricks, K Boggs, ... Cellular and molecular gastroenterology and hepatology 3 (1), 119-128, 2017 | 33 | 2017 |
| Dihydrodiosgenin protects against experimental acute pancreatitis and associated lung injury through mitochondrial protection and PI3Kγ/Akt inhibition Y Shen, L Wen, R Zhang, Z Wei, N Shi, Q Xiong, Q Xia, Z Xing, Z Zeng, ... British Journal of Pharmacology 175 (10), 1621-1636, 2018 | 30 | 2018 |
| Animal models: challenges and opportunities to determine optimal experimental models of pancreatitis and pancreatic cancer JL Saloman, KM Albers, Z Cruz-Monserrate, BM Davis, M Edderkaoui, ... Pancreas 48 (6), 759-779, 2019 | 29 | 2019 |
| Schisandrin B antagonizes cardiotoxicity induced by pirarubicin by inhibiting mitochondrial permeability transition pore (mPTP) opening and decreasing cardiomyocyte apoptosis H Shi, H Tang, W Ai, Q Zeng, H Yang, F Zhu, Y Wei, R Feng, L Wen, P Pu, ... Frontiers in Pharmacology 12, 733805, 2021 | 28 | 2021 |
