Autocyclized and oxidized forms of SCR 7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner SV Vartak, HA Swarup, V Gopalakrishnan, VK Gopinatha, V Ropars, ... The FEBS journal 285 (21), 3959-3976, 2018 | 46 | 2018 |
Modulation of DNA double-strand break repair as a strategy to improve precise genome editing U Ray, SC Raghavan Oncogene 39 (41), 6393-6405, 2020 | 38 | 2020 |
Identification and characterization of novel SCR7‐based small‐molecule inhibitor of DNA end‐joining, SCR130 and its relevance in cancer therapeutics U Ray, SK Raul, VK Gopinatha, D Ghosh, KS Rangappa, K Mantelingu, ... Molecular Carcinogenesis 59 (6), 618-628, 2020 | 24 | 2020 |
NHEJ inhibitor SCR7 and its different forms: Promising CRISPR tools for genome engineering U Ray, SV Vartak, SC Raghavan Gene 763, 144997, 2020 | 19 | 2020 |
Understanding the DNA double-strand break repair and its therapeutic implications U Ray, SC Raghavan DNA repair 106, 103177, 2021 | 18 | 2021 |
SCR7, an inhibitor of NHEJ can sensitize tumor cells to ionization radiation V Gopalakrishnan, S Sharma, U Ray, M Manjunath, D Lakshmanan, ... Molecular Carcinogenesis 60 (9), 627-643, 2021 | 11 | 2021 |
Discovery of novel approach for regioselective synthesis of thioxotriaza-spiro derivatives via oxalic acid VK Gopinatha, HA Swarup, SC Raghavan, K Mantelingu, KS Rangappa Synlett 30 (17), 2004-2009, 2019 | 11 | 2019 |
Inhibitors of DNA double-strand break repair at the crossroads of cancer therapy and genome editing U Ray, SC Raghavan Biochemical Pharmacology 182, 114195, 2020 | 10 | 2020 |
Synthesis and biological evaluation of theophylline methyl 1, 3, 4-oxadiazole as anticancer agents VK Gopinatha, U Ray, K Mantelingu, SC Raghavan, KS Rangappa Russian Journal of Bioorganic Chemistry 46, 837-844, 2020 | 8 | 2020 |
Water‐soluble SCR7 can abrogate DNA end joining and induce cancer cell death U Ray, AE Jose, R Suresh, U Kaloor, HA Swarup, M Nambiar, ... Clin Oncol Res 2020 (7), 1-7, 2020 | 7 | 2020 |
Identification and characterization of mercaptopyrimidine‐based small molecules as inhibitors of nonhomologous DNA end joining U Ray, VK Gopinatha, S Sharma, L Goyary, B Choudhary, K Mantelingu, ... The FEBS Journal 290 (3), 796-820, 2023 | 5 | 2023 |
Acute toxicity analysis of an inhibitor of BCL2, Disarib, in rats S Sharma, KK Varsha, U Ray, H Siddiqua, AE Jose, S Muninarasimaiah, ... Scientific reports 11 (1), 9982, 2021 | 4 | 2021 |
G4 DNA present at human telomeric DNA contributes toward reduced sensitivity to γ-radiation induced oxidative damage, but not bulky adduct formation U Ray, S Sharma, I Kapoor, S Kumari, V Gopalakrishnan, SV Vartak, ... International Journal of Radiation Biology 97 (9), 1166-1180, 2021 | 3 | 2021 |
Novel synthetic aromatic thiourea derivatives and investigations on their cytotoxic potential efficacy U Ray, F John, S Pooppadi, J George, S Sharma, SC Raghavan Journal of Heterocyclic Chemistry 58 (1), 40-47, 2021 | 2 | 2021 |
Nonhomologous DNA end joining in mammalian cells U Ray, SC Raghavan Encyclopedia of Cell Biology: Volume 1-6, Second Edition 1, 552-566, 2022 | 1 | 2022 |
Correction to “Design and Synthesis of Ketenimine Sulfonamide Conjugates through Multicomponent Reactions; A Combined Cytotoxic Analysis and Computational Exploration” DJ Prabhu, U Ray, A Rajeev, R Joy, AT George, J George, SC Raghavan, ... ACS omega 8 (49), 47315-47315, 2023 | | 2023 |
Design and Synthesis of Ketenimine Sulfonamide Conjugates through Multicomponent Reactions; A Combined Cytotoxic Analysis and Computational Exploration DJ Prabhu, U Ray, A Rajeev, R Joy, AT George, J George, SC Raghavan, ... ACS omega 8 (41), 38619-38631, 2023 | | 2023 |
Identification and Biochemical Characterization of Novel Inhibitors of Nonhomologous End Joining: Implications in DNA Double-Strand Break Repair and Cancer Therapy U Ray | | 2021 |
Science Repository U Ray, AE Jose, R Suresh, U Kaloor, HA Swarup, M Nambiar, ... in vivo 3, 21-23, 2020 | | 2020 |
Inhibitor of nonhomologous end joining (NHEJ): Implications in DNA double-strand break repair and cancer progression F John, S Pooppadi, J George, U Ray, S Raghavan ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |