| Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts DW Fry, PJ Harvey, PR Keller, WL Elliott, MA Meade, E Trachet, ... Molecular cancer therapeutics 3 (11), 1427-1438, 2004 | 1457 | 2004 |
| Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6 PL Toogood, PJ Harvey, JT Repine, DJ Sheehan, SN VanderWel, H Zhou, ... Journal of medicinal chemistry 48 (7), 2388-2406, 2005 | 617 | 2005 |
| Inhibition of protein− protein association by small molecules: Approaches and progress PL Toogood Journal of medicinal chemistry 45 (8), 1543-1558, 2002 | 406 | 2002 |
| A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6 LB Baughn, M Di Liberto, K Wu, PL Toogood, T Louie, R Gottschalk, ... Cancer research 66 (15), 7661-7667, 2006 | 296 | 2006 |
| Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists X Hu, Y Wang, LY Hao, X Liu, CA Lesch, BM Sanchez, JM Wendling, ... Nature chemical biology 11 (2), 141-147, 2015 | 240 | 2015 |
| Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4 SN VanderWel, PJ Harvey, DJ McNamara, JT Repine, PR Keller, J Quin, ... Journal of medicinal chemistry 48 (7), 2371-2387, 2005 | 238 | 2005 |
| Pyrido[2,3-d]pyrimidin-7-one Inhibitors of Cyclin-Dependent Kinases M Barvian, DH Boschelli, J Cossrow, E Dobrusin, A Fattaey, A Fritsch, ... Journal of medicinal chemistry 43 (24), 4606-4616, 2000 | 226 | 2000 |
| Antifeedant effects of azadirachtin and structurally related compounds on lepidopterous larvae WM Blaney, MSJ Simmonds, SV Ley, JC Anderson, PL Toogood Entomologia experimentalis et applicata 55 (2), 149-160, 1990 | 220 | 1990 |
| Synthesis of (−)-PNU-286607 by asymmetric cyclization of alkylidene barbiturates JC Ruble, AR Hurd, TA Johnson, DA Sherry, MR Barbachyn, PL Toogood, ... Journal of the American Chemical Society 131 (11), 3991-3997, 2009 | 181 | 2009 |
| A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model E Menu, J Garcia, X Huang, M Di Liberto, PL Toogood, I Chen, ... Cancer research 68 (14), 5519-5523, 2008 | 160 | 2008 |
| Ligand recognition by influenza virus. The binding of bivalent sialosides. GD Glick, PL Toogood, DC Wiley, JJ Skehel, JR Knowles Journal of Biological Chemistry 266 (35), 23660-23669, 1991 | 160 | 1991 |
| Cyclin‐dependent kinase inhibitors for treating cancer PL Toogood Medicinal Research Reviews 21 (6), 487-498, 2001 | 131 | 2001 |
| Azadirachtin: structural requirements for reducing growth and increasing mortality in lepidopterous larvae MSJ Simmonds, WM Blaney, SV Ley, JC Anderson, PL Toogood Entomologia experimentalis et applicata 55 (2), 169-181, 1990 | 99 | 1990 |
| Mitochondrial drugs PL Toogood Current opinion in chemical biology 12 (4), 457-463, 2008 | 95 | 2008 |
| Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity X Hu, X Liu, J Moisan, Y Wang, CA Lesch, C Spooner, RW Morgan, ... Oncoimmunology 5 (12), e1254854, 2016 | 94 | 2016 |
| 2-(Pyridin-2-ylamino)-pyrido [2, 3-d] pyrimidin-7-ones M Barvian, RJ Booth, J Quin III, JT Repine, DJ Sheehan, PL Toogood, ... US Patent 6,936,612, 2005 | 92 | 2005 |
| 2-Aminopyridine substituted heterocycles C Biwersi, D McNamara, J Repine, P Toogood, S Vanderwel, J Warmus US Patent App. 10/759,749, 2004 | 88 | 2004 |
| Mechanism of protein synthesis inhibition by didemnin B in vitro BV SirDeshpande, PL Toogood Biochemistry 34 (28), 9177-9184, 1995 | 87 | 1995 |
| Monovalent sialosides that bind tightly to influenza A virus PL Toogood, PK Galliker, GD Glick, JR Knowles Journal of medicinal chemistry 34 (10), 3138-3140, 1991 | 87 | 1991 |
| Insect antifeedants from Azadirachta indica (part 5): Chemical modification and structure-activity relationships of azadirachtin and some related limonoids SV Ley, JC Anderson, WM Blaney, PS Jones, Z Lidert, ED Morgan, ... Tetrahedron 45 (16), 5175-5192, 1989 | 79 | 1989 |
