| Specificity of Intersubunit General Anesthetic-binding Sites in the Transmembrane Domain of the Human α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor*♦ DC Chiara, SS Jayakar, X Zhou, X Zhang, PY Savechenkov, KS Bruzik, ... Journal of Biological Chemistry 288 (27), 19343-19357, 2013 | 148 | 2013 |
| Multiple Propofol-binding Sites in a γ-Aminobutyric Acid Type A Receptor (GABAAR) Identified Using a Photoreactive Propofol Analog*♦ SS Jayakar, X Zhou, DC Chiara, Z Dostalova, PY Savechenkov, KS Bruzik, ... Journal of Biological Chemistry 289 (40), 27456-27468, 2014 | 124 | 2014 |
| Mapping General Anesthetic Binding Site(s) in Human α1β3 γ-Aminobutyric Acid Type A Receptors with [3H]TDBzl-Etomidate, a Photoreactive Etomidate Analogue DC Chiara, Z Dostalova, SS Jayakar, X Zhou, KW Miller, JB Cohen Biochemistry 51 (4), 836-847, 2012 | 114 | 2012 |
| Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog SS Jayakar, WP Dailey, RG Eckenhoff, JB Cohen Journal of Biological Chemistry 288 (9), 6178-6189, 2013 | 81 | 2013 |
| AMPA receptor regulation mechanisms: future target for safer neuroprotective drugs SS Jayakar, M Dikshit International journal of neuroscience 114 (6), 695-734, 2004 | 76 | 2004 |
| 3-Chloro-2-methylphenyl-substituted semicarbazones: synthesis and anticonvulsant activity P Yogeeswari, R Thirumurugan, R Kavya, JS Samuel, J Stables, D Sriram European journal of medicinal chemistry 39 (8), 729-734, 2004 | 72 | 2004 |
| Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites! AK Hamouda, SS Jayakar, DC Chiara, JB Cohen Journal of Molecular Neuroscience 53, 480-486, 2014 | 38 | 2014 |
| Developing nociceptor-selective treatments for acute and chronic pain S Jayakar, J Shim, S Jo, BP Bean, I Singeç, CJ Woolf Science translational medicine 13 (619), eabj9837, 2021 | 36 | 2021 |
| Cannabidiol activates neuronal Kv7 channels HXB Zhang, L Heckman, Z Niday, S Jo, A Fujita, J Shim, R Pandey, ... Elife 11, e73246, 2022 | 33 | 2022 |
| PACAP/PAC1R signaling modulates acetylcholine release at neuronal nicotinic synapses PC Pugh, SS Jayakar, JF Margiotta Molecular and Cellular Neuroscience 43 (2), 244-257, 2010 | 31 | 2010 |
| Positive and negative allosteric modulation of an α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor by binding to a site in the transmembrane domain at the γ+-β− interface SS Jayakar, X Zhou, PY Savechenkov, DC Chiara, R Desai, KS Bruzik, ... Journal of Biological Chemistry 290 (38), 23432-23446, 2015 | 30 | 2015 |
| Identifying drugs that bind selectively to intersubunit general anesthetic sites in the α1β3γ2 GABAAR transmembrane domain SS Jayakar, X Zhou, DC Chiara, C Jarava-Barrera, PY Savechenkov, ... Molecular pharmacology 95 (6), 615-628, 2019 | 27 | 2019 |
| Orthosteric and allosteric ligands of nicotinic acetylcholine receptors for smoking cessation TS Mohamed, SS Jayakar, AK Hamouda Frontiers in molecular neuroscience 8, 71, 2015 | 25 | 2015 |
| Scalable generation of sensory neurons from human pluripotent stem cells T Deng, VM Jovanovic, CA Tristan, C Weber, PH Chu, J Inman, S Ryu, ... Stem Cell Reports 18 (4), 1030-1047, 2023 | 23 | 2023 |
| PACAP induces plasticity at autonomic synapses by nAChR-dependent NOS1 activation and AKAP-mediated PKA targeting SS Jayakar, PC Pugh, Z Dale, ER Starr, S Cole, JF Margiotta Molecular and Cellular Neuroscience 63, 1-12, 2014 | 23 | 2014 |
| Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors SS Jayakar, DC Chiara, X Zhou, B Wu, KS Bruzik, KW Miller, JB Cohen Journal of Biological Chemistry 295 (33), 11495-11512, 2020 | 17 | 2020 |
| Biology and pathophysiology of symptomatic neuromas CD Hwang, YAJ Hoftiezer, FV Raasveld, B Gomez-Eslava, ... Pain 165 (3), 550-564, 2024 | 12 | 2024 |
| Competitive antagonism of anesthetic action at the γ-aminobutyric acid type A receptor by a novel etomidate analog with low intrinsic efficacy C Ma, E Pejo, M McGrath, SS Jayakar, X Zhou, KW Miller, JB Cohen, ... Anesthesiology 127 (5), 824-837, 2017 | 11 | 2017 |
| Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies M McGrath, H Hoyt, A Pence, SS Jayakar, X Zhou, SA Forman, JB Cohen, ... Anesthesiology 133 (3), 583-594, 2020 | 10 | 2020 |
| Etomidate and etomidate analog binding and positive modulation of γ-aminobutyric acid type A receptors: evidence for a state-dependent cutoff effect M McGrath, Z Yu, SS Jayakar, C Ma, M Tolia, X Zhou, KW Miller, ... Anesthesiology 129 (5), 959-969, 2018 | 10 | 2018 |
