The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B E Reid, J Connell, TL Edwards, S Duley, SE Brown, CM Sanderson Human molecular genetics 14 (1), 19-38, 2005 | 228 | 2005 |
Visual acuity after retinal gene therapy for choroideremia TL Edwards, JK Jolly, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... New England Journal of Medicine 374 (20), 1996-1998, 2016 | 224 | 2016 |
Interim results of a multicenter trial with the new electronic subretinal implant alpha AMS in 15 patients blind from inherited retinal degenerations K Stingl, R Schippert, KU Bartz-Schmidt, D Besch, CL Cottriall, ... Frontiers in neuroscience 11, 445, 2017 | 209 | 2017 |
Spastin and atlastin, two proteins mutated in autosomal-dominant hereditary spastic paraplegia, are binding partners CM Sanderson, JW Connell, TL Edwards, NA Bright, S Duley, ... Human molecular genetics 15 (2), 307-318, 2006 | 198 | 2006 |
First-in-human study of the safety and viability of intraocular robotic surgery TL Edwards, K Xue, HCM Meenink, MJ Beelen, GJL Naus, MP Simunovic, ... Nature Biomedical Engineering, 2018 | 191 | 2018 |
Assessment of the electronic retinal implant alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa TL Edwards, CL Cottriall, K Xue, MP Simunovic, JD Ramsden, E Zrenner, ... Ophthalmology 125 (3), 432-443, 2018 | 179 | 2018 |
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia K Xue, JK Jolly, AR Barnard, A Rudenko, AP Salvetti, MI Patrício, ... Nature medicine 24 (10), 1507-1512, 2018 | 178 | 2018 |
The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling HTH Tsang, TL Edwards, X Wang, JW Connell, RJ Davies, HJ Durrington, ... Human molecular genetics 18 (20), 3805-3821, 2009 | 158 | 2009 |
Prevalence and aetiology of lymphoedema after breast cancer treatment in southern Tasmania TL Edwards Australian and New Zealand Journal of Surgery 70 (6), 412-418, 2000 | 118 | 2000 |
Gene therapy for visual loss: Opportunities and concerns JH Lee, JH Wang, J Chen, F Li, TL Edwards, AW Hewitt, GS Liu Progress in retinal and eye research 68, 31-53, 2019 | 99 | 2019 |
Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5 TL Edwards, VE Clowes, HTH Tsang, JW Connell, CM Sanderson, ... Biochemical journal 423 (1), 31-39, 2009 | 87 | 2009 |
Characterizing the natural history of visual function in choroideremia using microperimetry and multimodal retinal imaging JK Jolly, K Xue, TL Edwards, M Groppe, RE MacLaren Investigative ophthalmology & visual science 58 (12), 5575-5583, 2017 | 85 | 2017 |
Correlation of optical coherence tomography and autofluorescence in the outer retina and choroid of patients with choroideremia K Xue, M Oldani, JK Jolly, TL Edwards, M Groppe, SM Downes, ... Investigative Ophthalmology & Visual Science 57 (8), 3674-3684, 2016 | 81 | 2016 |
The spectrum of CHM gene mutations in choroideremia and their relationship to clinical phenotype MP Simunovic, JK Jolly, K Xue, TL Edwards, M Groppe, SM Downes, ... Investigative ophthalmology & visual science 57 (14), 6033-6039, 2016 | 80 | 2016 |
Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina DG Hickey, TL Edwards, AR Barnard, MS Singh, SR de Silva, ... Gene therapy 24 (12), 787-800, 2017 | 76 | 2017 |
Gene therapy for inherited retinal diseases: progress and possibilities ML Hu, TL Edwards, F O’Hare, DG Hickey, JH Wang, Z Liu, LN Ayton Clinical and Experimental Optometry 104 (4), 444-454, 2021 | 66 | 2021 |
A qualitative and quantitative assessment of fundus autofluorescence patterns in patients with choroideremia JK Jolly, TL Edwards, J Moules, M Groppe, SM Downes, RE MacLaren Investigative ophthalmology & visual science 57 (10), 4498-4503, 2016 | 66 | 2016 |
Correlation of retinal structure and function in choroideremia carriers TL Edwards, M Groppe, JK Jolly, SM Downes, RE MacLaren Ophthalmology 122 (6), 1274-1276, 2015 | 54 | 2015 |
Robot-assisted vitreoretinal surgery: current perspectives M Roizenblatt, TL Edwards, PL Gehlbach Robotic surgery 5, 1-11, 2018 | 46 | 2018 |
The test–retest reliability of the photopic negative response (PhNR) J Tang, T Edwards, JG Crowston, M Sarossy Translational vision science & technology 3 (6), 1-1, 2014 | 40 | 2014 |