Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy S Ma, Y Zhao, WC Lee, LT Ong, PL Lee, Z Jiang, G Oguz, Z Niu, M Liu, ... Nature communications 13 (1), 4118, 2022 | 81 | 2022 |
IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer LT Ong, WC Lee, S Ma, G Oguz, Z Niu, Y Bao, M Yusuf, PL Lee, JY Goh, ... Proceedings of the National Academy of Sciences 119 (31), e2201376119, 2022 | 49 | 2022 |
Expression of kindlin-3 in melanoma cells impedes cell migration and metastasis C Feng, WK Wee, H Chen, LT Ong, J Qu, HF Tan, SM Tan Cell Adhesion & Migration 11 (5-6), 419-433, 2017 | 20 | 2017 |
Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells J Qu, R Ero, C Feng, LT Ong, HF Tan, HS Lee, MHB Ismail, WT Bu, ... Scientific reports 5 (1), 18491, 2015 | 19 | 2015 |
The systemic lupus erythematosus–associated single nucleotide polymorphism rs1143678 in integrin αM cytoplasmic tail generates a 14-3-3ζ binding site that is proinflammatory LT Ong, HF Tan, C Feng, J Qu, SC Loh, S Bhattacharyya, SM Tan The Journal of Immunology 198 (2), 883-894, 2017 | 10 | 2017 |
The binding interface of kindlin‐2 and ILK involves Asp344/Asp352/Thr356 in kindlin‐2 and Arg243/Arg334 in ILK SY Guan, CP Chng, LT Ong, HF Tan, SK Alex Law, SM Tan FEBS letters 592 (1), 112-121, 2018 | 8 | 2018 |
Binary and ternary complexes of FLNa-Ig21 with cytosolic tails of αMß2 integrin reveal dual role of filamin mediated regulation LL Zhiping, LT Ong, D Chatterjee, SM Tan, S Bhattacharjya Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (12), 130005, 2021 | 3 | 2021 |
Investigating the binding interface of kindlin-2 and Integrin-Linked Kinase (ILK). HF Tan, SY Guan, CP Chng, LT Ong, SK Law, SM Tan MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
Supplementary Information for LT Ong, WC Lee, S Ma, G Oguz, Z Niu, Y Bao, M Yusuf, PL Lee, JY Goh, ... | | |