Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury R Bertini, M Allegretti, C Bizzarri, A Moriconi, M Locati, G Zampella, ... Proceedings of the National Academy of Sciences 101 (32), 11791-11796, 2004 | 389 | 2004 |
Inhibition of natural killer cell cytotoxicity by interleukin‐6: implications for the pathogenesis of macrophage activation syndrome L Cifaldi, G Prencipe, I Caiello, C Bracaglia, F Locatelli, F De Benedetti, ... Arthritis & rheumatology 67 (11), 3037-3046, 2015 | 289 | 2015 |
Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-κB/Snail1 pathway R Strippoli, I Benedicto, ML Perez Lozano, A Cerezo, M López-Cabrera, ... Disease models & mechanisms 1 (4-5), 264-274, 2008 | 160 | 2008 |
Molecular mechanisms underlying peritoneal EMT and fibrosis R Strippoli, R Moreno-Vicente, C Battistelli, C Cicchini, V Noce, ... Stem cells international 2016 (1), 3543678, 2016 | 144 | 2016 |
Nerve growth factor downregulates inflammatory response in human monocytes through TrkA G Prencipe, G Minnone, R Strippoli, L De Pasquale, S Petrini, I Caiello, ... The Journal of Immunology 192 (7), 3345-3354, 2014 | 131 | 2014 |
Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2 F Casilli, A Bianchini, I Gloaguen, L Biordi, E Alesse, C Festuccia, ... Biochemical pharmacology 69 (3), 385-394, 2005 | 129 | 2005 |
Amplification of the response to Toll‐like receptor ligands by prolonged exposure to interleukin‐6 in mice: implication for the pathogenesis of macrophage activation syndrome R Strippoli, F Carvello, R Scianaro, L De Pasquale, M Vivarelli, S Petrini, ... Arthritis & Rheumatism 64 (5), 1680-1688, 2012 | 128 | 2012 |
Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome G Prencipe, I Caiello, A Pascarella, AA Grom, C Bracaglia, L Chatel, ... Journal of Allergy and Clinical Immunology 141 (4), 1439-1449, 2018 | 124 | 2018 |
RAC1/P38 MAPK signaling pathway controls β1 integrin–induced interleukin-8 production in human natural killer cells F Mainiero, A Soriani, R Strippoli, J Jacobelli, A Gismondi, M Piccoli, ... Immunity 12 (1), 7-16, 2000 | 124 | 2000 |
p38 maintains E-cadherin expression by modulating TAK1–NF-κB during epithelial-to-mesenchymal transition R Strippoli, I Benedicto, M Foronda, ML Perez-Lozano, ... Journal of cell science 123 (24), 4321-4331, 2010 | 113 | 2010 |
Caveolin-1 modulates mechanotransduction responses to substrate stiffness through actin-dependent control of YAP R Moreno-Vicente, DM Pavón, I Martín-Padura, M Català-Montoro, ... Cell reports 25 (6), 1622-1635. e6, 2018 | 109 | 2018 |
Caveolin‐1 deficiency induces a MEK‐ERK 1/2‐Snail‐1‐dependent epithelial–mesenchymal transition and fibrosis during peritoneal dialysis R Strippoli, J Loureiro, V Moreno, I Benedicto, ML Perez Lozano, ... EMBO molecular medicine 7 (1), 102-123, 2015 | 102 | 2015 |
HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway E Toschi, I Bacigalupo, R Strippoli, C Chiozzini, A Cereseto, M Falchi, ... Molecular biology of the cell 17 (4), 1985-1994, 2006 | 91 | 2006 |
Reaching the threshold: a multilayer pathogenesis of macrophage activation syndrome R Strippoli, I Caiello, F De Benedetti The Journal of rheumatology 40 (6), 761-767, 2013 | 85 | 2013 |
IL-6 amplifies TLR mediated cytokine and chemokine production: implications for the pathogenesis of rheumatic inflammatory diseases I Caiello, G Minnone, D Holzinger, T Vogl, G Prencipe, A Manzo, ... PloS one 9 (10), e107886, 2014 | 82 | 2014 |
Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration A Gismondi, J Jacobelli, R Strippoli, F Mainiero, A Soriani, L Cifaldi, ... The Journal of Immunology 170 (6), 3065-3073, 2003 | 77 | 2003 |
Mechanisms of peritoneal fibrosis: focus on immune cells–peritoneal stroma interactions M Terri, F Trionfetti, C Montaldo, M Cordani, M Tripodi, M Lopez-Cabrera, ... Frontiers in immunology 12, 607204, 2021 | 72 | 2021 |
Inhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cells R Strippoli, I Benedicto, ML Perez Lozano, T Pellinen, P Sandoval, ... PloS one 7 (2), e31492, 2012 | 66 | 2012 |
Sestrins at the interface of ROS control and autophagy regulation in health and disease M Cordani, M Sánchez-Álvarez, R Strippoli, AV Bazhin, M Donadelli Oxidative Medicine and Cellular Longevity 2019 (1), 1283075, 2019 | 59 | 2019 |
Key role of proline‐rich tyrosine kinase 2 in interleukin‐8 (CXCL8/IL‐8)‐mediated human neutrophil chemotaxis V Di Cioccio, R Strippoli, C Bizzarri, G Troiani, MN Cervellera, I Gloaguen, ... Immunology 111 (4), 407-415, 2004 | 59 | 2004 |